FUNCTION FOUNDATIONS STUDY GUIDE WITH
COMPLETE SOLUTIONS!!
• List, in order of largest to smallest, the major components of the whole muscle.
answers: tendon -> deep fascia -> skeletal muscle -> epimysium -> perimysium ->
fascicle -> endomysium -> Basement membrane -> muscle fiber -> sarcoplasm ->
sarcolemma -> satellite cell -> myofibril -> sarcomere -> myosin -> actin
• Discuss the importance of connective tissue as it relates to skeletal muscle.
answers: the tissues around the different parts of the muscle separate the parts and
hold them into position.
• List and define the anatomical components that make up a muscle fiber.
answers: • Sarcolemma
- Muscle cell membrane
- Protection
- Regulates transport in and out of cell - Conducts action potential
• Sarcoplasm
- Fluid part of muscle fiber
- Contains nuclei, mitochondria, glycogen stores, myoglobin and other organelles
• Myofibrils
- Contain contractile proteins
• Actin (thin filament)
• Myosin (thick filament)
, • Sarcomere
- Z line, M line, H zone, A band, I band
• Sarcoplasmic reticulum
- Storage sites for calcium
- Terminal cisternae
• Transverse tubules
- Extend from sarcolemma to sarcoplasmic reticulum
• Identify the structures that characterize a skeletal muscle fiber's striated
appearance.
answers: these strips are produced by alternating light and dark bans that appear
across the length of the fiber; dark bands contain the primary muscle contractile
proteins and will be discussed in detail later. specifically the A band and the I band
• Describe the role of regulatory proteins (troponin and tropomyoson) in
controlling muscle contraction.
answers: Troponin and tropomyosin are two regulatory proteins that sit on he actin
molecule and control its interaction with myosin. Tropomyosin is attached to actin
directly on the myosin binding site and stays there until troponin acts on the
tropomyosin to move it out of the way. this occurs due to the release of calcium
into the muscle cell which the binds to troponin C.
• Discuss the role of non-contractile proteins (3 examples) for stabilizing and
anchoring the sarcomere structure.
answers: titin - an elastic filament that attaches myofibrils to the Z-line
m protien - a molecule in the M band that anchors myosin