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Adsorption - ✔✔✔occurs when one agent binds the other to its surface to form a complex
Absorption - ✔✔✔process that occurs from the time a drug enters the body to the time it enters the
bloodstream to be circulated
Bioavailability - ✔✔✔Is the portion of a dose that reaches the systemic circulation and is available to act
on body cells
Distribution - ✔✔✔Involves the transport of drug molecules within the body
An important factor in distribution is: - ✔✔✔Protein binding
What two ways allows drugs to enter the blood brain barrier? - ✔✔✔Drugs must be lipid soluble or
Have a transport system that can cross the blood-brain barrier and reach therapeutic concentrations in
brain tissue
What is a common carrier for drugs in the body? - ✔✔✔plasma proteins (mainly albumin)
What part of the drug acts on body cells? - ✔✔✔The free or unbound portion of the drug
What happens to bound drug when plasma drug levels decrease? - ✔✔✔Some of the bound drug is
released
What allows a part of a drug dose to be stored and released as needed? - ✔✔✔Protein binding
Conditions that may decrease plasma albumin levels - ✔✔✔Liver Disease
Inflammatory Disease