INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION
o o o o
by Susan M Ford
o o o
, Chapter 01, General Principles of Pharmacology
1. Afteroteachingoaogroupoofostudentsoaboutotheobasicsoofopharmacology,otheostudentsowillobeoableot
oochooseowhichoaspectoasotheomostocriticalotooremember?
A) Drugoname
B) Drugoclass
C) Drugoaction
D) Drugosource
Answer:oC
Rationale:oPharmacologyoisotheostudyoofodrugsoandoitsoactionoonolivingoorganisms.oThus,oanoess
entialoaspectoofopharmacologyoisodrugoaction.oAnounderstandingoofotheodrugoname,odrugoclass,o
andodrugosourceoisoimportant,obutotheomostocriticaloaspectorelatedotoopharmacologyoisohowotheod
rugoactsoinotheobody.
QuestionoFormat:oMultipleoChoiceo
Chapter:o1
LearningoObjective:o1oCogniti
veoLevel:oApply
ClientoNeeds:oPhysiologicaloIntegrity:oPharmacologicaloTherapiesoIntegr
atedoProcess:oTeaching/Learning
Reference:op.o3,oIntroduction
2. Aonurseosuspectsotheoclientohadoanoadverseoreactionotooaoprescribedomedicationodueotooanoi
nteractionowithoanounreportedoover-the-
counterosupplement.oWhichoactionobyotheonurseowillobestoassistoinopreventingofutureosimil
aroincidents?
A) FileoaoreportowithoMedWatch
B) FileoaoreportowithotheoStateoBoardoofoNursing
C) Instructotheoclientotooavoidocombiningomedicationsoinotheofuture
D) Documentotheoincidentoandoreportoitotootheohealthocareoprovider
Answer:oA
Rationale:oNursesoplayoanoimportantoroleoinomonitoringoforoadverseoreactions.oTherefore,oitoisoi
mportantotoosubmitoreports,oevenoifothereoisouncertaintyoaboutotheocause–
effectorelationship.oTheoFDAoprotectsotheoidentityoofothoseowhoovoluntarilyoreportoadverseoreac
tions.
QuestionoFormat:oMultipleoChoiceo
Chapter:o1
LearningoObjective:o9oCogniti
veoLevel:oApply
, ClientoNeeds:oSafeoandoEffectiveoCareoEnvironment:oSafetyoando InfectionControl
IntegratedoProcess:oClinicaloProblem-
solvingoProcesso(NursingoProcess)oReference:op.o7,oBoxo1.1oMedWatchoa
ndoReportingoAdverseoEvents
3. Aonurseoisoassessingoaoclientoandonotesotheoclientohasodevelopedoswellingoofotheoeyelidsoandoli
psoafteroadministrationoofoaoprescribedomedication.oWhatodoesotheonurseointerpretothisofinding
otoospecificallyoindicate?
A) Mildoallergicoreaction
B) Anaphylacticoshock
C) Angioedema
D) Drugoidiosyncrasy
Answer:oC
Rationale:oAngioedemaoisoaotypeoofoallergicodrugoreactionomanifestedobyotheocollectionoofofluid
oinotheosubcutaneous otissues,omostocommonlyoaffectingotheoeyelids, olips,omouth,oandothroat.oAll
ergicoreactionsocanobeomanifestedobyoaowideorangeoofosignsoandosymptomsosuchoasoitching,orash
es,oandohives.oAnaphylacticoshockoisoaoseriousoallergicoreactionothatorequiresoimmediateomedic
aloattention.oDrugoidiosyncrasydescribesoanyunusualooroabnormaloreactionotooaodrug,ooneothatoiso
differentofromotheooneonormallyoexpected.
QuestionoFormat:oMultipleoChoiceo
Chapter:o1
LearningoObjective:o5oCogniti
veoLevel:oApply
ClientoNeeds:oPhysiologicaloIntegrity:oReductionoofoRiskoPotentialoIntegratedoProc
ess:oClinicaloProblem-
solvingoProcesso(NursingoProcess)oReference:op.o12,oAllergicoDrugoReactions
4. Theonurseoisopreparingotooteachoaoclientoaboutoaonewodrugowhichoisoinotheofourthophaseoofodevel
opment.oWhichoactivityowillotheonurseoexplainobestoillustratesothisophase?
A) HealthocareoprovidersoreportoadverseoeffectsotooFDA.
B) Healthyovolunteersoareoinvolvedoinotheotest.
C) Inovitrootestsoareoperformedousingohumanocells.
D) Theodrugoisogivenotooclientsowithotheodisease.
Answer:oA
, Rationale:oTheopostmarketingosurveillanceophaseoofodrugodevelopmentoencouragesohealthocareo
professionalsotooreportoadverseoeffectsoofodrugsotootheoFDAo usingoMedWatch.oPhaseo1oofoclinicalot
estingoinvolveso20otoo100ohealthyovolunteers.oInovitrootestingoofotheodrugoonohumanooroanimaloce
llsoisodoneoinotheopre-
FDAophase.oInoPhaseo2oofoclinicalotesting,otheodrugoisogivenotooclientsowithotheodiseaseoforowhichoth
eodrugoisomanufactured.
QuestionoFormat:oMultipleoChoiceo
Chapter:o1
LearningoObjective:o4oCogniti
veoLevel:oApply
ClientoNeeds:oHealthoPromotionoandoMaintenanceoIntegra
tedoProcess:oTeaching/LearningoReference:op.o7,oConcepto
MasteryoAlert
5. Aonurseoisoassessingoaopregnantoclientowhooadmitsotoohavingoaococaineoaddiction.oWhichoc
onditionoofotheobabyoafterobirthoshouldotheonurseoexplainoandopreparetheoclientofor?
A) Diabetes
B) Hypertension
C) Addictionotoodrugs
D) CNSodefects
Answer:oC
Rationale:oTheonurseoinformsotheoclientothatochildrenobornotoomothersousingoaddictiveodrugsoa
reooftenobornowithoanoaddictionotootheodrug.oChildrenobornotoomothersowhooareoaddictedotooco
caineoareonotoknownotoobeobornowithodiabetes,oCNSodefects,oorohypertension.
QuestionoFormat:oMultipleoChoiceo
Chapter:o1
LearningoObjective:o6oCogniti
veoLevel:oApply
ClientoNeeds:oHealthoPromotionoandoMaintenanceoIntegrat
edoProcess:oTeaching/Learning
Reference:op.o11,oDrugoUse,oPregnancy,oandoLactation
6. Aoclientoarrivesoatotheohealthocareoclinicoandoreportsotakingoseveralopillsoforoaoheadacheandos
evereocoughowithoutorelief.oWhichoadverseoeffectoshouldotheonurseobeoawareomayodevelopofr
omothisocombination?
A) Gastrointestinalobleeding
B) Breathingodifficulties
C) Liverodamage
D) Anaphylaxis