HESI Exit Exam Pharmacology Practice Questions
80 NCLEX-Style Multiple-Choice Questions for Exam Preparation
Covering Drug Classifications, Side Effects, Nursing Interventions, Dosage Calculations, and
Patient Teaching
Practice Questions
Question 1: A nurse is administering enalapril to a client with heart failure. To which drug
class does enalapril belong?
A) Beta-blocker
B) ACE inhibitor
C) Diuretic
D) Calcium channel blocker
Correct Answer: B) ACE inhibitor
Question 2: A client taking glipizide reports shakiness and sweating. What is the nurses pri-
ority action?
A) Administer the next dose as scheduled.
B) Check the clients blood glucose level.
C) Provide a high-protein snack.
D) Encourage the client to rest.
Correct Answer: B) Check the clients blood glucose level.
Question 3: A client is prescribed apixaban. Which laboratory value should the nurse moni-
tor?
A) PT/INR
B) aPTT
C) Platelet count
D) Serum creatinine
Correct Answer: D) Serum creatinine
Question 4: A nurse is to administer 600 mg of ibuprofen PO. The pharmacy provides 200 mg
tablets. How many tablets should the nurse administer?
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Correct Answer: C) 3 tablets
Question 5: A client receiving oxycodone reports drowsiness. What should the nurse do?
A) Encourage the client to increase activity.
B) Monitor the clients level of consciousness.
C) Administer the next dose as scheduled.
D) Provide a stimulant to counter drowsiness.
Correct Answer: B) Monitor the clients level of consciousness.
1
, Question 6: A client is prescribed bumetanide. What is the primary indication for this medi-
cation?
A) Hypertension
B) Edema
C) Hyperglycemia
D) Pain management
Correct Answer: B) Edema
Question 7: A nurse is teaching a client about salmeterol. Which side effect should the nurse
include?
A) Sedation
B) Tachycardia
C) Hypotension
D) Constipation
Correct Answer: B) Tachycardia
Question 8: A client receiving enoxaparin develops swelling at the injection site. What should
the nurse do?
A) Massage the site to promote absorption.
B) Apply ice and monitor the site.
C) Administer the next dose at the same site.
D) Apply heat to reduce swelling.
Correct Answer: B) Apply ice and monitor the site.
Question 9: A nurse is to administer 1 g of vancomycin IV in 250 mL of fluid over 90 minutes.
What is the infusion rate in mL/hr?
A) 100 mL/hr
B) 167 mL/hr
C) 200 mL/hr
D) 250 mL/hr
Correct Answer: B) 167 mL/hr
Question 10: A client taking levothyroxine reports palpitations. What should the nurse do first?
A) Encourage the client to increase fluid intake.
B) Assess the clients thyroid hormone levels.
C) Administer the next dose as scheduled.
D) Provide a sedative to calm the client.
Correct Answer: B) Assess the clients thyroid hormone levels.
Question 11: To which drug class does rosuvastatin belong?
A) Anticoagulant
B) Statin
C) Antihypertensive
D) Antidepressant
Correct Answer: B) Statin
Question 12: A client receiving chemotherapy is prescribed granisetron. What is the purpose
of this medication?
A) Pain relief
B) Nausea prevention
C) Infection prevention
2
80 NCLEX-Style Multiple-Choice Questions for Exam Preparation
Covering Drug Classifications, Side Effects, Nursing Interventions, Dosage Calculations, and
Patient Teaching
Practice Questions
Question 1: A nurse is administering enalapril to a client with heart failure. To which drug
class does enalapril belong?
A) Beta-blocker
B) ACE inhibitor
C) Diuretic
D) Calcium channel blocker
Correct Answer: B) ACE inhibitor
Question 2: A client taking glipizide reports shakiness and sweating. What is the nurses pri-
ority action?
A) Administer the next dose as scheduled.
B) Check the clients blood glucose level.
C) Provide a high-protein snack.
D) Encourage the client to rest.
Correct Answer: B) Check the clients blood glucose level.
Question 3: A client is prescribed apixaban. Which laboratory value should the nurse moni-
tor?
A) PT/INR
B) aPTT
C) Platelet count
D) Serum creatinine
Correct Answer: D) Serum creatinine
Question 4: A nurse is to administer 600 mg of ibuprofen PO. The pharmacy provides 200 mg
tablets. How many tablets should the nurse administer?
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Correct Answer: C) 3 tablets
Question 5: A client receiving oxycodone reports drowsiness. What should the nurse do?
A) Encourage the client to increase activity.
B) Monitor the clients level of consciousness.
C) Administer the next dose as scheduled.
D) Provide a stimulant to counter drowsiness.
Correct Answer: B) Monitor the clients level of consciousness.
1
, Question 6: A client is prescribed bumetanide. What is the primary indication for this medi-
cation?
A) Hypertension
B) Edema
C) Hyperglycemia
D) Pain management
Correct Answer: B) Edema
Question 7: A nurse is teaching a client about salmeterol. Which side effect should the nurse
include?
A) Sedation
B) Tachycardia
C) Hypotension
D) Constipation
Correct Answer: B) Tachycardia
Question 8: A client receiving enoxaparin develops swelling at the injection site. What should
the nurse do?
A) Massage the site to promote absorption.
B) Apply ice and monitor the site.
C) Administer the next dose at the same site.
D) Apply heat to reduce swelling.
Correct Answer: B) Apply ice and monitor the site.
Question 9: A nurse is to administer 1 g of vancomycin IV in 250 mL of fluid over 90 minutes.
What is the infusion rate in mL/hr?
A) 100 mL/hr
B) 167 mL/hr
C) 200 mL/hr
D) 250 mL/hr
Correct Answer: B) 167 mL/hr
Question 10: A client taking levothyroxine reports palpitations. What should the nurse do first?
A) Encourage the client to increase fluid intake.
B) Assess the clients thyroid hormone levels.
C) Administer the next dose as scheduled.
D) Provide a sedative to calm the client.
Correct Answer: B) Assess the clients thyroid hormone levels.
Question 11: To which drug class does rosuvastatin belong?
A) Anticoagulant
B) Statin
C) Antihypertensive
D) Antidepressant
Correct Answer: B) Statin
Question 12: A client receiving chemotherapy is prescribed granisetron. What is the purpose
of this medication?
A) Pain relief
B) Nausea prevention
C) Infection prevention
2
