ABFT Exam 216 Questions with Verified Answers
Founder of USA toxicology - CORRECT ANSWER Alexander Gettler
"The dose makes the poison" - CORRECT ANSWER Paracelsus
First attempt to categorize poisons - CORRECT ANSWER M.J.B. Orfila
First method for extracting alkaloids - CORRECT ANSWER Jean Stas
Improvement to alkaloid extraction - CORRECT ANSWER F.J. Otto
Extensive study on phamacology of alcohol - CORRECT ANSWER Erik Widmark
Invented Drunkometer - CORRECT ANSWER Rolla Harger
Invented Breathalyzer - CORRECT ANSWER Robert Borkenstein
Federal Register 1986 - CORRECT ANSWER Federal employees in safety- and
security-sensitive positions must be drug tested
,Federal Register 1988a - CORRECT ANSWER publication of Mandatory Guidelines
for Drug Testing of Federal Employees by Dept. of HHS; rules for airline, pipeline,
RR, and trucking
Federal Register 1988b - CORRECT ANSWER CFR Part 40: Procedures for
transportation employee drug and alcohol testing
In a suspected chronic poisoning, the best single specimen for elucidation of
heavy metals - CORRECT ANSWER Hair
Sodium fluoride effective as preservative in whole blood at - CORRECT ANSWER
1.0%
Single most important specimen to collect - CORRECT ANSWER Blood
From which sites should blood be collected and why - CORRECT ANSWER
Heart/central, and femoral or ileac/peripheral; in order to minimize
contamination or elucidate redistribution
Stable and isolated specimen in PM cases - CORRECT ANSWER Vitreous humor
Why collect urine specimen - CORRECT ANSWER Drugs stable longer, higher
concentration. Some testing can be performed with minimal sample prep
,Can concentrate certain drugs, e.g. benzodiazepines - CORRECT ANSWER Bile
Red top tube - CORRECT ANSWER No additives
Gray - CORRECT ANSWER potassium oxalate and sodium fluoride
Green - CORRECT ANSWER Lithium heparin
Blue - CORRECT ANSWER Sodium citrate
Royal blue - CORRECT ANSWER no anticoagulant; for trace metals
Purple - CORRECT ANSWER K2 EDTA
Gastric fluid may be useful for - CORRECT ANSWER Determining route of admin,
non-biological ID (pills, etc.)
How to separate plasma - CORRECT ANSWER Liquid portion of blood; contains 6-
8% protein; centrifuged
How to separate serum - CORRECT ANSWER Liquid portion of blood with no cells
or clotting factors; allowed to clot, then centrifuged
, In suspected heavy metal poisoning, specimen to collect: - CORRECT ANSWER Hair
Adulterated sample - CORRECT ANSWER Urine contains substance that is not
normal constituent or at abnormal concentration.
Dilute sample - CORRECT ANSWER Urine has creatinine and SG values lower than
expected
Federal screening cutoff for cannabinoids - CORRECT ANSWER 50 ng/ml in urine
Federal screening cutoff for cocaine metabolite - CORRECT ANSWER 150 ng/ml in
urine
Federal screening cutoff for opiate metabolites - CORRECT ANSWER 2000 ng/ml in
urine
Federal screening cutoff for 6-AM - CORRECT ANSWER 10 ng/ml in urine
Federal screening cutoff for PCP - CORRECT ANSWER 25 ng/ml in urine
Federal screening cutoff for amphetamines - CORRECT ANSWER 500 ng/ml in
urine
Founder of USA toxicology - CORRECT ANSWER Alexander Gettler
"The dose makes the poison" - CORRECT ANSWER Paracelsus
First attempt to categorize poisons - CORRECT ANSWER M.J.B. Orfila
First method for extracting alkaloids - CORRECT ANSWER Jean Stas
Improvement to alkaloid extraction - CORRECT ANSWER F.J. Otto
Extensive study on phamacology of alcohol - CORRECT ANSWER Erik Widmark
Invented Drunkometer - CORRECT ANSWER Rolla Harger
Invented Breathalyzer - CORRECT ANSWER Robert Borkenstein
Federal Register 1986 - CORRECT ANSWER Federal employees in safety- and
security-sensitive positions must be drug tested
,Federal Register 1988a - CORRECT ANSWER publication of Mandatory Guidelines
for Drug Testing of Federal Employees by Dept. of HHS; rules for airline, pipeline,
RR, and trucking
Federal Register 1988b - CORRECT ANSWER CFR Part 40: Procedures for
transportation employee drug and alcohol testing
In a suspected chronic poisoning, the best single specimen for elucidation of
heavy metals - CORRECT ANSWER Hair
Sodium fluoride effective as preservative in whole blood at - CORRECT ANSWER
1.0%
Single most important specimen to collect - CORRECT ANSWER Blood
From which sites should blood be collected and why - CORRECT ANSWER
Heart/central, and femoral or ileac/peripheral; in order to minimize
contamination or elucidate redistribution
Stable and isolated specimen in PM cases - CORRECT ANSWER Vitreous humor
Why collect urine specimen - CORRECT ANSWER Drugs stable longer, higher
concentration. Some testing can be performed with minimal sample prep
,Can concentrate certain drugs, e.g. benzodiazepines - CORRECT ANSWER Bile
Red top tube - CORRECT ANSWER No additives
Gray - CORRECT ANSWER potassium oxalate and sodium fluoride
Green - CORRECT ANSWER Lithium heparin
Blue - CORRECT ANSWER Sodium citrate
Royal blue - CORRECT ANSWER no anticoagulant; for trace metals
Purple - CORRECT ANSWER K2 EDTA
Gastric fluid may be useful for - CORRECT ANSWER Determining route of admin,
non-biological ID (pills, etc.)
How to separate plasma - CORRECT ANSWER Liquid portion of blood; contains 6-
8% protein; centrifuged
How to separate serum - CORRECT ANSWER Liquid portion of blood with no cells
or clotting factors; allowed to clot, then centrifuged
, In suspected heavy metal poisoning, specimen to collect: - CORRECT ANSWER Hair
Adulterated sample - CORRECT ANSWER Urine contains substance that is not
normal constituent or at abnormal concentration.
Dilute sample - CORRECT ANSWER Urine has creatinine and SG values lower than
expected
Federal screening cutoff for cannabinoids - CORRECT ANSWER 50 ng/ml in urine
Federal screening cutoff for cocaine metabolite - CORRECT ANSWER 150 ng/ml in
urine
Federal screening cutoff for opiate metabolites - CORRECT ANSWER 2000 ng/ml in
urine
Federal screening cutoff for 6-AM - CORRECT ANSWER 10 ng/ml in urine
Federal screening cutoff for PCP - CORRECT ANSWER 25 ng/ml in urine
Federal screening cutoff for amphetamines - CORRECT ANSWER 500 ng/ml in
urine
