Neuropharmacology - Advanced Pharm -
NURS8024 - Exam Three
__________ ____________ ___________ _ _ _ _ _ _ _ _ _ may be an alternate treatment
for seizure patients unsuccessful with other drug txs. - ANS-Vagal Nerve Stimulation
\1st Line for moderate to severe Migraine HA? - ANS-Triptans like Sumatriptan
\A ADE to include in patient education for SNRIs would include: - ANS-Sexual dysfunction /
Constipation / and BBW of Increase in Suicidal Ideations
\A common Atypical Antidepressant that is prescribed for sleep and has an ADE of priapism
is? - ANS-Trazodone
\A HA lasting more than 2 hours and made worse by physical activity is a ______________ .
- ANS-Migraine
\ADE for Antipsychotics include: - ANS-EPS
\ADE for Phenytoin include ___________ especially with _________. - ANS-GINGIVAL
HYPERPLASIA, impaired cognition, body hair growth, Vitamin D and FOLIC ACID Def ;
PREGNANCY
\ADE of dopamine receptor agonists include: - ANS-GI, Postural HYPO, Dyskinesias,
confusion, delusions, hallucinations, IMPULSIVITY
\ADE of NamENDa includes _________________ and CAUTION in __________________.
- ANS-Constipation, confusion, dizziness, HA, Hallucination, Cough, HTN ; Renal
Impairment.
\ADE with Benzo - BIG ONE? - ANS-Sedation, Addictive effect and CYP450 / Pregnancy D
\ADE with GABA Analogs include: - ANS-EDEMA
Somnolence
Dizziness
Ataxia
\ADE with Levodopa include: - ANS-CNS effects (Visual/Auditory Hallucinations, AIM,
depression, GI effects, Tachy, Acute glaucoma
\ADEs and Serious ADES of Migraine Medication include: - ANS-Chest pressure, fatigue,
dizziness, flushing ; V-Fib and other Cardiac Issues
\ADEs for Wellbutrin (Bupropion) include _________ with extra awareness to
__________________ . - ANS-Dry mouth, sweating, nervousness, tremor
Decrease in Seizure Threshold
\After PCP consult which medication can be started for EARLY Alzheimers Disease? -
ANS-Donepezil (Aricept or EARLYCEPT), Rivastigmine (Exelon), Galantamine (Razadyne)
\Amantadine is used to treat? - ANS-MINOR Parkinsons
\An experienced NP would know what about medication to treat Alzheimers disease? -
ANS-Drugs are palliative - Provides only modest ST benefits - FATAL
, \An NP is working with a patient that is habitually non-compliance with their antidepressant
medication. What drug would be a good option to the long 1/2 life? - ANS-Prozac
(Fluoxetine)
\An NP knows you cannot _________________ stop Alzheimers Disease medication. -
ANS-Abruptly
\An NP understand that treatment effectiveness _____________ between the 3rd and 5th
year of Parkinson treatment using sinemet. - ANS-Decreases
\An NP would be cautious in prescribing Amantadine for minor Parkinson's in a patient with
what dx? - ANS-Seizure D/O & CHF
\Anticholinergics in Parkinson's disease are prescribed because........ - ANS-Decrease
Tremors
Decrease Rigidity
Decrease Drooling
\BBW of ERGOTs: - ANS-Serious peripheral ischemia
\CAUTION when RX MAOIs with _________ or ________ because _____________ can
occur. - ANS-Bupropion (Wellbutrin) or SSRIs ; Serotonin Syndrome
\CAUTION when using _______________ & ___________ as both are major enzymes that
metabolize catecholamines. - ANS-MAO-B and COMT
\Caution with a hx of __________ when prescribing TCAs. - ANS-CVD
\CAUTION with Migraine Medication - ANS-MAOIs may cause Serotonin Syndrome - Avoid
to 2 weeks
\Cogentin / Benzotropine is an________________ drug - ANS-Anticholinergic
\Common example of an SSRI that has the longest 1/2 life? - ANS-Prozac (Fluoxetine)
\COMT (Catehcol-O-Methyltransferase Inhibitors) - ANS-Help with uptake of Levodopa
which increases dopamine in CNS
\Consideration when prescribing antiepileptic drugs include CAUTION in: - ANS-Renal and
Hepatic DX
\Describe the MOA of Venlafaxine (Effexor) and Duloxetine (Cymbalta): - ANS-Inhibits
reuptake of serotonin and norepinephrine when SSRIs DO NOT WORK
\Do not ____________ ergots in pregnancy and lactation. - ANS-Use / Rx
\Do not use Ergots within 24 hours of _________________ . - ANS-Triptans
\Dylan is a 23 y/o man just started on Prozac. As an NP which patient education would be
important to educate Dylan on? - ANS-Sexual dysfunction and monitor for increased Suicidal
Ideations
\Ergot give with caffeine is named _______________ . - ANS-Cafergot
\Ergots overuse may cause ____________ including ______________. - ANS-Intense
arterial constriction ; gangrene
\How does Carbidopa help in Parkinson's disease? - ANS-Carbidopa enhances availability of
levodopa to cross the BBB. Decrease metabolism of levodopa in the GI system
\Hydroxyzine is ___________ and _____________ prescribed for _______________. -
ANS-Antihistamine ; Antiemetic ; Anxiety
\Hypnotics influence the CYP450 System. T / F - ANS-True - MANY DRUG / DRUG
Interactions
\If a patient overdosed on Diazepam which antidote would the NP expect to see prescribed?
- ANS-Flumazenil
\Important Pt Ed on Levodopa: - ANS-Take on an Empty Stomach
NURS8024 - Exam Three
__________ ____________ ___________ _ _ _ _ _ _ _ _ _ may be an alternate treatment
for seizure patients unsuccessful with other drug txs. - ANS-Vagal Nerve Stimulation
\1st Line for moderate to severe Migraine HA? - ANS-Triptans like Sumatriptan
\A ADE to include in patient education for SNRIs would include: - ANS-Sexual dysfunction /
Constipation / and BBW of Increase in Suicidal Ideations
\A common Atypical Antidepressant that is prescribed for sleep and has an ADE of priapism
is? - ANS-Trazodone
\A HA lasting more than 2 hours and made worse by physical activity is a ______________ .
- ANS-Migraine
\ADE for Antipsychotics include: - ANS-EPS
\ADE for Phenytoin include ___________ especially with _________. - ANS-GINGIVAL
HYPERPLASIA, impaired cognition, body hair growth, Vitamin D and FOLIC ACID Def ;
PREGNANCY
\ADE of dopamine receptor agonists include: - ANS-GI, Postural HYPO, Dyskinesias,
confusion, delusions, hallucinations, IMPULSIVITY
\ADE of NamENDa includes _________________ and CAUTION in __________________.
- ANS-Constipation, confusion, dizziness, HA, Hallucination, Cough, HTN ; Renal
Impairment.
\ADE with Benzo - BIG ONE? - ANS-Sedation, Addictive effect and CYP450 / Pregnancy D
\ADE with GABA Analogs include: - ANS-EDEMA
Somnolence
Dizziness
Ataxia
\ADE with Levodopa include: - ANS-CNS effects (Visual/Auditory Hallucinations, AIM,
depression, GI effects, Tachy, Acute glaucoma
\ADEs and Serious ADES of Migraine Medication include: - ANS-Chest pressure, fatigue,
dizziness, flushing ; V-Fib and other Cardiac Issues
\ADEs for Wellbutrin (Bupropion) include _________ with extra awareness to
__________________ . - ANS-Dry mouth, sweating, nervousness, tremor
Decrease in Seizure Threshold
\After PCP consult which medication can be started for EARLY Alzheimers Disease? -
ANS-Donepezil (Aricept or EARLYCEPT), Rivastigmine (Exelon), Galantamine (Razadyne)
\Amantadine is used to treat? - ANS-MINOR Parkinsons
\An experienced NP would know what about medication to treat Alzheimers disease? -
ANS-Drugs are palliative - Provides only modest ST benefits - FATAL
, \An NP is working with a patient that is habitually non-compliance with their antidepressant
medication. What drug would be a good option to the long 1/2 life? - ANS-Prozac
(Fluoxetine)
\An NP knows you cannot _________________ stop Alzheimers Disease medication. -
ANS-Abruptly
\An NP understand that treatment effectiveness _____________ between the 3rd and 5th
year of Parkinson treatment using sinemet. - ANS-Decreases
\An NP would be cautious in prescribing Amantadine for minor Parkinson's in a patient with
what dx? - ANS-Seizure D/O & CHF
\Anticholinergics in Parkinson's disease are prescribed because........ - ANS-Decrease
Tremors
Decrease Rigidity
Decrease Drooling
\BBW of ERGOTs: - ANS-Serious peripheral ischemia
\CAUTION when RX MAOIs with _________ or ________ because _____________ can
occur. - ANS-Bupropion (Wellbutrin) or SSRIs ; Serotonin Syndrome
\CAUTION when using _______________ & ___________ as both are major enzymes that
metabolize catecholamines. - ANS-MAO-B and COMT
\Caution with a hx of __________ when prescribing TCAs. - ANS-CVD
\CAUTION with Migraine Medication - ANS-MAOIs may cause Serotonin Syndrome - Avoid
to 2 weeks
\Cogentin / Benzotropine is an________________ drug - ANS-Anticholinergic
\Common example of an SSRI that has the longest 1/2 life? - ANS-Prozac (Fluoxetine)
\COMT (Catehcol-O-Methyltransferase Inhibitors) - ANS-Help with uptake of Levodopa
which increases dopamine in CNS
\Consideration when prescribing antiepileptic drugs include CAUTION in: - ANS-Renal and
Hepatic DX
\Describe the MOA of Venlafaxine (Effexor) and Duloxetine (Cymbalta): - ANS-Inhibits
reuptake of serotonin and norepinephrine when SSRIs DO NOT WORK
\Do not ____________ ergots in pregnancy and lactation. - ANS-Use / Rx
\Do not use Ergots within 24 hours of _________________ . - ANS-Triptans
\Dylan is a 23 y/o man just started on Prozac. As an NP which patient education would be
important to educate Dylan on? - ANS-Sexual dysfunction and monitor for increased Suicidal
Ideations
\Ergot give with caffeine is named _______________ . - ANS-Cafergot
\Ergots overuse may cause ____________ including ______________. - ANS-Intense
arterial constriction ; gangrene
\How does Carbidopa help in Parkinson's disease? - ANS-Carbidopa enhances availability of
levodopa to cross the BBB. Decrease metabolism of levodopa in the GI system
\Hydroxyzine is ___________ and _____________ prescribed for _______________. -
ANS-Antihistamine ; Antiemetic ; Anxiety
\Hypnotics influence the CYP450 System. T / F - ANS-True - MANY DRUG / DRUG
Interactions
\If a patient overdosed on Diazepam which antidote would the NP expect to see prescribed?
- ANS-Flumazenil
\Important Pt Ed on Levodopa: - ANS-Take on an Empty Stomach
