@qo @qo
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
WWW.THENURSINGMASTERY.COM
Page @qo1 @qoof
@qo247
,5. The administration @qoof @qooxytocin @qohas @qobeen @qoproposed @qoas @qoa @qotreatment @qofor
@qoautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: @qoc
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
6. Which @qofactor @qodoes @qonot @qoaffect @qothe @qopharmacokinetics @qoof @qoa @qodrug?
a. Route @qoof @qoadministration
b. Lipid @qosolubility
c. Depot @qobinding
d. Drug @qoaction
Answer: @qod
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
7. First-pass @qometabolism @qooccurs @qowhen @qodrugs @qoare @qotaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: @qoa
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
8. The @qoarea @qopostrema @qois @qoone @qoarea @qoin @qothe @qobrain @qowhere @qothe is @qonot @qocomplete.
a. cerebrospinal @qofluid
b. blood–brain @qobarrier
c. choroid @qoplexus
d. phospholipid @qomembrane
Answer: @qob
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
9. First-pass @qometabolism @qooccurs @qowith @qoorally @qoadministered @qodrugs @qobecause
a. their @qoabsorption @qois @qoslowed @qoby @qofood.
b. drugs @qoabsorbed @qointo @qothe @qobloodstream @qofrom @qothe @qostomach @qogo @qoto @qothe
@qoliver @qoon @qothe @qoway @qoto @qogeneral @qocirculation.
c. drugs @qomust @qofirst @qosurvive @qothe @qoacidic @qoenvironment @qoof @qothe @qostomach.
d. salivary @qoenzymes @qoin @qothe @qomouth @qobegin @qothe @qoprocess @qoof @qometabolism.
Answer: @qob
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
10. Toxic @qosubstances @qoin @qothe @qoblood @qotrigger @qoa @qovomiting @qoresponse @qoby @qoactivating
@qothe
a. blood–brain @qobarrier.
b. choroid @qoplexus.
c. area @qopostrema.
d. median @qoeminence.
WWW.THENURSINGMASTERY.COM
Page @qo2 @qoof
@qo247
, Answer: @qoc
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
11. Drugs @qoadministered @qo_ have @qothe @qomost @qorapid @qoonset @qoof @qoaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: @qod
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
12. Ionization @qoof @qoa @qodrug @qodepends @qoon @qothe of @qothe @qosolution @qoand @qothe of
@qothe @qodrug.
a. pH; @qopKa
b. pKa; @qopH
c. concentration; @qolipid @qosolubility
d. pH; @qoconcentration
Answer: @qoa
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
13. The @qoabsorption @qoof @qoa @qodrug @qodepends @qoon @qoall @qoof @qothe @qofollowing @qoexcept
a. lipid @qosolubility.
b. ionization.
c. body @qotemperature.
d. the @qoconcentration @qoof @qothe @qodrug.
Answer: @qoc
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
14. Drugs @qothat @qoare should @qobe @qoavoided @qoby @qowomen @qoof @qochildbearing @qoage.
a. teratogenic
b. able @qoto @qocross @qothe @qoplacental @qobarrier
c. psychoactive
d. highly @qolipid-soluble
Answer: @qoa
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
15. Agents @qothat @qoinduce @qodevelopmental @qoabnormalities @qoin @qoa @qofetus @qoare @qoknown @qoas
a. psychoactive @qodrugs.
b. illicit @qodrugs.
c. teratogens.
d. placental @qodrugs.
Answer: @qoc
Textbook @qoReference: @qoPharmacokinetic @qoFactors @qoDetermining @qoDrug @qoAction
16. Depot @qobinding @qois @qosaid @qoto @qooccur @qowhen @qodrugs
a. bind @qoto @qotheir @qotarget @qosites.
WWW.THENURSINGMASTERY.COM
Page @qo3 @qoof
@qo247