@aq @aq
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration @aqof @aqoxytocin @aqhas @aqbeen @aqproposed @aqas @aqa @aqtreatment @aqfor
@aqautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: @aqc
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
6. Which @aqfactor @aqdoes @aqnot @aqaffect @aqthe @aqpharmacokinetics @aqof @aqa @aqdrug?
a. Route @aqof @aqadministration
b. Lipid @aqsolubility
c. Depot @aqbinding
d. Drug @aqaction
Answer: @aqd
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
7. First-pass @aqmetabolism @aqoccurs @aqwhen @aqdrugs @aqare @aqtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: @aqa
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
8. The @aqarea @aqpostrema @aqis @aqone @aqarea @aqin @aqthe @aqbrain @aqwhere @aqthe is @aqnot @aqcomplete.
a. cerebrospinal @aqfluid
b. blood–brain @aqbarrier
c. choroid @aqplexus
d. phospholipid @aqmembrane
Answer: @aqb
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
9. First-pass @aqmetabolism @aqoccurs @aqwith @aqorally @aqadministered @aqdrugs @aqbecause
a. their @aqabsorption @aqis @aqslowed @aqby @aqfood.
b. drugs @aqabsorbed @aqinto @aqthe @aqbloodstream @aqfrom @aqthe @aqstomach @aqgo @aqto @aqthe
@aqliver @aqon @aqthe @aqway @aqto @aqgeneral @aqcirculation.
c. drugs @aqmust @aqfirst @aqsurvive @aqthe @aqacidic @aqenvironment @aqof @aqthe @aqstomach.
d. salivary @aqenzymes @aqin @aqthe @aqmouth @aqbegin @aqthe @aqprocess @aqof @aqmetabolism.
Answer: @aqb
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
10. Toxic @aqsubstances @aqin @aqthe @aqblood @aqtrigger @aqa @aqvomiting @aqresponse @aqby @aqactivating
@aqthe
a. blood–brain @aqbarrier.
b. choroid @aqplexus.
c. area @aqpostrema.
d. median @aqeminence.
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, Answer: @aqc
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
11. Drugs @aqadministered @aq_ have @aqthe @aqmost @aqrapid @aqonset @aqof @aqaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: @aqd
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
12. Ionization @aqof @aqa @aqdrug @aqdepends @aqon @aqthe of @aqthe @aqsolution @aqand @aqthe of
@aqthe @aqdrug.
a. pH; @aqpKa
b. pKa; @aqpH
c. concentration; @aqlipid @aqsolubility
d. pH; @aqconcentration
Answer: @aqa
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
13. The @aqabsorption @aqof @aqa @aqdrug @aqdepends @aqon @aqall @aqof @aqthe @aqfollowing @aqexcept
a. lipid @aqsolubility.
b. ionization.
c. body @aqtemperature.
d. the @aqconcentration @aqof @aqthe @aqdrug.
Answer: @aqc
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
14. Drugs @aqthat @aqare should @aqbe @aqavoided @aqby @aqwomen @aqof @aqchildbearing @aqage.
a. teratogenic
b. able @aqto @aqcross @aqthe @aqplacental @aqbarrier
c. psychoactive
d. highly @aqlipid-soluble
Answer: @aqa
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
15. Agents @aqthat @aqinduce @aqdevelopmental @aqabnormalities @aqin @aqa @aqfetus @aqare @aqknown @aqas
a. psychoactive @aqdrugs.
b. illicit @aqdrugs.
c. teratogens.
d. placental @aqdrugs.
Answer: @aqc
Textbook @aqReference: @aqPharmacokinetic @aqFactors @aqDetermining @aqDrug @aqAction
16. Depot @aqbinding @aqis @aqsaid @aqto @aqoccur @aqwhen @aqdrugs
a. bind @aqto @aqtheir @aqtarget @aqsites.
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