Aromatic Substitution

1
Chapter 18 – Electrophilic Aromatic Substitution



Chapter 18 – Aromatic Substitution Reactions
Unexpected Bromination of Benzene




Electrophilic Aromatic Substitution




Me when I saw a mirror at the gym

, 2
Chapter 18 – Electrophilic Aromatic Substitution


Rxn1: Halogenation




Mechanism of the formation of Fe-Br complex




Mechanism of Bromination of Benzene




Me when I saw a mirror at the gym

, 3
Chapter 18 – Electrophilic Aromatic Substitution




This is the target




sincedenzene
Rxn2: Sulfonation are




Me when I saw a mirror at the gym

, 4
Chapter 18 – Electrophilic Aromatic Substitution


Rxn3: Nitration




= -1 4 pica
=
-3)stronger
pla
.




- 1
W
↑
: -1 7
pica
.




- 1
H
A ↳
4




under
acidic
Rxn3.1: Reduction of NO2 group condition

↓




Ammulinium On




Me when I saw a mirror at the gym