pharmacologic - grouped according to their psychologic activities and mechanisms of action
therapeutic - classified according to their therapeutic uses
chemical - grouped according to chemical structure
chemical name - describes drug's chemical components and molecular structure
generic name - given by US adopted name council and used in official catalogs of listed drugs
NOT - generic names are _ capitalized
are - trade names _ capitalized
trade name - proprietary name- commercial use restricted to owner/patent manufacturer of
drug
example of class/catergory - drugs affecting the cardiovascular system
example of therapeutic class - anti-hypertensive drug
pharmacologic class example - ace inhibitor
prototype - individual drug that represents the qualities/features of a group of drugs
1906 federal food and drug act - protect public from adulterated or mislabeled drugs
-identify dangerous or addictive drugs
-established official standards
1912 sherley amendment - prohibited fraudulant claims for drug products
1914 harrison narcotic act - established legal term narcotic!
regulated production and sale of habit forming drugd
1938 food drug cosmetic act revison - provide data (testing) proving drug safety before
marketing of new drugs
1951 Durham humphrey amendment to FFDCA - legent/prescription drugs- prohibited without
prescription
narcotics - need new scripts from MD for refill
1962 kefauver harris amendment to FFDCA - manufacturer has to provide research based
evidence to prove SAFETY and THERAPEUTIC efficiency of new drugs
, -prompted by thalidomide tragedy in Europe
1970 comprehensive drug abuse prevention and control act/ controlled substance act -
schedule of drugs I-V
I= nobody should use
FDA requests - BLACK BOX WARNING
-patterns of severe reactions to new drugs/voluntary recalls
FDA drug recalls - class 1- causing death and serious effects
Class 3- least severe
expedited drug approval - make life saving investigational threapies available sooner
Purpose of Nurse Practice Act - protect public from unskilled, undereducated and unlicensed
personell
cellular physiologyq - drugs are chemicals that must reach and interact with or cross the cell
membranes to
-alter basic physiochemical processes
-stimulate or inhibit normal cellular functions
pharmaceutic phase - includes how various dosage forms influences the way the body
metabolizes a drug and the way in which the drug affects the body
-disintegration- the process of coming to pieces
-dissolution- cessation
pharmacokinetic phase - study of what the body does to the drug molecules- includes processes
of the movement of the druge through the body by
-absorption
-distribution
-biotransformation
-excretion
pharmacodynamics - process by which cell physiology is altered by a drug- mechanism of action
-drug receptor interactions