HISTOPATHOLOGY FINAL EXAM
REVIEW 142 QUESTIONS & ANSWERS
RATED 100% CORRECT!!
1 of 140
Definition
Facilitate early folding and assembly
Stabilize maturing polypeptides, reduce risk of incorrect folding or
aggregation
Give this one a try later!
HSP normal role as
Maintenance of a steady state
chaperones
, Advantages or Formaldehyde The structure of compact bone
Don't know?
2 of 140
Definition
1. Pressure changes/abnormal metabolism
2. Autolysis (self digestion)
3. Putrefaction (decomposition)
Give this one a try later!
Disadvantages of alcohol Mechanisms of cell injury
3 types of tissue changes Removal of damaged proteins
can be seen Ubiquitin/ Proteosome System
Don't know?
3 of 140
Definition
- Formic, acetic and picric acid
- Formic acid used routinely at 5-10%, completes decalcification in
1- 10 days
- Use formic acid in combination w/formalin to allow for
,simultaneous fixation of the tissue and also buffers added to
counteract the damage to the tissue caused by acids
Give this one a try later!
Mechanisms of adaptation Weak acid decalcifiers
End Embedding
point testing
(a) impregnation
Don't know?
4 of 140
Definition
1. Cell stress response: emergency response
- always happens
- intermediate cellular response
2. Adaptive response: long term change
- doesn't always happen
- depends on severity/duration
Give this one a try later!
Physiological stimuli Pathological reduction in cell mass
Disadvantages of Pathological stimuli: how the
polyclonal antibodies cell responds
, Don't know?
5 of 140
Definition
Secondary antibodies
- Must recognize the primary antibody
- Normal serum used for blocking is taken from the same species
as the secondary antibody
eg.
* Monoclonal mouse anti-
human
* Secondary rabbit anti-
mouse (biotinlyated)
* Normal rabbit serum to
block
Give this one a try later!
Step 3 Two step indirect method
Step 6 Antigens
Don't know?
6 of 140
REVIEW 142 QUESTIONS & ANSWERS
RATED 100% CORRECT!!
1 of 140
Definition
Facilitate early folding and assembly
Stabilize maturing polypeptides, reduce risk of incorrect folding or
aggregation
Give this one a try later!
HSP normal role as
Maintenance of a steady state
chaperones
, Advantages or Formaldehyde The structure of compact bone
Don't know?
2 of 140
Definition
1. Pressure changes/abnormal metabolism
2. Autolysis (self digestion)
3. Putrefaction (decomposition)
Give this one a try later!
Disadvantages of alcohol Mechanisms of cell injury
3 types of tissue changes Removal of damaged proteins
can be seen Ubiquitin/ Proteosome System
Don't know?
3 of 140
Definition
- Formic, acetic and picric acid
- Formic acid used routinely at 5-10%, completes decalcification in
1- 10 days
- Use formic acid in combination w/formalin to allow for
,simultaneous fixation of the tissue and also buffers added to
counteract the damage to the tissue caused by acids
Give this one a try later!
Mechanisms of adaptation Weak acid decalcifiers
End Embedding
point testing
(a) impregnation
Don't know?
4 of 140
Definition
1. Cell stress response: emergency response
- always happens
- intermediate cellular response
2. Adaptive response: long term change
- doesn't always happen
- depends on severity/duration
Give this one a try later!
Physiological stimuli Pathological reduction in cell mass
Disadvantages of Pathological stimuli: how the
polyclonal antibodies cell responds
, Don't know?
5 of 140
Definition
Secondary antibodies
- Must recognize the primary antibody
- Normal serum used for blocking is taken from the same species
as the secondary antibody
eg.
* Monoclonal mouse anti-
human
* Secondary rabbit anti-
mouse (biotinlyated)
* Normal rabbit serum to
block
Give this one a try later!
Step 3 Two step indirect method
Step 6 Antigens
Don't know?
6 of 140
