Test bank for Basic and Clinical Pharmacology 15th Edition by
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Katzung
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test
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Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent,
and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a
disease. Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nurse is aware this drug has a high abuse potential. Under what category
would morphine be classified?
A) Schedule I
B) Schedule II
, Test bank for Basic and Clinical Pharmacology 15th Edition by
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Katzung
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C) Schedule III %gh
D) Schedule IV %gh
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II
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drugs because of severe dependence liability. Schedule I drugs have
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high abuse potential and no accepted medical use. Schedule III
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drugs have a lesser abuse potential than II and an accepted medical
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use. Schedule IV drugs have low abuse potential and limited
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dependence liability.
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3. When involved in phase III drug evaluation studies, what
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responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug
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study
C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in
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which patients are asked to record any symptoms they experience
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while taking the drugs. Nurses may be responsible for helping
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collect and analyze the information to be shared with the Food and
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Drug Administration (FDA) but would not conduct research
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independently because nurses do not prescribe medications. Use of
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animals in drug testing is done in the preclinical trials. Select
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patients who are involved in phase II studies to participate in
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studies where the participants have the disease the drug is intended
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to treat. These patients are monitored closely for drug action and
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adverse effects. Phase I studies involve healthy human volunteers
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who are usually paid for their participation. Nurses may observe for
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adverse effects and toxicity.
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4. What concept is considered when generic drugs are substituted for
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brand name drugs?
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A) Bioavailability
, Test bank for Basic and Clinical Pharmacology 15th Edition by
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Katzung
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B) Critical concentration %gh
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
systemic circulation and is available to act on body cells. Binders
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used in a generic drug may not be the same as those used in the
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brand name drug. Therefore, the way the body breaks down and
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uses the drug may differ, which may eliminate a generic drug
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substitution. Critical concentration is the amount of a drug that is
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needed to cause a therapeutic effect and should not differ between
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generic and brand name medications. Distribution is the phase of
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pharmacokinetics, which involves the movement of a drug to the
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bodys tissues and is the same in generic and brand name drugs. A
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drugs half-life is the time it takes for the amount of drug to
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decrease to half the peak level, which should not change when
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substituting a generic medication.
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5. A nurse is assessing the patients home medication use. After listening
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to the patient list current medications, the nurse asks what priority
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question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-
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counter medications because patients may not consider them
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important. The patient is unlikely to know the meaning of orphan
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drugs unless they too are health care providers. Safety during
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pregnancy, use of a generic medication, or classification of orphan
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drugs are things the patient would be unable to answer but could
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be found in reference books if the nurse wishes to research them.
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, Test bank for Basic and Clinical Pharmacology 15th Edition by
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Katzung
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6. After completing a course on pharmacology for nurses, what will the
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nurse know?
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A) Everything necessary for safe and effective medication
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administration
B) Current pharmacologic therapy; the nurse will not require
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ongoing education for 5 years.
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C) General drug information; the nurse can consult a drug guide for
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specific drug information.
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D) The drug actions that are associated with each
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classification of medication
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Ans: C
Feedback:
After completing a pharmacology course nurses will have general
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drug information needed for safe and effective medication
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administration but will need to consult a drug guide for specific drug
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information before administering any medication. Pharmacology is
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constantly changing, with new drugs entering the market and new
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uses for existing drugs identified.
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Continuing education in pharmacology is essential to safe practice.
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Nurses tend to become familiar with the medications they administer
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most often, but there will always be a need to research new drugs
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and also those the nurse is not familiar with because no nurse
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knows all medications.
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7. A nurse is instructing a pregnant patient concerning the potential risk
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to her fetus from a Pregnancy Category B drug. What would the
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nurse inform the patient?
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A) Adequate studies in pregnant women have demonstrated there is no
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risk to the fetus.
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B) Animal studies have not demonstrated a risk to the fetus, but
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there have been no adequate studies in pregnant women.
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C) Animal studies have shown an adverse effect on the fetus, but
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there are no adequate studies in pregnant women.
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D) There is evidence of human fetal risk, but the potential benefits
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from use of the drug may be acceptable despite potential
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risks.
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Ans: B
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Katzung
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test
%gh %gh %gh %gh %gh %gh %gh %gh
Bank
% g h
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent,
and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a
disease. Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nurse is aware this drug has a high abuse potential. Under what category
would morphine be classified?
A) Schedule I
B) Schedule II
, Test bank for Basic and Clinical Pharmacology 15th Edition by
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Katzung
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C) Schedule III %gh
D) Schedule IV %gh
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II
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drugs because of severe dependence liability. Schedule I drugs have
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high abuse potential and no accepted medical use. Schedule III
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drugs have a lesser abuse potential than II and an accepted medical
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use. Schedule IV drugs have low abuse potential and limited
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dependence liability.
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3. When involved in phase III drug evaluation studies, what
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responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug
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study
C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in
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which patients are asked to record any symptoms they experience
%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
while taking the drugs. Nurses may be responsible for helping
%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
collect and analyze the information to be shared with the Food and
%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
Drug Administration (FDA) but would not conduct research
%gh %gh %gh %gh %gh %gh %gh %gh
independently because nurses do not prescribe medications. Use of
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animals in drug testing is done in the preclinical trials. Select
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patients who are involved in phase II studies to participate in
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studies where the participants have the disease the drug is intended
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to treat. These patients are monitored closely for drug action and
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adverse effects. Phase I studies involve healthy human volunteers
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who are usually paid for their participation. Nurses may observe for
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adverse effects and toxicity.
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4. What concept is considered when generic drugs are substituted for
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brand name drugs?
%gh %gh %gh
A) Bioavailability
, Test bank for Basic and Clinical Pharmacology 15th Edition by
%gh %gh %gh %gh %gh %gh %gh %gh %gh
Katzung
%gh
B) Critical concentration %gh
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
systemic circulation and is available to act on body cells. Binders
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used in a generic drug may not be the same as those used in the
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brand name drug. Therefore, the way the body breaks down and
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uses the drug may differ, which may eliminate a generic drug
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substitution. Critical concentration is the amount of a drug that is
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needed to cause a therapeutic effect and should not differ between
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generic and brand name medications. Distribution is the phase of
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pharmacokinetics, which involves the movement of a drug to the
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bodys tissues and is the same in generic and brand name drugs. A
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drugs half-life is the time it takes for the amount of drug to
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decrease to half the peak level, which should not change when
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substituting a generic medication.
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5. A nurse is assessing the patients home medication use. After listening
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to the patient list current medications, the nurse asks what priority
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question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-
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counter medications because patients may not consider them
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important. The patient is unlikely to know the meaning of orphan
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drugs unless they too are health care providers. Safety during
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pregnancy, use of a generic medication, or classification of orphan
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drugs are things the patient would be unable to answer but could
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be found in reference books if the nurse wishes to research them.
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, Test bank for Basic and Clinical Pharmacology 15th Edition by
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Katzung
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6. After completing a course on pharmacology for nurses, what will the
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nurse know?
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A) Everything necessary for safe and effective medication
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administration
B) Current pharmacologic therapy; the nurse will not require
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ongoing education for 5 years.
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C) General drug information; the nurse can consult a drug guide for
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specific drug information.
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D) The drug actions that are associated with each
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classification of medication
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Ans: C
Feedback:
After completing a pharmacology course nurses will have general
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drug information needed for safe and effective medication
%gh %gh %gh %gh %gh %gh %gh %gh
administration but will need to consult a drug guide for specific drug
%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
information before administering any medication. Pharmacology is
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constantly changing, with new drugs entering the market and new
%gh %gh %gh %gh %gh %gh %gh %gh %gh %gh
uses for existing drugs identified.
%gh %gh %gh %gh %gh
Continuing education in pharmacology is essential to safe practice.
%gh %gh %gh %gh %gh %gh %gh %gh
Nurses tend to become familiar with the medications they administer
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most often, but there will always be a need to research new drugs
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and also those the nurse is not familiar with because no nurse
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knows all medications.
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7. A nurse is instructing a pregnant patient concerning the potential risk
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to her fetus from a Pregnancy Category B drug. What would the
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nurse inform the patient?
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A) Adequate studies in pregnant women have demonstrated there is no
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risk to the fetus.
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B) Animal studies have not demonstrated a risk to the fetus, but
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there have been no adequate studies in pregnant women.
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C) Animal studies have shown an adverse effect on the fetus, but
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there are no adequate studies in pregnant women.
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D) There is evidence of human fetal risk, but the potential benefits
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from use of the drug may be acceptable despite potential
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risks.
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Ans: B
