MIC 319 Exam 4 2025/2026 Exam
Questions and Correct Answers | New
Update
Extracellular pathogens can be: - 🧠 ANSWER ✔✔bacteria, viruses, fungi,
parasite
opsonization = - 🧠 ANSWER ✔✔coating of bacterium with antibody and/or
complement
What is the point of opsonization? - 🧠 ANSWER ✔✔To make the pathogen
more readily ingested by phagocytes
complement = - 🧠 ANSWER ✔✔collection of plasma proteins that act in a
cascade of reactions to attack extracellular forms of pathogens
cellular innate responses = - 🧠 ANSWER ✔✔neutrophil and macrophage
phagocytosis
Killing of microbes by cellular processes begins when? - 🧠 ANSWER
✔✔when they make contact with cells. This process continues within the
phagolysosome.
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,Neutrophils are stored in the __________ - 🧠 ANSWER ✔✔bone marrow
What are the 4 stages of extravasation of neutrophils: - 🧠 ANSWER ✔✔1.
Rolling adhesion via LFA and ICAM-1
2. Tight binding
3. Diapedesis
4. Migration along CXCL8 chemokine gradient
Receptor for complement? - 🧠 ANSWER ✔✔CD4
Receptor for LPS? - 🧠 ANSWER ✔✔CD14
Molecular innate response to extracellular bacteria? - 🧠 ANSWER
✔✔complement proteins
MAC refers to - 🧠 ANSWER ✔✔complement
PF referes to - 🧠 ANSWER ✔✔perforin
Who discovered P1 and P2 - 🧠 ANSWER ✔✔Dr. Podack
The killer domain of pore forming protein is the _____ domain - 🧠 ANSWER
✔✔MACPF
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, Extracellular batteria are killed by - 🧠 ANSWER ✔✔complement membrane
attack complex poly-C9
Virus infected cells are killed by - 🧠 ANSWER ✔✔P1
Intracellular bacteria are killed by - 🧠 ANSWER ✔✔P2
The last event of C9 is _______ - 🧠 ANSWER ✔✔making the hole in the
bacteria
Size of poly C-9 pore? - 🧠 ANSWER ✔✔110-120 A
The membrane attack complex is ____ - 🧠 ANSWER ✔✔C9
What proteins participate in the assembly of MAC? - 🧠 ANSWER ✔✔C5b,
C6, C7, C8, C9 (polymerization)
Innate immune system recognizes _______ - 🧠 ANSWER ✔✔PAMPs
PAMPs recognized by - 🧠 ANSWER ✔✔PRRs
Recognition of PAMP activates ________ - 🧠 ANSWER ✔✔complement
What is the most important "factor" of the complement process? - 🧠
ANSWER ✔✔C3
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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Questions and Correct Answers | New
Update
Extracellular pathogens can be: - 🧠 ANSWER ✔✔bacteria, viruses, fungi,
parasite
opsonization = - 🧠 ANSWER ✔✔coating of bacterium with antibody and/or
complement
What is the point of opsonization? - 🧠 ANSWER ✔✔To make the pathogen
more readily ingested by phagocytes
complement = - 🧠 ANSWER ✔✔collection of plasma proteins that act in a
cascade of reactions to attack extracellular forms of pathogens
cellular innate responses = - 🧠 ANSWER ✔✔neutrophil and macrophage
phagocytosis
Killing of microbes by cellular processes begins when? - 🧠 ANSWER
✔✔when they make contact with cells. This process continues within the
phagolysosome.
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
1
PRIVACY STATEMENT. ALL RIGHTS RESERVED
,Neutrophils are stored in the __________ - 🧠 ANSWER ✔✔bone marrow
What are the 4 stages of extravasation of neutrophils: - 🧠 ANSWER ✔✔1.
Rolling adhesion via LFA and ICAM-1
2. Tight binding
3. Diapedesis
4. Migration along CXCL8 chemokine gradient
Receptor for complement? - 🧠 ANSWER ✔✔CD4
Receptor for LPS? - 🧠 ANSWER ✔✔CD14
Molecular innate response to extracellular bacteria? - 🧠 ANSWER
✔✔complement proteins
MAC refers to - 🧠 ANSWER ✔✔complement
PF referes to - 🧠 ANSWER ✔✔perforin
Who discovered P1 and P2 - 🧠 ANSWER ✔✔Dr. Podack
The killer domain of pore forming protein is the _____ domain - 🧠 ANSWER
✔✔MACPF
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
2
PRIVACY STATEMENT. ALL RIGHTS RESERVED
, Extracellular batteria are killed by - 🧠 ANSWER ✔✔complement membrane
attack complex poly-C9
Virus infected cells are killed by - 🧠 ANSWER ✔✔P1
Intracellular bacteria are killed by - 🧠 ANSWER ✔✔P2
The last event of C9 is _______ - 🧠 ANSWER ✔✔making the hole in the
bacteria
Size of poly C-9 pore? - 🧠 ANSWER ✔✔110-120 A
The membrane attack complex is ____ - 🧠 ANSWER ✔✔C9
What proteins participate in the assembly of MAC? - 🧠 ANSWER ✔✔C5b,
C6, C7, C8, C9 (polymerization)
Innate immune system recognizes _______ - 🧠 ANSWER ✔✔PAMPs
PAMPs recognized by - 🧠 ANSWER ✔✔PRRs
Recognition of PAMP activates ________ - 🧠 ANSWER ✔✔complement
What is the most important "factor" of the complement process? - 🧠
ANSWER ✔✔C3
COPYRIGHT©BLAIRALISTERNEWTON 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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PRIVACY STATEMENT. ALL RIGHTS RESERVED
