Understanding Pathophysiology 6th Edition Huether Test Bank
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Test Bank for Huether and McCances Understanding
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, Understanding Pathophysiology 6th Edition Huether Test Bank gf gf gf gf gf gf
nd
Pathophysiology, Canadian, 2 Edition (Power-Kean, 2024),
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Chapter 1-42 | ALL Chapters gf gf gf gf gf
Chapter 01: Cellular Biology
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Huether & McCance: Understanding Pathophysiology, 6th Edition
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MULTIPLE CHOICE gf
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
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with histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
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b. A nucleus gf
c. Free-floating nuclear material gf gf
d. No organelles gf
ANS: B gf
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
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nucleus; thus, the nucleus should be observed. A single circular chromosome called a
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prokaryote contains free-floating nuclear material but has no organelles.
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REF: g f p. 2 gf
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
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describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
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a. Metabolic absorption gf
b. Communication
c. Secretion
d. Respiration
ANS: g f D
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
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involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
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secretion allows for the synthesizing of new substances.
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REF: g f p. 2 gf
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
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the genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm gf
ANS: C gf
The region of the cell that contains genetic material, including a large amount of ribonucleic
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acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
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the cell’s nucleus. Mitochondria is associated with cellular respiration, while ribosomes are
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involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
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cell.
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REF: g f p. 2 gf
, Understanding Pathophysiology 6th Edition Huether Test Bank gf gf gf gf gf gf
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
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layer itself?
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a. Peripheral membrane proteins gf gf
b. Integral membrane proteins gf gf
c. Glycoproteins
d. Cell adhesion molecules gf gf
ANS: B gf
Proteins directly attached to the membrane bilayer can be removed by the action of integral
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membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
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surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
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marks cells and does not float.
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REF: g f p. 7 gf
5. Which of the following can bind to plasma membrane receptors?
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a. Oxygen
b. Ribosomes
c. Amphipathic lipids gf
d. Ligands
ANS: D gf
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
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REF: g f p. 9 gf
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
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extracellular matrix would s uNp p oRr t t hIe dG
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gfsiC
s ofM
metastatic cancer? gf gf gf gf gf gf
gf gf gf
a. Decreased fibronectin gf
b. Increased collagen gf
c. Decreased elastin gf
d. Increased glycoproteins gf
ANS: A gf
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing
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them to travel or metastasize.
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REF: g f p. 10 gf
7. Which form of cell communication is used to relate to other cells in direct physical contact?
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a. Cell junction gf
b. Gap junction gf
c. Desmosome
d. Tight junction gf
ANS: A gf
Cell junctions hold cells together and permit molecules to pass from cell to cell.
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Gap junctions allow for cellular communication between cells. Neither desmosomes nor tight
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junctions are associated with cellular communication.
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REF: g f p. 11 gf
, Understanding Pathophysiology 6th Edition Huether Test Bank gf gf gf gf gf gf
8. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring
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alpha cells. This action is an example of which of the following signaling types?
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a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: A gf
Paracrine signaling involves the release of local chemical mediators that are quickly taken up,
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destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of
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glucagon. None of the other options involve signaling that is associated with a local
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chemical mediator like insulin.
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REF: g f p. 12
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9. In gf cellular metabolism, each enzyme has a high affinity for a:
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a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS: B gf
Each enzyme has a high affinity for a substrate, a specific substance converted to a product of
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the reaction. Cellular metabolism is not dependent on an attraction between an enzyme and
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any of the remaining options.
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REF: g f g f p. 16 gf
10. An athlete runs a marathon, after which his muscles feel fatigued and unable to contract. The
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athlete asks the nurse why this happened. The nurse’s response is based on the knowledge that
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the problem is result of a deficiency of:
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a. GTP
b. AMP
c. ATP
d. GMP
ANS: C gf
When ATP is deficient, impaired muscle contraction results. None of the other options are
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involved in muscle contraction.
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REF: g f p. 16
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11. Which phase of catabolism produces the most ATP?
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a. Digestion
b. Glycolysis
c. Oxidation
d. Citric acid cycle gf gf
ANS: D gf
While some ATP is produced during the oxidation and glycolysis phases, most of the ATP is
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generated during the citric acid cycle. Digestion does not produce any ATP.
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gf gf gf gf gf gf
Test Bank for Huether and McCances Understanding
gf gf gf gf gf gf gf
, Understanding Pathophysiology 6th Edition Huether Test Bank gf gf gf gf gf gf
nd
Pathophysiology, Canadian, 2 Edition (Power-Kean, 2024),
gf gf gf gf gf gf
Chapter 1-42 | ALL Chapters gf gf gf gf gf
Chapter 01: Cellular Biology
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Huether & McCance: Understanding Pathophysiology, 6th Edition
gf gf gf gf gf gf
MULTIPLE CHOICE gf
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
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with histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
gf gf gf
b. A nucleus gf
c. Free-floating nuclear material gf gf
d. No organelles gf
ANS: B gf
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
nucleus; thus, the nucleus should be observed. A single circular chromosome called a
gf gf gf gf gf gf gf gf gf gf gf gf gf
prokaryote contains free-floating nuclear material but has no organelles.
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REF: g f p. 2 gf
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
a. Metabolic absorption gf
b. Communication
c. Secretion
d. Respiration
ANS: g f D
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
gf gf gf gf gf gf gf gf gf gf gf gf
secretion allows for the synthesizing of new substances.
gf gf gf gf gf gf gf gf
REF: g f p. 2 gf
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
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the genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm gf
ANS: C gf
The region of the cell that contains genetic material, including a large amount of ribonucleic
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acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within
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the cell’s nucleus. Mitochondria is associated with cellular respiration, while ribosomes are
gf gf gf gf gf gf gf gf gf gf gf gf
involved with protein manufacturing. Cytoplasm is a fluid filling that is a component of the
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cell.
gf
REF: g f p. 2 gf
, Understanding Pathophysiology 6th Edition Huether Test Bank gf gf gf gf gf gf
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
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layer itself?
gf gf
a. Peripheral membrane proteins gf gf
b. Integral membrane proteins gf gf
c. Glycoproteins
d. Cell adhesion molecules gf gf
ANS: B gf
Proteins directly attached to the membrane bilayer can be removed by the action of integral
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membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the
gf gf gf gf gf gf gf gf gf gf gf gf
surface while cell adhesion molecules are on the outside of the membrane. Glycoprotein
gf gf gf gf gf gf gf gf gf gf gf gf gf
marks cells and does not float.
gf gf gf gf gf gf
REF: g f p. 7 gf
5. Which of the following can bind to plasma membrane receptors?
gf gf gf gf gf gf gf gf gf
a. Oxygen
b. Ribosomes
c. Amphipathic lipids gf
d. Ligands
ANS: D gf
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
REF: g f p. 9 gf
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
extracellular matrix would s uNp p oRr t t hIe dG
gf iagnBo.
gfsiC
s ofM
metastatic cancer? gf gf gf gf gf gf
gf gf gf
a. Decreased fibronectin gf
b. Increased collagen gf
c. Decreased elastin gf
d. Increased glycoproteins gf
ANS: A gf
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
them to travel or metastasize.
gf gf gf gf gf
REF: g f p. 10 gf
7. Which form of cell communication is used to relate to other cells in direct physical contact?
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
a. Cell junction gf
b. Gap junction gf
c. Desmosome
d. Tight junction gf
ANS: A gf
Cell junctions hold cells together and permit molecules to pass from cell to cell.
gf gf gf gf gf gf gf gf gf gf gf gf gf
Gap junctions allow for cellular communication between cells. Neither desmosomes nor tight
gf gf gf gf gf gf gf gf gf gf gf
junctions are associated with cellular communication.
gf gf gf gf gf gf
REF: g f p. 11 gf
, Understanding Pathophysiology 6th Edition Huether Test Bank gf gf gf gf gf gf
8. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring
gf gf gf gf gf gf gf gf gf gf gf
alpha cells. This action is an example of which of the following signaling types?
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: A gf
Paracrine signaling involves the release of local chemical mediators that are quickly taken up,
gf gf gf gf gf gf gf gf gf gf gf gf gf
destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
glucagon. None of the other options involve signaling that is associated with a local
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
chemical mediator like insulin.
gf gf gf gf
REF: g f p. 12
gf
9. In gf cellular metabolism, each enzyme has a high affinity for a:
gf gf gf gf gf gf gf gf gf
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS: B gf
Each enzyme has a high affinity for a substrate, a specific substance converted to a product of
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
the reaction. Cellular metabolism is not dependent on an attraction between an enzyme and
gf gf gf gf gf gf gf gf gf gf gf gf gf gf
any of the remaining options.
gf gf gf gf gf
REF: g f g f p. 16 gf
10. An athlete runs a marathon, after which his muscles feel fatigued and unable to contract. The
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
athlete asks the nurse why this happened. The nurse’s response is based on the knowledge that
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
the problem is result of a deficiency of:
gf gf gf gf gf gf gf gf
a. GTP
b. AMP
c. ATP
d. GMP
ANS: C gf
When ATP is deficient, impaired muscle contraction results. None of the other options are
gf gf gf gf gf gf gf gf gf gf gf gf gf
involved in muscle contraction.
gf gf gf gf
REF: g f p. 16
gf
11. Which phase of catabolism produces the most ATP?
gf gf gf gf gf gf gf
a. Digestion
b. Glycolysis
c. Oxidation
d. Citric acid cycle gf gf
ANS: D gf
While some ATP is produced during the oxidation and glycolysis phases, most of the ATP is
gf gf gf gf gf gf gf gf gf gf gf gf gf gf gf
generated during the citric acid cycle. Digestion does not produce any ATP.
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