Test Bank for Pathophysiology: A Practical Approach 4th Edition – 100% Verified with Rationales | 2025 Update

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,Contents
📝 Chapter 1: Cellular Function .................................................................... 3
📝 Chapter 2: Immunity ............................................................................. 13
📝 Chapter 3: Hematopoietic Function...................................................... 24
📝 Chapter 4: Cardiovascular Function ...................................................... 34
📝 Chapter 5: Respiratory Function ........................................................... 46
📝 Chapter 6: Fluid, Electrolyte, and Acid-Base Homeostasis ................... 57
📝 Chapter 7: Urinary Function ................................................................. 69
📝 Chapter 8: Reproductive Function ........................................................ 79
📝 Chapter 9: Gastrointestinal Function.................................................... 90
📝 Chapter 10: Endocrine Function ......................................................... 101
📝 Chapter 11: Neural Function ............................................................... 113
📝 Chapter 12: Musculoskeletal Function ............................................... 124
📝 Chapter 13: Integumentary Function.................................................. 134
📝 Chapter 14: Sensory Function ............................................................. 143




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,📝 Chapter 1: Cellular Function


1. Which of the following best describes the primary function of the
mitochondria within a cell?
A. Protein synthesis
B. DNA replication
C. Energy production through ATP
D. Detoxification of chemicals
✅ Correct Answer: C. Energy production through ATP
💡 Rationale: Mitochondria are known as the "powerhouses" of the cell.
They generate adenosine triphosphate (ATP) through oxidative
phosphorylation, which is critical for cellular energy needs. While other
organelles play roles in protein synthesis (ribosomes), DNA replication
(nucleus), and detoxification (smooth ER), mitochondria’s chief role is
energy production.



2. Which cellular transport mechanism requires energy and moves
substances against their concentration gradient?
A. Facilitated diffusion
B. Simple diffusion
C. Osmosis
D. Active transport
✅ Correct Answer: D. Active transport
💡 Rationale: Active transport requires ATP to move substances from
areas of lower concentration to higher concentration—against the gradient.
The sodium-potassium pump is a classic example. In contrast, osmosis and
diffusion are passive and do not require energy.



3. What is the primary role of lysosomes in cellular physiology?
A. Protein folding
B. Lipid synthesis
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, C. Intracellular digestion
D. Energy storage
✅ Correct Answer: C. Intracellular digestion
💡 Rationale: Lysosomes contain hydrolytic enzymes that digest excess or
worn-out organelles, food particles, and engulfed viruses or bacteria. They
are essential for cellular waste management and recycling processes.



4. Which phase of the cell cycle is primarily associated with DNA
synthesis?
A. G1 phase
B. S phase
C. G2 phase
D. M phase
✅ Correct Answer: B. S phase
💡 Rationale: The S (synthesis) phase of interphase is when DNA
replication occurs. The G1 and G2 phases are periods of cell growth and
preparation for division, while the M phase (mitosis) involves actual cell
division.



5. A cell exposed to hypoxia is most likely to undergo which of the
following changes?
A. Hyperplasia
B. Atrophy
C. Apoptosis
D. Hypertrophy
✅ Correct Answer: B. Atrophy
💡 Rationale: Hypoxia, or a lack of oxygen, leads to decreased cellular
metabolism and energy production. This reduction in activity typically results
in atrophy, or a decrease in cell size and function.




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