ABFM KSA DEPRESSION EXAM WITH
CORRECT ANSWERS 2025
Antidepressants that should be avoided in patients taking CYP 450
metabolized drugs. ( Correct answers ) Paroxetine and Fluoxetine (inhibits
CYP2D6)
(T/F) Postpartum patients with postpartum depression can take
antidepressants when breastfeeding ( Correct answers ) True
(T/F)SRRI used in third trimester has bene linked to persistent
pulmonary HTN of newborn ( Correct answers ) True
Which medications are approved by FDA for tx of mania in patients with
bipolar disorder? ( Correct answers ) Lithium, Chlorpromazine, Divalproex,
and Antipsychotics (Olanzapine, and Risperidone)
Which medications are approved by FDA for tx of patients with bipolar
depression? ( Correct answers ) Quetiapine, Lurasidone, and
Olanzapine/Fluoxetine
What elements support a Dx of MDD with atypical features? ( Correct
answers ) Presence of marked mood reactivity (improvement in mood in
response to actual/potential positive events) and 2 or more: weight gain,
increase appetie, hypersomnia, leaden paralysis, and a long standing
pattern of interpersonal rejection sensitivity.
Best drugs in a MDD patient who wants to quit smoking. ( Correct answers )
Bupropion (Wellbutrin) and Nortriptyline (Pamelor)
Best drugs in a Parkinson's patient with MDD. ( Correct answers ) SNRIs
(Venlafaxine, duloxetine, or desvenlafaxine) and noradrenergic agents
(desipramine)
Effects of serotonin syndrome ( Correct answers ) Hyperthermia, HTN,
tachycardia, and tachypnea. Dilated Pupils, hyperreflexia and clonus.
Effects of NMS ( Correct answers ) Hyperthermia, HTN, tachycardia, and
tachypnea. Diaphoresis, sialorrhea, "Lead Pipe" rigidity, reduced reflexes.
CORRECT ANSWERS 2025
Antidepressants that should be avoided in patients taking CYP 450
metabolized drugs. ( Correct answers ) Paroxetine and Fluoxetine (inhibits
CYP2D6)
(T/F) Postpartum patients with postpartum depression can take
antidepressants when breastfeeding ( Correct answers ) True
(T/F)SRRI used in third trimester has bene linked to persistent
pulmonary HTN of newborn ( Correct answers ) True
Which medications are approved by FDA for tx of mania in patients with
bipolar disorder? ( Correct answers ) Lithium, Chlorpromazine, Divalproex,
and Antipsychotics (Olanzapine, and Risperidone)
Which medications are approved by FDA for tx of patients with bipolar
depression? ( Correct answers ) Quetiapine, Lurasidone, and
Olanzapine/Fluoxetine
What elements support a Dx of MDD with atypical features? ( Correct
answers ) Presence of marked mood reactivity (improvement in mood in
response to actual/potential positive events) and 2 or more: weight gain,
increase appetie, hypersomnia, leaden paralysis, and a long standing
pattern of interpersonal rejection sensitivity.
Best drugs in a MDD patient who wants to quit smoking. ( Correct answers )
Bupropion (Wellbutrin) and Nortriptyline (Pamelor)
Best drugs in a Parkinson's patient with MDD. ( Correct answers ) SNRIs
(Venlafaxine, duloxetine, or desvenlafaxine) and noradrenergic agents
(desipramine)
Effects of serotonin syndrome ( Correct answers ) Hyperthermia, HTN,
tachycardia, and tachypnea. Dilated Pupils, hyperreflexia and clonus.
Effects of NMS ( Correct answers ) Hyperthermia, HTN, tachycardia, and
tachypnea. Diaphoresis, sialorrhea, "Lead Pipe" rigidity, reduced reflexes.
