PRITE 2025 LATEST UPDATE
What neurochemical abnormality is most consistently described in Alzheimer disease of
moderate severity. - ANSWER Decreased choline acetyltransferase activity
Which of the following sources of pain is thought to have a primarily central (non-
nociceptive) mechanism?
a) cancer pain
b) fibromyalgia
c) osteoarthritis
d) diabetic neuropathy
e) postherpetic neuralgia - ANSWER b) fibromyalgia
A patient presents with mild memory impairment, tearfulness, insomnia, and blurry
vision. The patient acts as if blind, cannot locate objects in the visual field, has left-right
disorientation and alexia, and misses objects when instructed to reach for them. The
patient only identifies a single object in a drawing of overlapping objects. Despite
requiring prompts to visually follow objects, cranial nerves, motor function, reflexes, and
movement and color detection are otherwise intact. What is the most likely cause of the
visual disturbance? - ANSWER Cerebral infarct
Variable phenotypic expression of 15q13 deletion depends on whether the encoding
gene is
derived from the father or the mother. This phenomenon is commonly referred to as -
ANSWER Genomic imprinting
A patient hospitalized for burns sustained in a house fire one week prior is experiencing
recurrent nightmares and frequent, intrusive memories about the fire accompanied by
concern that the patient seems depressed, is sleeping poorly and startles when
someone enters the room without knocking. On exam, the patient is distracted,
sometimes irritable, and has labile affect. What is the most likely diagnosis? - ANSWER
Acute stress disorder
What is an example of epigenetic gene regulation? - ANSWER Addition of methyl group
to a histone around which DNA is coiled.
What sex hormone is most responsible for sexual differentiation in fetal brain
development? - ANSWER Testosterone (causes brain/body to be masculinized and
defeminized)
What psychiatric disorder occurs most frequently with secondary enuresis? - ANSWER
ADHD
,The psychiatrist is concerned about a colleague's behavior and notifies the State's
physician health program, which conducts an intervention. The physician should be
referred for professional evaluation/treatment in which scenario?
A) drinks wine with diner
B) has experienced depression and been hospitalized in past
C) has bipolar disorder and is euthymic/med compliant
D) uses cocaine occasionally but not habitually, on days off, negative utox
E) aggressive toward patients on 3 different occasions during ED shifts - ANSWER E
Abnormalities in which of the following components of the neurological examination
would indicate cerebellar dysfunction? - ANSWER Rapid alternating movements
Excessive activation of which of the following receptors is thought to contribute to cell
death in Alzheimer disease? - ANSWER NMDA
In behavior mastery training, which of the following techniques teaches individuals with
sexual addiction to identify factors that increase the likelihood of symptomatic sexual
behavior? - ANSWER Risk management
A patient has been prescribed a second-gen antipsychotic for just over a year. Since
starting the medication, her libido is markedly lower, and she has experienced irregular
menstrual cycles. Which lab test would have greatest diagnostic value at this point? -
ANSWER Prolactin
A 58 year old patient develops progressive weakness and tingling two weeks after
receiving a vaccination. Examination reveals weakness and decreased sensation in the
legs, as well as absent DTRs in arms and legs. Imaging of the brain and spine is
normal. Which test will confirm the most likely diagnosis? - ANSWER Nerve conduction
studies
Which of the following is among the first steps taken by a public school to address a
student's difficulty being successful academically? - ANSWER Initiate a response to
intervention plan
Which of the following nuclei of the hypothalamus is the major site for Neuropeptide Y
synthesis? - ANSWER Arcuate nucleus
Which type of group therapy encourages high intragroup dependence and less group
leader dependence? - ANSWER Transactional
Which mechanism is the most likely cause of anosmia in patients infected with
COVID19? - ANSWER Direct viral involvement of the nasal epithelium
, An argumentative 10 year old who displays persistent anger outbursts, vindictiveness,
and deliberately annoys adults most likely has what disorder? - ANSWER Oppositional
defiant disorder
What outcome has been demonstrated to improve as a result of peer support services
in the treatment of people with mental illness? - ANSWER Social functioning
Electroconvulsive therapy is indicated for which of the following conditions?
A) Dissociative fugue
B) Serotonin syndrome
C) Intermittent explosive disorder
D) OCD
E) NMS - ANSWER E) NMS
Which white matter tracts connects the temporal and orbitofrontal cortices? - ANSWER
Uncinate fasiculus
Cingulum - ANSWER Connects frontal, temporal, and parietal lobes and also
subcortical nuclei to cingulate gyrus
Arcuate fasiculus - ANSWER Connects Wernicke's and Brocas
Inferior longitudinal fasciculus - ANSWER Connects occipital and temporal lobes
Superior longitudinal fasciculus - ANSWER Connects frontal lobe and ipsilateral
hemisphere
The Clinical Pharmacogenetics Implementation Consortium dosing guidelines for
antidepressants are based on genetic variations in _______. - ANSWER CYP450
enzymes
Which molecular mechanism is best supported as a possible explanation for how early
life stress could lead to the development of psychiatric disorders in adulthood? -
ANSWER DNA methylation
Postpartum depression has been consistently associated with which outcome in
children? - ANSWER Infant growth impairment
A patient is convinced that their boss hates them, despite objective evidence to the
contrary. The patient's belief is best described by which defense mechanism? -
ANSWER Projection
(attributing one's own unacceptable thoughts/feelings/motives onto another person)
Denial - ANSWER Blocking external events from awareness
What neurochemical abnormality is most consistently described in Alzheimer disease of
moderate severity. - ANSWER Decreased choline acetyltransferase activity
Which of the following sources of pain is thought to have a primarily central (non-
nociceptive) mechanism?
a) cancer pain
b) fibromyalgia
c) osteoarthritis
d) diabetic neuropathy
e) postherpetic neuralgia - ANSWER b) fibromyalgia
A patient presents with mild memory impairment, tearfulness, insomnia, and blurry
vision. The patient acts as if blind, cannot locate objects in the visual field, has left-right
disorientation and alexia, and misses objects when instructed to reach for them. The
patient only identifies a single object in a drawing of overlapping objects. Despite
requiring prompts to visually follow objects, cranial nerves, motor function, reflexes, and
movement and color detection are otherwise intact. What is the most likely cause of the
visual disturbance? - ANSWER Cerebral infarct
Variable phenotypic expression of 15q13 deletion depends on whether the encoding
gene is
derived from the father or the mother. This phenomenon is commonly referred to as -
ANSWER Genomic imprinting
A patient hospitalized for burns sustained in a house fire one week prior is experiencing
recurrent nightmares and frequent, intrusive memories about the fire accompanied by
concern that the patient seems depressed, is sleeping poorly and startles when
someone enters the room without knocking. On exam, the patient is distracted,
sometimes irritable, and has labile affect. What is the most likely diagnosis? - ANSWER
Acute stress disorder
What is an example of epigenetic gene regulation? - ANSWER Addition of methyl group
to a histone around which DNA is coiled.
What sex hormone is most responsible for sexual differentiation in fetal brain
development? - ANSWER Testosterone (causes brain/body to be masculinized and
defeminized)
What psychiatric disorder occurs most frequently with secondary enuresis? - ANSWER
ADHD
,The psychiatrist is concerned about a colleague's behavior and notifies the State's
physician health program, which conducts an intervention. The physician should be
referred for professional evaluation/treatment in which scenario?
A) drinks wine with diner
B) has experienced depression and been hospitalized in past
C) has bipolar disorder and is euthymic/med compliant
D) uses cocaine occasionally but not habitually, on days off, negative utox
E) aggressive toward patients on 3 different occasions during ED shifts - ANSWER E
Abnormalities in which of the following components of the neurological examination
would indicate cerebellar dysfunction? - ANSWER Rapid alternating movements
Excessive activation of which of the following receptors is thought to contribute to cell
death in Alzheimer disease? - ANSWER NMDA
In behavior mastery training, which of the following techniques teaches individuals with
sexual addiction to identify factors that increase the likelihood of symptomatic sexual
behavior? - ANSWER Risk management
A patient has been prescribed a second-gen antipsychotic for just over a year. Since
starting the medication, her libido is markedly lower, and she has experienced irregular
menstrual cycles. Which lab test would have greatest diagnostic value at this point? -
ANSWER Prolactin
A 58 year old patient develops progressive weakness and tingling two weeks after
receiving a vaccination. Examination reveals weakness and decreased sensation in the
legs, as well as absent DTRs in arms and legs. Imaging of the brain and spine is
normal. Which test will confirm the most likely diagnosis? - ANSWER Nerve conduction
studies
Which of the following is among the first steps taken by a public school to address a
student's difficulty being successful academically? - ANSWER Initiate a response to
intervention plan
Which of the following nuclei of the hypothalamus is the major site for Neuropeptide Y
synthesis? - ANSWER Arcuate nucleus
Which type of group therapy encourages high intragroup dependence and less group
leader dependence? - ANSWER Transactional
Which mechanism is the most likely cause of anosmia in patients infected with
COVID19? - ANSWER Direct viral involvement of the nasal epithelium
, An argumentative 10 year old who displays persistent anger outbursts, vindictiveness,
and deliberately annoys adults most likely has what disorder? - ANSWER Oppositional
defiant disorder
What outcome has been demonstrated to improve as a result of peer support services
in the treatment of people with mental illness? - ANSWER Social functioning
Electroconvulsive therapy is indicated for which of the following conditions?
A) Dissociative fugue
B) Serotonin syndrome
C) Intermittent explosive disorder
D) OCD
E) NMS - ANSWER E) NMS
Which white matter tracts connects the temporal and orbitofrontal cortices? - ANSWER
Uncinate fasiculus
Cingulum - ANSWER Connects frontal, temporal, and parietal lobes and also
subcortical nuclei to cingulate gyrus
Arcuate fasiculus - ANSWER Connects Wernicke's and Brocas
Inferior longitudinal fasciculus - ANSWER Connects occipital and temporal lobes
Superior longitudinal fasciculus - ANSWER Connects frontal lobe and ipsilateral
hemisphere
The Clinical Pharmacogenetics Implementation Consortium dosing guidelines for
antidepressants are based on genetic variations in _______. - ANSWER CYP450
enzymes
Which molecular mechanism is best supported as a possible explanation for how early
life stress could lead to the development of psychiatric disorders in adulthood? -
ANSWER DNA methylation
Postpartum depression has been consistently associated with which outcome in
children? - ANSWER Infant growth impairment
A patient is convinced that their boss hates them, despite objective evidence to the
contrary. The patient's belief is best described by which defense mechanism? -
ANSWER Projection
(attributing one's own unacceptable thoughts/feelings/motives onto another person)
Denial - ANSWER Blocking external events from awareness
