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."P" value - ANSWER-probability of observing a result as extreme as or
more extreme than the one actually observed from chance alone.
."z" test - ANSWER-statistical test for comparing a mean with a norm
or comparing two means for large samples (30 or above).
.A.A - ANSWER-medication dosage "of each.
.A.C - ANSWER-medication dosage "before meals"
.a(=intercept constant) - ANSWER-point at which the regression line
intercepts the y-axis.
.absolute value - ANSWER-positive value of a number, regardless of
whether the number is positive or negative. absolute value of "a" is
symbolized as lal.
,.absorption - ANSWER-how the drug passes from its site of
administration into the bloodstream.
.absorption rate - ANSWER-rate at which a drug is taken into a
person's bloodstream within a specified time period.
.abstract concept - ANSWER-starting point for measurement, abstract
concept is best understood as a general idea in linguistic form that
helps us describe reality.
.AC - ANSWER-anticholinergic side effects (ex. dry mouth, blurred
vision).
.academy of managed care pharmacy (AMCP) - ANSWER-organization
for pharmacy directors.
.accelerated approval - ANSWER-specialized FDA mechanism
implemented in the early 1990's to speed approval of drugs that
represent a major advance in addressing serious or life-threatening
diseases for which no effective alternative treatment exist.
.ACE inhibitors - ANSWER-angiotensin-converting enzyme inhibitors.
class of drugs to treat cardiovascular conditions.
,.action letter - ANSWER-FDA's official response to NDA.
.active metabolite - ANSWER-biological active product of a
medication's metabolism.
.active pharmaceutical ingredient (API) - ANSWER-part of a drug
formulation that is responsible for achieving a therapeutic effect.
.actue illness - ANSWER-condition or illness that only lasts for a short
period of time.
.acute - ANSWER-disease is short.
.AD. LIB - ANSWER-medication dosage "freely"
.addition rule - ANSWER-the probability that two or more mutually
exclusive events that occur are the sum of the probabilities of each
individual event.
.additions - ANSWER-situations where two or more medications are
used together and the clinical effect is equal to the sum of their
individual effects.
.adherence - ANSWER-proper use of a medication by a patient.
, .adjuvant - ANSWER-substance that enhances the action of a drug or
antigen.
.ADME - ANSWER-acronym for absorption, distribution, metabolism,
and excretion.
.ADME testing - ANSWER-measures the rate at which the body
absorbs the drug, distributes it to the organs necessary to produce the
desired effect, metabolizes it into waste material and then excretes it
from the body.
.adverse drug reaction - ANSWER-unwanted reaction.
.adverse effect - ANSWER-unwanted effect a medication may have on
a person.
.adverse event - ANSWER-unanticipated event that involves risk to
the subject and that results in harm to the subject or others.
.adverse reactions - ANSWER-any unexpected or dangerous reaction
to a drug.
.aerosols - ANSWER-are frequently delivered by oral inhalers or
nebulizers that allow for rapid absorption into the blood circulation.