Med Tech Final Exam 382 Questions with Verified Answers
Study of the immune system
- began as a study of infectious disease - CORRECT ANSWER Immunology
Components of the Paramyxoviruses (RSV) : (6) - CORRECT ANSWER (1) HH/H/G
glycoprotein spikes
(2) F glycoprotein spikes
(3)Helical nucelocapsid (RNA plus NP protein)
(4)Lipid bilayer membrane
(5) Polymerase (2 proteins)
The ___________________ system is fundamental to good health - CORRECT
ANSWER immune
In waht two cases can the immune system cuse disease? (2) - CORRECT ANSWER
(1) Allergies
(2) Autoimmune disease
These Immunological-based Assays are used in all laboratory departments: (6) -
CORRECT ANSWER (1) Disease diagnosis
(2) Identify microorganisms
(3) Type blood and tissue
(4) Identify Cells
(5) Detect nonimmunological function
(6) Evaluate immune function
The immune system is ____________ - has many functions - CORRECT ANSWER
complex
There are the modes of natural resistant (nonspecific) in immune response: (5) -
CORRECT ANSWER (1) Physical barriers (skin, nails)
(2) Secretions
(3) Phagocytes
,(4) Inflammation
(5) Natural biochemicals (histamine, heparin, opsin)
Basophils/Mastt cells secret these these item during the inflammatory response -
CORRECT ANSWER granules and histamine
Why is heparin released? - CORRECT ANSWER Allow the phagocyte to flow easier
Whta is the inflammatory function of histamine? - CORRECT ANSWER It calms
down the inflammation
3 Components of specific immunity: - CORRECT ANSWER (1) Recognition
(2) Specificity
(3) Memory - anamnestic reponse
What are the main cells, tissues and organs involved in the immune response? -
CORRECT ANSWER T and B cells
Primary lymphoid organs
Secondary Lymphoid tissue
These are the primary lymphoid organs - CORRECT ANSWER Bone marrow
Thymus
These are the secondary lymphoid tissues: - CORRECT ANSWER Spleen
Lymph nodes
Tonsils
When we talk about humoral immunity, we are referring to the action of
___________________. - CORRECT ANSWER antibodies
What cells are involved in humoral immunity? - CORRECT ANSWER B Lymphocytes
Plasma cells
Antibodies
Humoral immunity is effective against - CORRECT ANSWER toxins and most
bacteria
,___________________________ are effective and specificWhat cells are inovlved
in cell-medited immunity? ; they only bind to a specific ntigen - CORRECT ANSWER
T Lymphocytes
Macrophages
Cytokines/Lymphokines
Cell mediated immunity is effective against: - CORRECT ANSWER Viruses
Intracellular organisms
Tumor cells
What are the 2 subset sof T Lymphocytes? - CORRECT ANSWER (1) CD4 (+) helper
cells
(2) CD8 (+) cytotoxic cells
HIV destroys these cells - CORRECT ANSWER CD4 + cells
- people don't die from the virus
- they die from the secondary infections that they cannot fight off
Immunoglobulins have (2) - CORRECT ANSWER (1) Epitope-binding site
(2) Heavy and light chains
What two fragments make up the immunoglobulin? - CORRECT ANSWER (1) Fab
(2) Fc
This fragment of the Ab can change based on what you are looking for - CORRECT
ANSWER Fab
This fragment of the Ab is a part of the constant region; doesn't change -
CORRECT ANSWER Fc
What are the 5 classes of IG? - CORRECT ANSWER (1) IgG
(2) IgM
(3) IgA
(4) IgD
(5) IgE
What are the 2 main immunoglobulins - CORRECT ANSWER IgG and IgM
, Describe the primary immune response and what immunoglobulins are secreted.
- CORRECT ANSWER (1) First Ag exposure
(2) First Ab made are IgM ==> 10 binding sites because pentavalent
(3) levels of IgM taper off as the titer goes down
Describe the secondary immune response and what immunoglobulins are
secreted. - CORRECT ANSWER (1) IgG is made in greater amounts
(2) Still produce some IgM
Name 4 diseases of the immune system: - CORRECT ANSWER (1) Allergies
(2) Autoimmune disease
(3) Inherited or congenital problems
(4) Malignancies
- lymphoma
- leukemia
Immunological tests are based on these reactions - CORRECT ANSWER Ag-Ab
reactions
_______________________ antibodies are found from multiple sources -
CORRECT ANSWER polyclonal
________________________ antibodies are isolated from a single source -
CORRECT ANSWER monoclonal
Ag-Ab reactions test for - CORRECT ANSWER sensitivity ad specificity
3 specificities for immunological testing - CORRECT ANSWER (1) Qualitative
(Yes/No)
(2) Semi-qualitative (range between 150-300)
(3) Quantitative (specific # >5)
This type of Ag-Ab test looks for Ab + particulate Ag - CORRECT ANSWER
Agglutination
- we're looking for an Ab
- when Ag mixes with Ab they will bind
Study of the immune system
- began as a study of infectious disease - CORRECT ANSWER Immunology
Components of the Paramyxoviruses (RSV) : (6) - CORRECT ANSWER (1) HH/H/G
glycoprotein spikes
(2) F glycoprotein spikes
(3)Helical nucelocapsid (RNA plus NP protein)
(4)Lipid bilayer membrane
(5) Polymerase (2 proteins)
The ___________________ system is fundamental to good health - CORRECT
ANSWER immune
In waht two cases can the immune system cuse disease? (2) - CORRECT ANSWER
(1) Allergies
(2) Autoimmune disease
These Immunological-based Assays are used in all laboratory departments: (6) -
CORRECT ANSWER (1) Disease diagnosis
(2) Identify microorganisms
(3) Type blood and tissue
(4) Identify Cells
(5) Detect nonimmunological function
(6) Evaluate immune function
The immune system is ____________ - has many functions - CORRECT ANSWER
complex
There are the modes of natural resistant (nonspecific) in immune response: (5) -
CORRECT ANSWER (1) Physical barriers (skin, nails)
(2) Secretions
(3) Phagocytes
,(4) Inflammation
(5) Natural biochemicals (histamine, heparin, opsin)
Basophils/Mastt cells secret these these item during the inflammatory response -
CORRECT ANSWER granules and histamine
Why is heparin released? - CORRECT ANSWER Allow the phagocyte to flow easier
Whta is the inflammatory function of histamine? - CORRECT ANSWER It calms
down the inflammation
3 Components of specific immunity: - CORRECT ANSWER (1) Recognition
(2) Specificity
(3) Memory - anamnestic reponse
What are the main cells, tissues and organs involved in the immune response? -
CORRECT ANSWER T and B cells
Primary lymphoid organs
Secondary Lymphoid tissue
These are the primary lymphoid organs - CORRECT ANSWER Bone marrow
Thymus
These are the secondary lymphoid tissues: - CORRECT ANSWER Spleen
Lymph nodes
Tonsils
When we talk about humoral immunity, we are referring to the action of
___________________. - CORRECT ANSWER antibodies
What cells are involved in humoral immunity? - CORRECT ANSWER B Lymphocytes
Plasma cells
Antibodies
Humoral immunity is effective against - CORRECT ANSWER toxins and most
bacteria
,___________________________ are effective and specificWhat cells are inovlved
in cell-medited immunity? ; they only bind to a specific ntigen - CORRECT ANSWER
T Lymphocytes
Macrophages
Cytokines/Lymphokines
Cell mediated immunity is effective against: - CORRECT ANSWER Viruses
Intracellular organisms
Tumor cells
What are the 2 subset sof T Lymphocytes? - CORRECT ANSWER (1) CD4 (+) helper
cells
(2) CD8 (+) cytotoxic cells
HIV destroys these cells - CORRECT ANSWER CD4 + cells
- people don't die from the virus
- they die from the secondary infections that they cannot fight off
Immunoglobulins have (2) - CORRECT ANSWER (1) Epitope-binding site
(2) Heavy and light chains
What two fragments make up the immunoglobulin? - CORRECT ANSWER (1) Fab
(2) Fc
This fragment of the Ab can change based on what you are looking for - CORRECT
ANSWER Fab
This fragment of the Ab is a part of the constant region; doesn't change -
CORRECT ANSWER Fc
What are the 5 classes of IG? - CORRECT ANSWER (1) IgG
(2) IgM
(3) IgA
(4) IgD
(5) IgE
What are the 2 main immunoglobulins - CORRECT ANSWER IgG and IgM
, Describe the primary immune response and what immunoglobulins are secreted.
- CORRECT ANSWER (1) First Ag exposure
(2) First Ab made are IgM ==> 10 binding sites because pentavalent
(3) levels of IgM taper off as the titer goes down
Describe the secondary immune response and what immunoglobulins are
secreted. - CORRECT ANSWER (1) IgG is made in greater amounts
(2) Still produce some IgM
Name 4 diseases of the immune system: - CORRECT ANSWER (1) Allergies
(2) Autoimmune disease
(3) Inherited or congenital problems
(4) Malignancies
- lymphoma
- leukemia
Immunological tests are based on these reactions - CORRECT ANSWER Ag-Ab
reactions
_______________________ antibodies are found from multiple sources -
CORRECT ANSWER polyclonal
________________________ antibodies are isolated from a single source -
CORRECT ANSWER monoclonal
Ag-Ab reactions test for - CORRECT ANSWER sensitivity ad specificity
3 specificities for immunological testing - CORRECT ANSWER (1) Qualitative
(Yes/No)
(2) Semi-qualitative (range between 150-300)
(3) Quantitative (specific # >5)
This type of Ag-Ab test looks for Ab + particulate Ag - CORRECT ANSWER
Agglutination
- we're looking for an Ab
- when Ag mixes with Ab they will bind
