NURS 7430 Advanced Pharm - Exam 1
questions well answered to pass
Pharmacokinetics - correct answer ✔✔The process by which drugs are absorbed,
distributed within the body, metabolized, and excreted.
Pharmacodynamics - correct answer ✔✔The process by which a medication works
on the body.
Pharmacogenomics - correct answer ✔✔The study of how genetic inheritance
affects the body's response to drugs
What is the role of lipid-soluble, hydrophilic drugs, and simple diffusion in getting
medications into cells? - correct answer ✔✔
Explain the concept of drug: potency, efficacy, side-effect, onset of action,
minimum effective concentration, peak level, therapeutic range, duration of
action, therapeutic index, therapeutic effect, mechanism of action, and steady
state. - correct answer ✔✔
Four processes involved when a drug is taken: - correct answer ✔✔1. absorption
2. distribution
3. metabolism
4. elimination/excretion
, Explain the relationship of the Brain-blood barrier in pharmacodynamics of
medications. - correct answer ✔✔Blood vessels (capillaries) selectively let certain
substances enter the brain tissue and keep other substances out. uses only lipid
soluble or transport system
What determines the degree of movement of a drug between body
compartments? - correct answer ✔✔1. degree of hydrophila
2. degree lipophilicity
3. molecular weight
Define and explain the purpose of synergistic antibiotic combination of antibiotics.
Give examples of this practice. - correct answer ✔✔Abx that work in tandem to
increase efficacy.
Ex: amoxicillin + clavulanic acid (Augmentin) or piperacillin + tazobactam (Zosyn)
Explain why Clavulanic acid is added to amoxicillin. - correct answer ✔✔to make it
more effective against bacteria that produce beta lactamase
Explain the risk of prolonged QT syndrome and torsade de pointes and give
examples of medications that may cause this problem. - correct answer
✔✔Macrolides (azithromycin, clarithromycin, erythromycin)
What would be appropriate therapy to treat mycoplasma pneumonia? - correct
answer ✔✔tetracyclines:
questions well answered to pass
Pharmacokinetics - correct answer ✔✔The process by which drugs are absorbed,
distributed within the body, metabolized, and excreted.
Pharmacodynamics - correct answer ✔✔The process by which a medication works
on the body.
Pharmacogenomics - correct answer ✔✔The study of how genetic inheritance
affects the body's response to drugs
What is the role of lipid-soluble, hydrophilic drugs, and simple diffusion in getting
medications into cells? - correct answer ✔✔
Explain the concept of drug: potency, efficacy, side-effect, onset of action,
minimum effective concentration, peak level, therapeutic range, duration of
action, therapeutic index, therapeutic effect, mechanism of action, and steady
state. - correct answer ✔✔
Four processes involved when a drug is taken: - correct answer ✔✔1. absorption
2. distribution
3. metabolism
4. elimination/excretion
, Explain the relationship of the Brain-blood barrier in pharmacodynamics of
medications. - correct answer ✔✔Blood vessels (capillaries) selectively let certain
substances enter the brain tissue and keep other substances out. uses only lipid
soluble or transport system
What determines the degree of movement of a drug between body
compartments? - correct answer ✔✔1. degree of hydrophila
2. degree lipophilicity
3. molecular weight
Define and explain the purpose of synergistic antibiotic combination of antibiotics.
Give examples of this practice. - correct answer ✔✔Abx that work in tandem to
increase efficacy.
Ex: amoxicillin + clavulanic acid (Augmentin) or piperacillin + tazobactam (Zosyn)
Explain why Clavulanic acid is added to amoxicillin. - correct answer ✔✔to make it
more effective against bacteria that produce beta lactamase
Explain the risk of prolonged QT syndrome and torsade de pointes and give
examples of medications that may cause this problem. - correct answer
✔✔Macrolides (azithromycin, clarithromycin, erythromycin)
What would be appropriate therapy to treat mycoplasma pneumonia? - correct
answer ✔✔tetracyclines:
