INTRODUCTORYCLINICAL PHARMACOLOGY 12TH EDITION
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bySusan M Ford
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, Chapter01:General PrinciplesofPharmacology yz yz yz yz yz
Ford:IntroductoryClinicalPharmacology12thEdition
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1. Afterteachingagroupofstudentsaboutthebasicsofpharmacology,thestudentswill beable to
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choose which aspect as the most critical toremember?
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A) Drugname yz
B) Drugclass yz
C) Drugaction yz
D) Drugsource yz
Answer: C yz
Rationale: Pharmacology is the study of drugs and its action on living organisms. Thus, an
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essential aspect of pharmacology is drug action. An understanding of the drug name, drug class,
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and drug source is important, but the most critical aspect related to pharmacology is how the drug
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acts in the body.
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QuestionFormat:MultipleChoice yz yz yz
Chapter: 1
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Learning Objective: 1 yz yz
CognitiveLevel:Apply
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ClientNeeds:PhysiologicalIntegrity:PharmacologicalTherapies
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Integrated Process: Teaching/Learning
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Reference: p. 3, Introduction yz yz yz
2. A nurse suspects the client had an adverse reaction to a prescribed medication due to an
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interaction with an unreported over-the-counter supplement. Which action by the nurse will
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best assist in preventing future similarincidents?
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A) File a report withMedWatch yz yz yz yz
B) File a report with the State Board ofNursing
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C) Instruct the client to avoid combining medications in thefuture yz yz yz yz yz yz yz yz yz
D) Document the incident and report it to the health careprovider yz yz yz yz yz yz yz yz yz yz
Answer: A yz
Rationale: Nurses playan important role in monitoring for adverse reactions. Therefore, it is
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important to submit reports, even if there is uncertainty about the cause–effect relationship. The
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FDA protects the identity of those who voluntarily report adverse reactions.
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QuestionFormat:MultipleChoice yz yz yz
Chapter: 1
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Learning Objective: 9 yz yz
CognitiveLevel:Apply
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, Client Needs: Safe and Effective Care Environment: Safetyand InfectionControl
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Integrated Process: Clinical Problem-solvingProcess (NursingProcess)
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Reference: p. 7, Box 1.1 MedWatch and Reporting Adverse Events
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3. A nurse is assessing a client and notes the client has developed swelling of the eyelids and lips
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after administration of a prescribed medication. What does the nurse interpret this finding to
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specificallyindicate?
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A) Mild allergic reaction yz yz
B) Anaphylacticshock yz
C) Angioedema
D) Drugidiosyncrasy yz
Answer: C yz
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of fluid in
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the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and throat. Allergic
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reactions can be manifested by a wide range of signs and symptoms such as itching, rashes, and
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hives. Anaphylactic shock is a serious allergic reaction that requires immediate medical
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attention. Drugidiosyncrasydescribesanyunusualorabnormalreactionto adrug, onethat is
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different from the one normally expected.
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QuestionFormat:MultipleChoice yz yz yz
Chapter: 1
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Learning Objective: 5 yz yz
CognitiveLevel:Apply
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Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated
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Process: Clinical Problem-solvingProcess (NursingProcess) Reference: p. 12,
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Allergic Drug Reactions
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4. The nurse is preparing to teach a client about a new drug which is in the fourth phase of
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development. Which activity will the nurse explain best illustrates this phase?
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A) Health care providers report adverse effects toFDA. yz yz yz yz yz yz yz
B) Healthy volunteers are involved in thetest. yz yz yz yz yz yz
C) In vitro tests are performed using humancells.
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D) The drug is given to clients with thedisease.
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Answer: A yz
, Rationale: The postmarketing surveillance phase of drug development encourages health care yz yz yz yz yz yz yz yz yz yz
professionalstoreportadverseeffects ofdrugstotheFDA usingMedWatch. Phase1ofclinical testing
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involves 20 to 100 healthy volunteers. In vitro testing of the drug on human or animal cellsisdonein
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the pre-FDA phase. In Phase 2 of clinical testing, the drug is given to clients with the disease for which
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the drug is manufactured.
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QuestionFormat:MultipleChoice yz yz yz
Chapter: 1
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Learning Objective: 4 yz yz
CognitiveLevel:Apply
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Client Needs: Health Promotion and Maintenance
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IntegratedProcess:Teaching/LearningReference:p.7,
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Concept Mastery Alert
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5. A nurse is assessing a pregnant client who admits to having a cocaine addiction. Which
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condition of the baby after birth should the nurse explain and preparethe client for?
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A) Diabetes
B) Hypertension
C) Addiction to drugs yz yz
D) CNS defects yz
Answer: C yz
Rationale: The nurse informs the client that children born to mothers using addictive drugs are
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often born with an addiction to the drug. Children born to mothers who are addicted to cocaine
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are not known to be born with diabetes, CNS defects, or hypertension.
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QuestionFormat:MultipleChoice yz yz yz
Chapter: 1
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Learning Objective: 6 yz yz
CognitiveLevel:Apply
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ClientNeeds:HealthPromotionandMaintenance Integrated
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Process: Teaching/Learning
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Reference: p. 11, Drug Use, Pregnancy, and Lactation yz yz yz yz yz yz yz
6. A client arrives at the health care clinic and reports taking several pills for a headacheand
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severe coughwithoutrelief.Whichadverseeffectshouldthenurse be aware maydevelop from
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this combination?
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A) Gastrointestinal bleeding yz
B) Breathingdifficulties yz
C) Liverdamage yz
D) Anaphylaxis