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TEST BANK FOR PORTH'S ESSENTIALS OF PATHOPHYSIOLOGY 5TH EDITION BY TOMMIE L. NORRIS ALL CHAPTERS COVERED

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1. Chapter 34 Which of the following physiologic principles would be considered a function of the somatic nervous system? A) The act of typing a report using a computer keyboard B) Withdrawing the hand after touching a hot surface C) The patellar reflex "knee jerk" activated by tapping the patellar tendon abdominal viscera D) The beginning of depolarization in the cardiac conduction of impulses Ans: A Feedback: The somatic nervous system provides sensory and motor innervation for all parts of the central nervous system (CNS) and peripheral nervous system (PNS) except viscera, smooth muscle, and glands. The autonomic nervous system (ANS) provides efferent motor innervation to smooth muscle, the conducting system of the heart, and glands. 2. Following a car accident that has resulted in partial amputation of the lower limbs, the client's body has implemented a compensatory mechanism releasing antidiuretic hormone (ADH) into the blood stream, causing retention of water and vasoconstriction of blood vessels. This is accomplished as a result of: A) Rapid axonal transport of ADH from the hypothalamus into the posterior pituitary B) Extension of Nissl bodies and free ribosomes carrying ADH into the dendrites C) Feedback: Dendrites conducting information and ADH toward the cell body D) Afferent, or sensory, neurons of the PNS transmitting information to the CNS Ans: A Antidiuretic hormone (ADH) and oxytocin, which are synthesized by neurons in the hypothalamus, are carried by rapid axonal transport to the posterior pituitary, where the hormones are released into the bloodstream. ADH increases peripheral vascular resistance (vasoconstriction) and thus increases arterial blood pressure. This becomes an important compensatory mechanism for restoring blood pressure in hypovolemic shock such as that which occurs during hemorrhage. The proteins and other materials used by the axon are synthesized in the cell body and then flow down the axon through its cytoplasm. The Nissl bodies and free ribosomes extend into the dendrites, but not into the axon. The dendrites (i.e., ―treelike‖) are multiple, branched extensions of the nerve cell body; they conduct information toward the cell body and are the main source of information for the neuron. The dendrites and cell body are studded with synaptic terminals that communicate with axons and dendrites of other neurons. Page 1 3. A 60-year-old woman has been recently diagnosed with multiple sclerosis, a disease in which the oligodendrocytes of the client's central nervous system (CNS) are progressively destroyed. Which physiologic process within the neurologic system is most likely to be affected by this disease process? A) Oxygen metabolism B) Neurotransmitter synthesis C) Nerve conduction D) Production of cerebrospinal fluid Ans: C Feedback: The oligodendrocytes form the myelin in the central nervous system (CNS). As with peripheral myelinated fibers, the covering of axons in the CNS increases the velocity of nerve conduction. Oxygen metabolism and synthesis of CSF and neurotransmitters are not directly affected. 4. Following a stroke, injury to nerve cells within the central nervous system needs to be repaired. The health care provider knows that which of the following processes explains how this occurs? A) Astrocytes fill up the space to form a glial scar, repairing the area and replacing the CNS cells that cannot regenerate. B) C) Ependymal cells are responsible for phagocytosis. D) Oligodendrocytes are responsible for integrative metabolism. Ans: A The microglia are responsible for cleaning up debris after cerebral infection, or cell death. Feedback: Astrocytes are the largest and most numerous of neuroglia and are particularly prominent in the gray matter of the CNS. They form a network within the CNS and communicate with neurons to support and modulate their activities. Astrocytes are also the principal cells responsible for repair and scar formation in the brain. The microglia is a small phagocytic cell that is available for cleaning up debris after cellular infection or cell death. The ependymal cell forms the lining of the neural tube cavity, the ventricular system. The oligodendrocytes form the myelin in the CNS. Instead of forming a myelin covering for a single axon, these cells reach out with several processes, each wrapping around and forming a multilayered myelin segment around

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TEST BANK FOR PORTH'S
ESSENTIALS OF PATHOPHYSIOLOGY
5TH EDITION BY TOMMIE L. NORRIS
ALL CHAPTERS COVERED ISBN-10;
1975107195/ ISBN-13; 978-1975107192/
GRADED A

,Porth's Essentials of Pathophysiology 5th edition
TB_
1. Chapter 1

Although the basic structure of the cell plasma membrane is formed by a lipid bilayer,
most of the specific membrane functions are carried out by:
A) Bound and transmembrane proteins
B) Complex, long carbohydrate chains
C) Surface antigens and hormone receptors
D) A gating system of selective ion channels
Ans: A
Feedback:
The functions of plasma membrane depend on the presence of proteins that are bound in
the lipid bilayer and some that have the ability to pass freely into and out of the cell.
Carbohydrate chains form a cell coat that surrounds the membrane and that contain
surface antigens and surface hormone receptors. Some ion channels are gated and open
only when the membrane potential changes significantly.


2. Which describes the function of the nucleus?
A) It is basically the site of protein synthesis in the body.
B) It contains the genetic code for the individual.
C) It is the transformer of cellular energy.
D) It initiates the process of aerobic metabolism.
Ans: B
Feedback:
The nucleus contains DNA, which contains the genetic code that contains the
information that controls cells. Ribosomes synthesize protein. Mitochondria transform
organic compounds into cellular energy. Mitochondria require oxygen for aerobic
metabolism, using hydrogen and carbon combined with oxygen molecules to form
carbon dioxide and water as energy is released.


3. Which of the following aspects of the function of the nucleus is performed by ribosomal
RNA (rRNA)?
A) Copying and carrying DNA instructions for protein synthesis
B) Carrying amino acids to the site of protein synthesis
C) Providing the site where protein synthesis occurs
D) Regulating and controlling protein synthesis
Ans: C
Feedback:
There are three types of ribonucleic acid (messenger RNA, ribosomal RNA, and transfer
RNA) that move to the cytoplasm and carry out the actual synthesis of proteins.
Messenger RNA (mRNA) copies and carries the DNA instructions for protein synthesis
to the cytoplasm; ribosomal RNA (rRNA) is the site of protein synthesis; and transfer
Page 1

,RNA (tRNA) transports amino acids to the site of protein synthesis for incorporation
into the protein being synthesized.




Page 2

, 4. Which accurately explains the functions of the organelles lysosomes? They:
A) Are sacs filled with enzymes that breakdown and remove foreign substances and
worn-out cell parts
B) Function in association with the endoplasmic reticulum to modify protein end
products and package them into secretory granules or vesicles
C) Are small particles of nucleoproteins that are involved in the synthesis of proteins
that remain in the cell as cytoplasmic structural or functional elements
D) Are a dynamic system of interconnected membranous tubes that functions as a
tubular communication system for transporting various substances from one part
of the cell to another
Ans: A
Feedback:
Lysosomes are sacs that are filled with hydrolytic enzymes that aid in the processing
and removal of unwanted substances within the cytoplasm. The Golgi apparatus
functions in association with the endoplasmic reticulum to modify and package
substances in preparation for secretion, whereas ribosomes are small particles of
nucleoproteins that are involved in the synthesis of proteins. The ER is a tubular
communication system for transporting various substances from one part of the cell to
another.


5. Impairment in the function of peroxisomes would result in:
A) Inadequate sites for protein synthesis
B) An inability to transport cellular products across the cell membrane
C) Insufficient energy production within a cell
D) Accumulation of free radicals in the cytoplasm
Ans: D
Feedback:
Peroxisomes function in the control of free radicals; unless degraded, these highly
unstable chemical compounds damage other cytoplasmic molecules. Peroxisomes do not
directly contribute to energy production, protein synthesis, or transport of cellular
secretions.




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