INTRODUCTORY CLINICAL PHARMACOLOGY 12TH EDITION
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by Susan M Ford
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, Chapter 01: General Principles of Pharmacology wu wu wu wu wu
Ford:Introductory ClinicalPharmacology 12thEdition
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1. Afterteachingagroupofstudentsaboutthebasicsofpharmacology,thestudentswill be able to
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choose which aspect as the most critical toremember?
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A) Drug name wu
B) Drug class wu
C) Drugaction w
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D) Drug source wu
Answer: C wu
Rationale: Pharmacology is the study of drugs and its action on living organisms. Thus, an
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essential aspect of pharmacology is drug action. An understanding of the drug name, drug class,
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and drug source is important, but the most critical aspect related to pharmacology is how the drug
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acts in the body.
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QuestionFormat:MultipleChoice w
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Chapter: 1
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Learning Objective: 1 wu wu
CognitiveLevel:Apply
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Client Needs: Physiological Integrity: Pharmacological Therapies
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Integrated Process: Teaching/Learning
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Reference: p. 3, Introduction wu wu wu
2. A nurse suspects the client had an adverse reaction to a prescribed medication due to an
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interaction with an unreported over-the-counter supplement. Which action by the nurse
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will best assist in preventing future similar incidents?
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A) File a report withMedWatch wu wu wu w
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B) File a report with the State Board ofNursing
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C) Instruct the client to avoid combining medications in thefuture wu wu wu wu wu wu wu wu u
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D) Document the incident and report it to the health careprovider wu wu wu wu wu wu wu wu wu u
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Answer: A wu
Rationale: Nurses play an important role in monitoring for adverse reactions. Therefore, it is
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important to submit reports, even if there is uncertainty about the cause–effect relationship. The
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FDA protects the identity of those who voluntarily report adverse reactions.
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QuestionFormat:MultipleChoice w
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Chapter: 1
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Learning Objective: 9 wu wu
CognitiveLevel:Apply
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, Client Needs: Safe and Effective Care Environment: Safety and InfectionControl
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Integrated Process: Clinical Problem-solving Process (Nursing Process)
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Reference: p. 7, Box 1.1 MedWatch and Reporting Adverse Events
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3. A nurse is assessing a client and notes the client has developed swelling of the eyelids and lips
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after administration of a prescribed medication. What does the nurse interpret this finding to
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specifically indicate?
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A) Mild allergic reaction wu wu
B) Anaphylactic shock wu
C) Angioedema
D) Drug idiosyncrasy wu
Answer: C wu
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of fluid in
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the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and throat. Allergic
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reactions can be manifested by a wide range of signs and symptoms such as itching, rashes, and
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hives. Anaphylactic shock is a serious allergic reaction that requires immediate medical
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attention. Drugidiosyncrasydescribesanyunusualor abnormalreactionto adrug, one that is
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different from the one normally expected.
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QuestionFormat:MultipleChoice w
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Chapter: 1
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Learning Objective: 5 wu wu
CognitiveLevel:Apply
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Client Needs: Physiological Integrity: Reduction of Risk Potential Integrated
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Process: Clinical Problem-solving Process (Nursing Process) Reference: p. 12,
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Allergic Drug Reactions
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4. The nurse is preparing to teach a client about a new drug which is in the fourth phase of
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development. Which activity will the nurse explain best illustrates this phase?
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A) Health care providers report adverse effects to FDA. wu wu wu wu wu wu w
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B) Healthy volunteers are involved in thetest. wu wu wu wu wu u
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C) In vitro tests are performed using humancells.
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D) The drug is given to clients with thedisease.
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Answer: A wu
, Rationale: The postmarketing surveillance phase of drug development encourages health care wu wu w
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professionals to report adverse effects of drugs to the FDA using MedWatch. Phase 1 of clinical
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testing involves 20 to 100 healthy volunteers. In vitro testing of the drug on human or animal cells
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isdoneinthepre-FDAphase. InPhase2ofclinicaltesting,thedrugisgiventoclientswith thedisease for
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which the drug is manufactured.
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QuestionFormat:MultipleChoice w
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Chapter: 1
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Learning Objective: 4 wu wu
CognitiveLevel:Apply
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Client Needs: Health Promotion and Maintenance
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IntegratedProcess: Teaching/LearningReference: p.7,
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Concept Mastery Alert
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5. A nurse is assessing a pregnant client who admits to having a cocaine addiction. Which
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condition of the baby after birth should the nurse explain and preparethe client for?
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A) Diabetes
B) Hypertension
C) Addiction to drugs wu wu
D) CNS defects wu
Answer: C wu
Rationale: The nurse informs the client that children born to mothers using addictive drugs are
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often born with an addiction to the drug. Children born to mothers who are addicted to cocaine
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are not known to be born with diabetes, CNS defects, or hypertension.
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QuestionFormat:MultipleChoice w
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Chapter: 1
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Learning Objective: 6 wu wu
CognitiveLevel:Apply
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Client Needs: Health Promotion and Maintenance
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Integrated Process: Teaching/Learning
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Reference: p. 11, Drug Use, Pregnancy, and Lactation wu wu wu wu wu wu wu
6. A client arrives at the health care clinic and reports taking several pills for a headacheand
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severe cough without relief.Whichadverseeffect should the nurse be aware may develop from
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this combination?
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A) Gastrointestinal bleeding wu
B) Breathingdifficulties u
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C) Liver damage wu
D) Anaphylaxis