NURS 5220 EXAM QUESTIONS WITH WELL DETAILED
ANSWERS FOR A GUARANTEED PASS
What is the primary factor determining the duration of action of benzodiazepines?
- ✅✅The α phase dynamics of distribution-redistribution from the CNS.
What are the CNS depressant effects of benzodiazepines? - ✅✅Anxiolysis,
sedation, sleep, anticonvulsant, amnesia, muscle relaxation, and inhibition of
alcohol withdrawal symptoms.
What effect do high doses of benzodiazepines have on CMR02 & CBF? -
✅✅They reduce CMR02 & CBF.
What effect do benzodiazepines have on the threshold to local anesthetic-induced
seizures? - ✅✅They increase the threshold to local anesthetic-induced seizures.
What is the dose-related effect of benzodiazepines on anterograde amnesia? -
✅✅They cause anterograde amnesia at high doses.
What does midazolam achieve at low doses? - ✅✅Rapid onset, short duration of
action, and half-life
,How long does the effect of midazolam usually last? - ✅✅20-30 minutes
Does midazolam produce reliable retrograde amnesia? - ✅✅No
What is midazolam commonly used for? - ✅✅Preoperative sedation, anxiolysis,
sedation, and amnesia
What are the cardiovascular effects of midazolam? - ✅✅Minimal effects in
commonly used doses, decrease in blood pressure when combined with opioids in
patients with heart disease or the elderly
What are the respiratory effects of midazolam? - ✅✅Dose-dependent respiratory
depression, increased when combined with other CNS depressants, most
respiratory depressing benzodiazepine
How do hypnotic doses of benzodiazepines affect sleep-related breathing
disorders? - ✅✅Worsen by adversely affecting control of upper airway muscles
and decreasing ventilatory response to CO2
, What are the adverse effects of midazolam? - ✅✅Prolonged sedation, impaired
cognition and psychomotor performance, unwanted amnesia, potential for
delirium, increased risk of accidents and falls, dependence and withdrawal effects
What are the withdrawal effects of benzodiazepines? - ✅✅Delirium, anxiety,
panic, seizures, insomnia, muscle spasm
What are the drug interactions of benzodiazepines? - ✅✅Potential for cross-
tolerance to nonbenzodiazepine GABA anesthetic agents, augmentation of CNS
depressant effects of other sedative-hypnotic anesthetics and opioids
What is the most prescribed psychiatric medication in the US? - ✅✅Alprazolam
(Xanax)
What is the primary use of alprazolam? - ✅✅Anxiolysis
What is the half-life of alprazolam? - ✅✅12-15 hours
What is lorazepam (Ativan) utilized for? - ✅✅Anxiety, alcohol withdrawal,
sedation
What is the half-life of lorazepam? - ✅✅10-22 hours
ANSWERS FOR A GUARANTEED PASS
What is the primary factor determining the duration of action of benzodiazepines?
- ✅✅The α phase dynamics of distribution-redistribution from the CNS.
What are the CNS depressant effects of benzodiazepines? - ✅✅Anxiolysis,
sedation, sleep, anticonvulsant, amnesia, muscle relaxation, and inhibition of
alcohol withdrawal symptoms.
What effect do high doses of benzodiazepines have on CMR02 & CBF? -
✅✅They reduce CMR02 & CBF.
What effect do benzodiazepines have on the threshold to local anesthetic-induced
seizures? - ✅✅They increase the threshold to local anesthetic-induced seizures.
What is the dose-related effect of benzodiazepines on anterograde amnesia? -
✅✅They cause anterograde amnesia at high doses.
What does midazolam achieve at low doses? - ✅✅Rapid onset, short duration of
action, and half-life
,How long does the effect of midazolam usually last? - ✅✅20-30 minutes
Does midazolam produce reliable retrograde amnesia? - ✅✅No
What is midazolam commonly used for? - ✅✅Preoperative sedation, anxiolysis,
sedation, and amnesia
What are the cardiovascular effects of midazolam? - ✅✅Minimal effects in
commonly used doses, decrease in blood pressure when combined with opioids in
patients with heart disease or the elderly
What are the respiratory effects of midazolam? - ✅✅Dose-dependent respiratory
depression, increased when combined with other CNS depressants, most
respiratory depressing benzodiazepine
How do hypnotic doses of benzodiazepines affect sleep-related breathing
disorders? - ✅✅Worsen by adversely affecting control of upper airway muscles
and decreasing ventilatory response to CO2
, What are the adverse effects of midazolam? - ✅✅Prolonged sedation, impaired
cognition and psychomotor performance, unwanted amnesia, potential for
delirium, increased risk of accidents and falls, dependence and withdrawal effects
What are the withdrawal effects of benzodiazepines? - ✅✅Delirium, anxiety,
panic, seizures, insomnia, muscle spasm
What are the drug interactions of benzodiazepines? - ✅✅Potential for cross-
tolerance to nonbenzodiazepine GABA anesthetic agents, augmentation of CNS
depressant effects of other sedative-hypnotic anesthetics and opioids
What is the most prescribed psychiatric medication in the US? - ✅✅Alprazolam
(Xanax)
What is the primary use of alprazolam? - ✅✅Anxiolysis
What is the half-life of alprazolam? - ✅✅12-15 hours
What is lorazepam (Ativan) utilized for? - ✅✅Anxiety, alcohol withdrawal,
sedation
What is the half-life of lorazepam? - ✅✅10-22 hours
