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Katzung'sBasicandClinical
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i i Pharmacology, 16th Edition i i i
by ToddW. Vanderah,Chapters1 -66
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Katzung's Basic and Clinical Pharmacology
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TableofContents i i
1. Introduction: The Nature of Drugs & Drug Development & Regulation
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2. Drug Receptors & Pharmacodynamics
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3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action i i i i i i i i i i i
4. Drug Biotransformation
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5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology i i i
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs i i i
8. Cholinoceptor-Blocking Drugs i
9. Adrenoceptor Agonists & Sympathomimetic Drugs i i i i
10. Adrenoceptor Antagonist Drugs i i
11. Antihypertensive Agents i
12. Vasodilators & the Treatment of Angina Pectoris i i i i i i
13. Drugs Used in Heart Failure
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14. Agents Used in Cardiac Arrhythmias
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15. Diuretic Agents i
16. Histamine, Serotonin, & the Ergot Alkaloids
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17. Vasoactive Peptides i
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
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19. Nitric Oxide i
20. Drugs Used in Asthma
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21. Introduction to the Pharmacology of CNS Drugs i i i i i i
22. Sedative-Hypnotic Drugs i
23. The Alcohols
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24. Antiseizure Drugs i
25. General Anesthetics i
26. Local Anesthetics
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27. Skeletal Muscle Relaxants i i
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders i i i i i i i
29. Antipsychotic Agents & Lithium i i i
30. Antidepressant Agents i
31. Opioid Agonists & Antagonists
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32. Drugs of Abuse i i
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
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34. Drugs Used in Disorders of Coagulation
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35. Agents Used in Dyslipidemiai i i
Katzung's Basic and Clinical Pharmacology
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36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs
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Used in Gout
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37. Hypothalamic & Pituitary Hormones i i i
38. Thyroid & Antithyroid Drugs i i i
39. Adrenocorticosteroids & Adrenocortical Antagonists i i i
40. The Gonadal Hormones & Inhibitors
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41. Pancreatic Hormones & Antidiabetic Drugs i i i i
42. Agents That Affect Bone Mineral Homeostasis
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43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics i i i i i i i
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinonesi i i i i i
45. Aminoglycosides & Spectinomycin i i
46. Sulfonamides, Trimethoprim, & Quinolones i i i
47. Antimycobacterial Drugs i
48. Antifungal Agents i
49. Antiviral Agents i
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants i i i i i i
51. Clinical Use of Antimicrobial Agents
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52. Antiprotozoal Drugs i
53. Clinical Pharmacology of the Antihelminthic Drugs
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54. Cancer Chemotherapy i
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental i i i i i
57. Heavy Metal Intoxication & Chelators
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58. Management of the Poisoned Patient i i i i
59. Special Aspects of Perinatal & Pediatric Pharmacology
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60. Special Aspects of Geriatric Pharmacology
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61. Dermatologic Pharmacology i
62. Drugs Used in the Treatment of Gastrointestinal Diseases
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63. Therapeutic & Toxic Potential of Over-the-Counter Agents i i i i i i
64. Dietary Supplements & Herbal Medications
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65. Rational Prescribing & Prescription Writing
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66. Important Drug Interactions & Their Mechanisms
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Katzung's Basic and Clinical Pharmacology
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Chapter 1. Introduction: The Nature ofDrugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a patient who is
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having a computed tomography (CT) scan. The nurse working on
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the oncology unit qiqadministers chemotherapy to patients who have qiq q i q qiq q iq qiq qiq qiq qiq
cancer. At the Public Health Department, a nurse administers a
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measles-mumps-rubella (MMR) vaccine to a 14-month-old child as qiq qiq qiq q i q qiq qiq qiq qiq
a routine immunization. Which branch of
qiq pharmacology best
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describes the actions of all three nurses? qiq qiq qiq qiq qiq q i q
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses q iq qiq qiq qiq qiq qiq qiq qiq qiq qiq q
iareq involved with clinical pharmacology or pharmacotherapeutics,
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which is a branch of pharmacology that deals with the uses of
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drugs to treat, prevent, and diagnose disease. The radiology nurse
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is administering a drug to help
qiq diagnose a disease. The oncology qiq qiq qiq qiq q i q qiq qiq qiq qiq qiq
nurse is administering a drug to help treat a
qiq qiq disease. qiq qiq qiq qiq qiq qiq q i q qiq
Pharmacoeconomics includes any costs involved in drug therapy. qiq q iq qiq qiq qiq qiq q i q
Pharmacodynamics involves how a drug affects the qiq qiq qiq qiq qiq qiq qiq
body and pharmacokinetics is how the body acts on
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the body. qiq
2. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle
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accident victim. The nurse is aware this drug has a high abuse
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potential. Under what category would morphine be classified?
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A) Schedule I qiq
B) Schedule II qiq
Katzung's Basic and Clinical Pharmacology