Endocrine cSystem cSeveral cglands: c- cCORRECT cANS✔✔Pituitary
Thyroid
Parathyroid
Adrenal
Pancreatic cislets
Ovaries
Testes
Endocrine cSystem c- cCORRECT cANS✔✔Effects calmost cevery ccell, corgan c&function c
Closely clinked cwith cthe cnervous c& cimmune csystems
Negative cfeedback cmechanism
Hormones
Pituitary c- cCORRECT cANS✔✔"Master cGland"
Influences cother cendocrine cglands
Anterior c& cposterior clobes
Controlled cby chypothalamus
~Anterior cPituitary c- cCORRECT cANS✔✔Follicle-stimulating chormone c(FSH)
Luteinizing chormone c(LH)
Adrenocorticotropic chormone c(ACTH)
Thyroid-stimulating chormone c(TSH)
*Growth chormone c(GH cor csomatotropin)
Posterior cPituitary c- cCORRECT cANS✔✔*Anti-diuretic cHormone c(ADH)
Oxytocin
Anti-diuretic chormone c(ADH) c- cCORRECT cANS✔✔Produced cby chypothalamus c-- cSecreted cby
Causes ccontraction cof csmooth cmuscle c- cespecially cblood cvessels
Very cimportant cin cmaintaining cwater cbalance!
Increases cBP
Triggered cby cdehydration
Reason cwhy cvery clittle curination cat cnight/while casleep
Anti-diuretic chormone c(ADH) cDysfunctions c- ctoo cmuch/too clittle c- cCORRECT cANS✔✔SIADH
DI
(SIADH) c- cCORRECT cANS✔✔Syndrome cof cInappropriate cAntidiuretic cHormone cSecretion
Syndrome cof cInappropriate cAntidiuretic cHormone cSecretion c(SIADH) c- cCORRECT cANS✔✔Exc
cpituitary
Cannot cexcrete cdilute curine
Fluid coverload c
, (DI) c- cCORRECT cANS✔✔IS cFATAL cIF cLEFT cUNTREATED!!!!
Thyroid chormones c- cCORRECT cANS✔✔Thyroid chormones: cT3, cT4 c, ccalcitonin
Iodine cis ccontained cin cthyroid chormone
Thyroid chormone ccontrols ccellular cmetabolic cactivity
TSH cfrom cthe canterior cpituitary c- cCORRECT cANS✔✔controls cthe crelease cof cthyroid chormone
TRH cfrom cthe chypothalamus c- cCORRECT cANS✔✔controls cthe crelease cof cTSH
T3 cis c- cCORRECT cANS✔✔more cpotent cand cmore crapid-acting cthan cT4
Calcitonin cis c- cCORRECT cANS✔✔secreted cin cresponse cto chigh cplasma ccalcium clevel cand cinc
cbone
Thyroid cDiagnostic cTests c- cCORRECT cANS✔✔TSH
T3 cand cT4
Radioactive ciodine cuptake
Fine-needle cbiopsy
Thyroid cscan
Thyroid cDisorders c- cCORRECT cANS✔✔Cretinism c
Hypothyroidism
Hyperthyroidism
Goiter c
Graves cDisease
Hypothyroidism cCauses: c- cCORRECT cANS✔✔Autoimmune cthyroiditis; cHashimoto's cdisease c(m
cAffects cwomen c5X cmore cfrequently cthan cmen
Hypothyroidism cManifestations: c- cCORRECT cANS✔✔Early csymptoms cmay cbe cnonspecific
Fatigue; chair closs, cdry cskin, cbrittle cnails, cmenstrual cdisturbances, clow ctemperature cand clow cpu
cresponses cand cmental cresponses care cdulled; cslow cspeech; ctongue, chands, cand cfeet cmay cenl
cchanges; ccardiac cand crespiratory ccomplications; ccomplains cof cbeing ccold call cthe ctime; cconstip
Myxedema cmay cprogress cto cstupor, ccoma, cand cdeath
Hypothyroidism cMedical cManagement c- cCORRECT cANS✔✔Synthetic clevothyroxine-replacemen
c- cSynthroid
c- cDosage cbased con cserum cTSH cconcentration
Medication cinteractions
Effects cof chypnotic cand csedative cagents; creduce cdosage
Support cof ccardiac cfunction cand crespiratory cfunction
Prevention cof ccomplications
Hyperthyroidism c- cCORRECT cANS✔✔Excessive coutput cof cthyroid chormone
Graves cdisease c(most ccommon ctype)
Affects cwomen c8X cmore cfrequently c
cthan cmen
Hyperthyroidism cManifestations c- cCORRECT cANS✔✔thyrotoxicosis—nervousness; cpalpitations;
cpoorly; ctremors; cskin cis cflushed, cwarm, csoft, cand cmoist; cexophthalmos, cincreased cappetite can
cdiarrhea, celevated csystolic cBP; cmay cprogress cto ccardiac cdysrhythmias cand cfailure
Hyperthyroidism cMedical cManagement c- cCORRECT cANS✔✔Radioactive c131I ctherapy c