What are the primary mechanisms of early- and late-phase allergic rhinitis?
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, Early-phase mechanisms are allergen-induced mast cell secretion of
histamine, prostaglandins, and leukotrienes; late-phase mechanisms are
eosinophil chemotaxis, caused by chemical mediators produced in the early
reaction
How would you stage a COPD patient with an FEV1/FVC ratio of 65% and an FEV1 of
45%?
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GOLD stage 3 or severe COPD
A 45-year-old woman presents with ocular pruritis. Other symptoms include redness in
her eyes, difficulty with light, and sometimes pain. When going through her history she
reports that she always feels dry and has problems with dry skin. Her eyes feel like
leather, and you notice that she has lost her eyelashes. She denies any vision problems
requiring glasses or contacts. What is the diagnosis?
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Atopic keratoconjunctivitis
What labs are typically associated with hypocomplementemic urticarial vasculitis
(HUVS)?
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, Increased ESR and dsDNA Ab; low C3, C4, CH50; very low C1q; anti-C1q
antibodies are seen in 100% of HUVS cases.
What are the two broad categories of chemical agents that can cause chemical worker's
lung, paint worker's lung, or plastic worker's lung?
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Isocyanates and anhydrides
What percent change in FEV1 on spirometry after bronchodilator administration is
diagnostic for asthma?
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>12%
A 10-year-old boy is brought into your clinic because of redness in his eyes. His medical
history is notable for seasonal allergic rhinitis and asthma. His main complaints include
significant ocular pruritus, sensitivity to light, and feeling like something is stuck in his
eye. On exam his sclera are injected and his R eyelid is lower than his Left. What is the
diagnosis?
Give this one a try later!
Give this one a try later!
, Early-phase mechanisms are allergen-induced mast cell secretion of
histamine, prostaglandins, and leukotrienes; late-phase mechanisms are
eosinophil chemotaxis, caused by chemical mediators produced in the early
reaction
How would you stage a COPD patient with an FEV1/FVC ratio of 65% and an FEV1 of
45%?
Give this one a try later!
GOLD stage 3 or severe COPD
A 45-year-old woman presents with ocular pruritis. Other symptoms include redness in
her eyes, difficulty with light, and sometimes pain. When going through her history she
reports that she always feels dry and has problems with dry skin. Her eyes feel like
leather, and you notice that she has lost her eyelashes. She denies any vision problems
requiring glasses or contacts. What is the diagnosis?
Give this one a try later!
Atopic keratoconjunctivitis
What labs are typically associated with hypocomplementemic urticarial vasculitis
(HUVS)?
Give this one a try later!
, Increased ESR and dsDNA Ab; low C3, C4, CH50; very low C1q; anti-C1q
antibodies are seen in 100% of HUVS cases.
What are the two broad categories of chemical agents that can cause chemical worker's
lung, paint worker's lung, or plastic worker's lung?
Give this one a try later!
Isocyanates and anhydrides
What percent change in FEV1 on spirometry after bronchodilator administration is
diagnostic for asthma?
Give this one a try later!
>12%
A 10-year-old boy is brought into your clinic because of redness in his eyes. His medical
history is notable for seasonal allergic rhinitis and asthma. His main complaints include
significant ocular pruritus, sensitivity to light, and feeling like something is stuck in his
eye. On exam his sclera are injected and his R eyelid is lower than his Left. What is the
diagnosis?
Give this one a try later!
