MT (AAB) Hematology Exam 2025 With
100% Correct Answers
What is hemoglobin composed of? - correct answers ✔✔4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to? - correct answers ✔✔porphyria
What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood
cell? - correct answers ✔✔to keep iron in the ferrous state
Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than
oxygen? - correct answers ✔✔carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state? -
correct answers ✔✔methemoglobin
Which hemoglobin derivative causes irreversible changes in teh red blood cells? - correct
answers ✔✔sulfhemoglobin
Which of the following hemoglobins is NOT normally present in a normal adult - correct answers
✔✔Hb-S
Which embryonic hemoglobin is normally found in newborns - correct answers ✔✔Hb-F
What is the most abundant hemoglobin in a newborn? - correct answers ✔✔Hb-F
,What is the molecular structure of hemoglobin S? - correct answers ✔✔Valine replaces
glutamic acid in the 6th position of the beta chain
Which of the following hemoglobins is insoluble under lowered oxygen tensions? - correct
answers ✔✔Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle cell anemia - correct
answers ✔✔hemoglobin electrophoresis
In the solubility test for hemoglobin S, what is the reagent responsible for the reduction of the
hemoglobin molecule? - correct answers ✔✔sodium dithionite
In hemoglobin C, what replaces glutamic acid? - correct answers ✔✔lysine
Which RBC inclusion is characteristic of hemoglobin C disease? - correct answers ✔✔rod-
shaped crystals
What is hemoglobin F composed o? - correct answers ✔✔2 alpha + 2 gamma chains
Which hemoglobin is resistant to alkali denaturation - correct answers ✔✔Hb-F
What hemoglobin's are differentiated by the Kleihauer-Betke technique - correct answers
✔✔Hd-A1 from Hb-F
What is the order of migration of hemoglobins, from fastest to slowest, on cellulose acetate at
pH 8.4 - correct answers ✔✔A1, F, S,C
Why is citrate agar used when abnormal hemoglobins are identified on cellulose acetate at pH
8.6? - correct answers ✔✔It seperates hemoglobin S from hemoglobin D
, The cyanmethemoglobin method measures all hemoglobin pigments EXCEPT which one? -
correct answers ✔✔sulfhemoglobin
What is the diluent in the cyanmethhemoglobin method for the determination of hemoglobin? -
correct answers ✔✔Drabkin's solution
What is the normal plasma hemoglobin concentration? - correct answers ✔✔2-3 mg/dL
Which plasma protein binds free hemoglobin - correct answers ✔✔haptoglobin
Which one of the following statements concerning hemolytic anemia is false? - correct answers
✔✔The serum haptoglobin is increased
Myoglobin can be separated from hemoglobin by saturating the specimen with which one of
the following reagents? - correct answers ✔✔ammonium sulfate
The hematocrit is also know as which one of the following terms? - correct answers ✔✔packed
RBC volume
The degree of packing of cells during centrifugation depends on all of the following EXCEPT
which one? - correct answers ✔✔bore size of the microhematocrit tube
During examination of a spun hematocrit, in which layer are the WBC's found? - correct answers
✔✔buffy coat
When performing a microhematocrit, where should one read the percentage of packed RBC
column from a microhematocrit reading device? - correct answers ✔✔below the buffy coat
100% Correct Answers
What is hemoglobin composed of? - correct answers ✔✔4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to? - correct answers ✔✔porphyria
What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood
cell? - correct answers ✔✔to keep iron in the ferrous state
Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than
oxygen? - correct answers ✔✔carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state? -
correct answers ✔✔methemoglobin
Which hemoglobin derivative causes irreversible changes in teh red blood cells? - correct
answers ✔✔sulfhemoglobin
Which of the following hemoglobins is NOT normally present in a normal adult - correct answers
✔✔Hb-S
Which embryonic hemoglobin is normally found in newborns - correct answers ✔✔Hb-F
What is the most abundant hemoglobin in a newborn? - correct answers ✔✔Hb-F
,What is the molecular structure of hemoglobin S? - correct answers ✔✔Valine replaces
glutamic acid in the 6th position of the beta chain
Which of the following hemoglobins is insoluble under lowered oxygen tensions? - correct
answers ✔✔Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle cell anemia - correct
answers ✔✔hemoglobin electrophoresis
In the solubility test for hemoglobin S, what is the reagent responsible for the reduction of the
hemoglobin molecule? - correct answers ✔✔sodium dithionite
In hemoglobin C, what replaces glutamic acid? - correct answers ✔✔lysine
Which RBC inclusion is characteristic of hemoglobin C disease? - correct answers ✔✔rod-
shaped crystals
What is hemoglobin F composed o? - correct answers ✔✔2 alpha + 2 gamma chains
Which hemoglobin is resistant to alkali denaturation - correct answers ✔✔Hb-F
What hemoglobin's are differentiated by the Kleihauer-Betke technique - correct answers
✔✔Hd-A1 from Hb-F
What is the order of migration of hemoglobins, from fastest to slowest, on cellulose acetate at
pH 8.4 - correct answers ✔✔A1, F, S,C
Why is citrate agar used when abnormal hemoglobins are identified on cellulose acetate at pH
8.6? - correct answers ✔✔It seperates hemoglobin S from hemoglobin D
, The cyanmethemoglobin method measures all hemoglobin pigments EXCEPT which one? -
correct answers ✔✔sulfhemoglobin
What is the diluent in the cyanmethhemoglobin method for the determination of hemoglobin? -
correct answers ✔✔Drabkin's solution
What is the normal plasma hemoglobin concentration? - correct answers ✔✔2-3 mg/dL
Which plasma protein binds free hemoglobin - correct answers ✔✔haptoglobin
Which one of the following statements concerning hemolytic anemia is false? - correct answers
✔✔The serum haptoglobin is increased
Myoglobin can be separated from hemoglobin by saturating the specimen with which one of
the following reagents? - correct answers ✔✔ammonium sulfate
The hematocrit is also know as which one of the following terms? - correct answers ✔✔packed
RBC volume
The degree of packing of cells during centrifugation depends on all of the following EXCEPT
which one? - correct answers ✔✔bore size of the microhematocrit tube
During examination of a spun hematocrit, in which layer are the WBC's found? - correct answers
✔✔buffy coat
When performing a microhematocrit, where should one read the percentage of packed RBC
column from a microhematocrit reading device? - correct answers ✔✔below the buffy coat
