WITH 100% RATED ANSWERS
Short-acting beta agonists (SABA) o Provide prompt relief of acute airflow obstruction and
accompanying symptoms:
Cough,
Chest tightness,
Shortness of breath, and
Wheezing
Long Acting Beta Agonists (LABA) o Onset of action varies with specific drug used
o Duration of action > or = 12 hours
o Improves symptom scores and lung function; decreases nocturnal asthma, use of short-acting
beta agonist, number of exacerbation
LABA drugs - Fluticasone and salmeterol (Advair Diskus, Advair HFA)
- Budesonide and formoterol (Symbicort)
- Mometasone and formoterol (Dulera)
- Fluticasone and vilanterol (Breo Ellipta)
Inhaled Corticosteroids (ICS) o Inhaled corticosteroids can be dosed at low, medium, or high
doses
o Most benefits of ICS occur at low to medium doses
, o Effects
Anti-inflammatory, decrease hyper-responsiveness, decrease secretions, and restore integrity
Improve function
Early intervention more effective
Restrictive, reduced lung volumes Musculoskeletal disorders
Tumors
Lung resection, ILD
Chronic Obstructive Pulmonary Disease (COPD)
"Blue bloaters" Chronic bronchitis leads to pulmonary hypertension from chronic alveolar
hypoxia and cor pulmonale develops.
Edema, cyanosis
Polycythemia secondary to the increased erythropoietin stimulation of increased RBC's to
compensate for the chronic hypoxemia
"Pink puffers" Emphysema, severe dyspnea because the diffusing capacity is reduced
Relatively normal ABGs because of high minute ventilation
"Barrel chest" from hyperinflation and thin
COPD " Objective " FIndings AP/lateral chest diameter 1:1 (hyperinflation)
Use of accessory muscles and tachypnea