LATEST ADVANCED PHARMACOLOGY FOR
NP EXAM 22024-2025 350+ QUESTIONS
WITH CORRECT/ VERIFIED ANSWERS
GRADED A+/A
Ray has been diagnosed with hypertension and it is determined that an angiotensin-converting enzyme
inhibitor is needed. Prior to prescribing this drug, the nurse practitioner (NP) should assess for:
Decreased renal function
Angiotensin-converting enzyme (ACE) inhibitors are the drug of choice in treating hypertension in
diabetic patients because they:
All of the above:
Improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
A potentially life-threatening adverse response to an ACE inhibitor is angioedema. Which of the
following statements is true about this adverse response?
Swelling of the tongue and hoarseness are the most common symptoms.
ACE inhibitors are useful in a variety of disorders. Which of the following statements is true about both
their usefulness in a particular disorder and the reason for their use?
Both 1 and 2 are true:
1. They are useful to prevent stable angina because they decrease the thickening of vascular walls due
to decreased modified release.
,2. They are useful to prevent heart failure because they reduce remodeling of injured myocardial
tissues.
Despite good blood pressure control, an NP might change a patient's drug from an ACE inhibitor to an
angiotensin II receptor blocker (ARB) because the ARB:
Does not produce a dry, hacking cough
While taking an ARB, patients need to avoid certain over-the-counter drugs without irst consulting the
provider because:
Both 1 and 2:
1. Cimetidine is metabolized by the CYP3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
Laboratory monitoring for patients on ACE inhibitors or ARBs should include:
Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
Jacob has hypertension, for which a calcium channel blocker has been prescribed. This drug helps
control blood pressure because it:
Decreases the amount of calcium inside the cell
Which of the following adverse effects may occur due to a dihydropyridine-type calcium channel
blocker?
Edema of the hands and feet
Patient teaching related to amlodipine includes:
,Avoid grapefruit juice as it affects the metabolism of this drug.
Vera, age 70, has isolated systolic hypertension. Calcium channel blocker dosages for her should be:
Started at about half the usual dosage
Larry has heart failure, which is being treated with digoxin because it exhibits:
Negative inotropism
Furosemide is added to a treatment regimen for heart failure that includes digoxin. Monitoring for this
combination includes:
Serum potassium
Which of the following create a higher risk for digoxin toxicity? Both the cause and the reason for it must
be correct.
Administration to older adults because of reduced renal function
Serum digoxin levels are monitored for potential toxicity. Monitoring should occur:
Because a reference point is needed to adjust dosage
Which of the following is true about procainamide and its dosing schedule?
Rodrigo has been prescribed procainamide after a myocardial infarction. He is monitored for dyspnea,
jugular venous distention, and peripheral edema because they may indicate:
Onset of congestive heart failure
, Amiodarone has been prescribed in a patient with a supraventricular dysrhythmia. Patient teaching
should include all of the following EXCEPT:
Take a hot shower or bath if you feel dizzy.
The NP orders a thyroid panel for a patient on amiodarone. The patient tells the NP that he does not
have thyroid disease and wants to know why the test has been ordered. Which is a correct response?
Amiodarone inhibits an enzyme that is important in making thyroid hormone and can cause
hypothyroidism.
Isosorbide dinitrate is prescribed for a patient with chronic stable angina. This drug is administered
twice daily, but the schedule is 7 a.m. and 2 p.m. because:
Nitrate tolerance can develop.
We have an expert-written solution to this problem!
Art is a 55-year-old smoker who has been diagnosed with angina and placed on nitrates. He complains of
headaches after using his nitrate. An appropriate reply might be:
In teaching about the use of sublingual nitroglycerine, the patient should be instructed:
To place one tablet under the tongue if chest pain occurs and allow it to dissolve
Donald has been diagnosed with hyperlipidemia. Based on his lipid profile, atorvastatin is prescribed.
Rhabdomyolysis is a rare but serious adverse response to this drug. Donald should be told to:
Report muscle weakness or tenderness and dark urine to his provider immediately.
NP EXAM 22024-2025 350+ QUESTIONS
WITH CORRECT/ VERIFIED ANSWERS
GRADED A+/A
Ray has been diagnosed with hypertension and it is determined that an angiotensin-converting enzyme
inhibitor is needed. Prior to prescribing this drug, the nurse practitioner (NP) should assess for:
Decreased renal function
Angiotensin-converting enzyme (ACE) inhibitors are the drug of choice in treating hypertension in
diabetic patients because they:
All of the above:
Improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
A potentially life-threatening adverse response to an ACE inhibitor is angioedema. Which of the
following statements is true about this adverse response?
Swelling of the tongue and hoarseness are the most common symptoms.
ACE inhibitors are useful in a variety of disorders. Which of the following statements is true about both
their usefulness in a particular disorder and the reason for their use?
Both 1 and 2 are true:
1. They are useful to prevent stable angina because they decrease the thickening of vascular walls due
to decreased modified release.
,2. They are useful to prevent heart failure because they reduce remodeling of injured myocardial
tissues.
Despite good blood pressure control, an NP might change a patient's drug from an ACE inhibitor to an
angiotensin II receptor blocker (ARB) because the ARB:
Does not produce a dry, hacking cough
While taking an ARB, patients need to avoid certain over-the-counter drugs without irst consulting the
provider because:
Both 1 and 2:
1. Cimetidine is metabolized by the CYP3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
Laboratory monitoring for patients on ACE inhibitors or ARBs should include:
Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
Jacob has hypertension, for which a calcium channel blocker has been prescribed. This drug helps
control blood pressure because it:
Decreases the amount of calcium inside the cell
Which of the following adverse effects may occur due to a dihydropyridine-type calcium channel
blocker?
Edema of the hands and feet
Patient teaching related to amlodipine includes:
,Avoid grapefruit juice as it affects the metabolism of this drug.
Vera, age 70, has isolated systolic hypertension. Calcium channel blocker dosages for her should be:
Started at about half the usual dosage
Larry has heart failure, which is being treated with digoxin because it exhibits:
Negative inotropism
Furosemide is added to a treatment regimen for heart failure that includes digoxin. Monitoring for this
combination includes:
Serum potassium
Which of the following create a higher risk for digoxin toxicity? Both the cause and the reason for it must
be correct.
Administration to older adults because of reduced renal function
Serum digoxin levels are monitored for potential toxicity. Monitoring should occur:
Because a reference point is needed to adjust dosage
Which of the following is true about procainamide and its dosing schedule?
Rodrigo has been prescribed procainamide after a myocardial infarction. He is monitored for dyspnea,
jugular venous distention, and peripheral edema because they may indicate:
Onset of congestive heart failure
, Amiodarone has been prescribed in a patient with a supraventricular dysrhythmia. Patient teaching
should include all of the following EXCEPT:
Take a hot shower or bath if you feel dizzy.
The NP orders a thyroid panel for a patient on amiodarone. The patient tells the NP that he does not
have thyroid disease and wants to know why the test has been ordered. Which is a correct response?
Amiodarone inhibits an enzyme that is important in making thyroid hormone and can cause
hypothyroidism.
Isosorbide dinitrate is prescribed for a patient with chronic stable angina. This drug is administered
twice daily, but the schedule is 7 a.m. and 2 p.m. because:
Nitrate tolerance can develop.
We have an expert-written solution to this problem!
Art is a 55-year-old smoker who has been diagnosed with angina and placed on nitrates. He complains of
headaches after using his nitrate. An appropriate reply might be:
In teaching about the use of sublingual nitroglycerine, the patient should be instructed:
To place one tablet under the tongue if chest pain occurs and allow it to dissolve
Donald has been diagnosed with hyperlipidemia. Based on his lipid profile, atorvastatin is prescribed.
Rhabdomyolysis is a rare but serious adverse response to this drug. Donald should be told to:
Report muscle weakness or tenderness and dark urine to his provider immediately.
