https://www.stuvia.com/
TEST BANK FOR MODERN BLOOD BANKING &
# # # # # # #
TRANSFUSION PRACTICES 7TH EDITION BY D
# # # # #
ENISE M HARMENING
# #
9780803668881 CHAPTER 1-
# #
29 COMPLETE GUIDE
# #
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
# # # # # # # # # #
Multiple#Choice
Identify#the#choice#that#best#completes#the#statement#or#answers#the#question.
1. Which#metabolic#pathway#is#responsible#for#generating#90%#of#the#ATP#for#the#RBC?
a. Pentose#phosphate#shunt c. Glycolysis
b. Luebering-Rapoport#shunt d.# Methemoglobin#reductase
2. A#unit#of#blood#was#returned#to#the#blood#bank#before#it#was#spiked.#Apparently#the#patient’s#IV#failed.#The#
unit#of#blood#was#outside#the#blood#bank#for#35#minutes.#Which#of#the#statements#below#is#most#accurate?
a. The#unit#of#blood#should#be#discarded#immediately.
b. The#unit#of#blood#can#be#returned#to#inventory.
c. The#unit#of#blood#must#be#transfused#within#4#hours#or#be#discarded#at#the#end#of#that#time.
d. The#unit#of#blood#must#be#transfused#with#24#hours.
3. What#is#the#average#diameter#of#a#platelet?
a. 5#to#10#µm c. 1#to#2#µm
b. 2#to#4#µm d.# # 4#to#6#µm
4. In#the#normal#hemoglobin-
oxygen#dissociation#curve,#what#percentage#of#oxygen#is#released#to#the#tissues#when#PO2# averages#40#m
m#Hg?
a. 75% c. 100%
b. 25% d.# 50%
5. What#factors#are#known#to#influence#platelet#metabolism#and#function?
a. Storage#temperature c. Platelet#count
b. Initial#pH d.# All#of#the#above
6. Which#of#the#following#red#blood#cell#morphologies#may#be#present#on#the#peripheral#blood#smear#as#a#result#
of#loss#of#RBC#membrane?
a. Spherocytes c. Burr#cells
b. Target#cells d.# Schistocytes
7. What#does#the#term#autologous#transfusion#refer#to?
a. A#parent#donating#blood#for#his#or#her#child
b. An#individual#donating#blood#for#a#friend
c. An#individual#donating#blood#for#a#relative
d. An#individual#donating#blood#for#his#or#her#own#transfusion
8. What#is#the#primary#function#of#hemoglobin?
a. Iron#metabolism c. Oxygen#transport
b. Porphyrin#synthesis d.# Signal#transduction
9. All#of#the#following#areas#of#red#blood#cell#biology#are#crucial#for#normal#erythrocyte#survival# except:
a. Cellular#metabolism. c. Site#of#the#ABO#antigen#attachment.
b. RBC#membrane. d.# Hemoglobin#structure.
This#study#source#was#downloaded#by#100000826342158#from#CourseHero.com#on#09-15-2021#17:54:15#GMT#-
05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
# 10.# What#is#the#correct#biochemical#composition#of#the#RBC#membrane?
a. 52%#protein,#40%#lipid,#8%#carbohydrate
b. 40%#protein,#8%#lipid,#52%#carbohydrate
c. 8%#protein,#52%#lipid,#40%#carbohydrate
d. 8%#lipid,#40%#carbohydrate,#52%#protein
# 11.# All#of#the#following#biochemical#changes#are#associated#with#loss#of#red#blood#cell#viability#upon#storage
except:
a. Decreased#pH. c. Increased#ATP#level.
b. Loss#of#red#blood#cell#function. d.# Decreased#glucose#consumption.
# 12.# Which#red#blood#cell#preservative#has#a#storage#time#of#35#days?
a. ACD c. AS-1
b. CPDA-1 d.# # CPD
# 13.# The#RBC#membrane#is#relatively#permeable#to#all#of#the#following#except:
a. Chloride. c. Bicarbonate.
b. Sodium. d.# Water.
# 14.#What#percentage#of#platelets#is#sequestered#in#the#spleen#as#functional#reserve#after#being#released#from#the#
bone#marrow?
a. 30% c. 10%
b. 50% d.# # 25%
# 15.# What#is#the#major#biochemical#consideration#in#platelet#storage?
a. Glucose#metabolism c. Production#of#carbon#dioxide
b. Oxygen#supply d.# Regulation#of#pH
# 16.#What#would#the#hemoglobin-
oxygen#dissociation#curve#depict#in#a#patient#exhibiting#clinical#signs#of#alkalosis?
a. Normal c. Shift#to#the#right
b. Shift#to#the#left d.# None#of#the#above
# 17.# Name#the#main#lipid#components#of#a#red#blood#cell#membrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.# Glycophorin#A
# 18.# The#ABO#blood#groups#were#discovered#in#1901#by#whom?
a. Charles#Drew c. Loutit#and#Mollison
b. Karl#Landsteiner d.# Edward#Lindeman
# 19.#A#standing#order#of#platelets#was#shipped#to#your#facility#by#your#supplier.#It#was#inadvertently#left#in#the#cor
ner#of#the#department#until#discovered#36#hours#later.#What#would#the#appropriate#action#be#for#the#blood#ban
ker?
a. If#the#temperature#in#the#box#was#22#+/-
#2°C#and#the#platelet#swirl#seemed#OK,#it#would#be#OK#to#accept#the#unit#into#inventory.
b. The#platelets#have#fallen#outside#the#supplier’s#quality#assurance.#The#unit#should#be#dis
carded#because#the#pH#has#probably#dropped#too#low#and#platelet#activation#has#been#co
mpromised.
c. If#the#temperature#was#1°C#to#6°C#and#the#platelet#swirl#seemed#OK,#it#would#be#OK#to
This#study#source#was#downloaded#by#100000826342158#from#CourseHero.com#on#09-15-2021#17:54:15#GMT#-
05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
accept#the#unit#into#inventory.
d. If#the#platelets#appeared#OK#and#passed#the#platelet#swirl#test#after#being#placed#on#the#
agitator,#they#could#be#accepted#into#the#inventory.
# 20.# Which#metabolic#pathway#permits#the#accumulation#of#2,3#diphosphoglycerate#(2,3-DPG)?
a. Glycolysis c. Pentose#phosphate#shunt
b. Luebering-Rapoport#shunt d.# Methemoglobin#reductase
# 21.# All#of#the#following#are#consistent#with#a#"shift#to#the#right"#of#the#hemoglobin-oxygen#dissociation#curve
except:
a. Increased#2,3-DPG.
b. 50%#O2# saturation#to#tissues.
c. Decreased#2,3-DPG.
d. Decreased#hemoglobin#affinity#for#O2.
# 22.# What#is#the#normal#platelet#count#range#per#cubic#millimeter?
a. 100#to#350 c. 50,000#to#200,000
b. 150,000#to#350,000 d.# 350,000#to#500,000
# 23.# What#cryoprotective#agent#is#added#to#red#blood#cells#upon#freezing?
a. Dextrose c. Glycerol
b. Adsol d.# All#of#the#above
# 24.# If#platelets#are#to#be#stored#for#5#days#on#a#rotator,#what#is#the#optimal#storage#temperature?
a. 1°C#to#6°C c. 35°C#to#37°C
b. 20°C#to#24°C d.# 1°C#to#10°C
# 25.# What#role#do#platelets#play#in#hemostasis?
a. Maintenance#of#vascular#integrity
b. Initial#arrest#of#bleeding#by#platelet#plug#formation
c. Stabilization#of#the#hemostatic#plug
d. All#of#the#above
# 26.# Which#of#the#following#best#describes#"integral"#membrane#proteins?
a. Reside#at#the#cytoplasmic#surface#of#membrane
b. Span#the#entire#membrane#surface
c. Form#the#red#blood#cell#cytoskeleton
d. None#of#the#above
# 27.# How#is#stroma-free#hemoglobin#solution#prepared?
a. Outdated#red#blood#cells#are#concentrated,#and#stroma#is#removed.
b. Outdated#red#blood#cells#are#diluted#with#saline,#and#stroma#is#removed.
c. Outdated#red#blood#cells#are#lysed,#and#stroma#is#removed.
d. None#of#the#above
# 28.# What#is#the#normal#life#span#of#an#RBC?
a. 100#days c. 120#hours
b. 120#days d.# 2#days
# 29.# Regarding#loss#of#RBC#membrane#deformability,#all#of#the#following#are#true#except:
a. Increase#in#ATP#level.
b. Decrease#in#ATP#level.
This#study#source#was#downloaded#by#100000826342158#from#CourseHero.com#on#09-15-2021#17:54:15#GMT#-
05:00
https://www.coursehero.com/file/25537437/ch01rtf/
TEST BANK FOR MODERN BLOOD BANKING &
# # # # # # #
TRANSFUSION PRACTICES 7TH EDITION BY D
# # # # #
ENISE M HARMENING
# #
9780803668881 CHAPTER 1-
# #
29 COMPLETE GUIDE
# #
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
# # # # # # # # # #
Multiple#Choice
Identify#the#choice#that#best#completes#the#statement#or#answers#the#question.
1. Which#metabolic#pathway#is#responsible#for#generating#90%#of#the#ATP#for#the#RBC?
a. Pentose#phosphate#shunt c. Glycolysis
b. Luebering-Rapoport#shunt d.# Methemoglobin#reductase
2. A#unit#of#blood#was#returned#to#the#blood#bank#before#it#was#spiked.#Apparently#the#patient’s#IV#failed.#The#
unit#of#blood#was#outside#the#blood#bank#for#35#minutes.#Which#of#the#statements#below#is#most#accurate?
a. The#unit#of#blood#should#be#discarded#immediately.
b. The#unit#of#blood#can#be#returned#to#inventory.
c. The#unit#of#blood#must#be#transfused#within#4#hours#or#be#discarded#at#the#end#of#that#time.
d. The#unit#of#blood#must#be#transfused#with#24#hours.
3. What#is#the#average#diameter#of#a#platelet?
a. 5#to#10#µm c. 1#to#2#µm
b. 2#to#4#µm d.# # 4#to#6#µm
4. In#the#normal#hemoglobin-
oxygen#dissociation#curve,#what#percentage#of#oxygen#is#released#to#the#tissues#when#PO2# averages#40#m
m#Hg?
a. 75% c. 100%
b. 25% d.# 50%
5. What#factors#are#known#to#influence#platelet#metabolism#and#function?
a. Storage#temperature c. Platelet#count
b. Initial#pH d.# All#of#the#above
6. Which#of#the#following#red#blood#cell#morphologies#may#be#present#on#the#peripheral#blood#smear#as#a#result#
of#loss#of#RBC#membrane?
a. Spherocytes c. Burr#cells
b. Target#cells d.# Schistocytes
7. What#does#the#term#autologous#transfusion#refer#to?
a. A#parent#donating#blood#for#his#or#her#child
b. An#individual#donating#blood#for#a#friend
c. An#individual#donating#blood#for#a#relative
d. An#individual#donating#blood#for#his#or#her#own#transfusion
8. What#is#the#primary#function#of#hemoglobin?
a. Iron#metabolism c. Oxygen#transport
b. Porphyrin#synthesis d.# Signal#transduction
9. All#of#the#following#areas#of#red#blood#cell#biology#are#crucial#for#normal#erythrocyte#survival# except:
a. Cellular#metabolism. c. Site#of#the#ABO#antigen#attachment.
b. RBC#membrane. d.# Hemoglobin#structure.
This#study#source#was#downloaded#by#100000826342158#from#CourseHero.com#on#09-15-2021#17:54:15#GMT#-
05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
# 10.# What#is#the#correct#biochemical#composition#of#the#RBC#membrane?
a. 52%#protein,#40%#lipid,#8%#carbohydrate
b. 40%#protein,#8%#lipid,#52%#carbohydrate
c. 8%#protein,#52%#lipid,#40%#carbohydrate
d. 8%#lipid,#40%#carbohydrate,#52%#protein
# 11.# All#of#the#following#biochemical#changes#are#associated#with#loss#of#red#blood#cell#viability#upon#storage
except:
a. Decreased#pH. c. Increased#ATP#level.
b. Loss#of#red#blood#cell#function. d.# Decreased#glucose#consumption.
# 12.# Which#red#blood#cell#preservative#has#a#storage#time#of#35#days?
a. ACD c. AS-1
b. CPDA-1 d.# # CPD
# 13.# The#RBC#membrane#is#relatively#permeable#to#all#of#the#following#except:
a. Chloride. c. Bicarbonate.
b. Sodium. d.# Water.
# 14.#What#percentage#of#platelets#is#sequestered#in#the#spleen#as#functional#reserve#after#being#released#from#the#
bone#marrow?
a. 30% c. 10%
b. 50% d.# # 25%
# 15.# What#is#the#major#biochemical#consideration#in#platelet#storage?
a. Glucose#metabolism c. Production#of#carbon#dioxide
b. Oxygen#supply d.# Regulation#of#pH
# 16.#What#would#the#hemoglobin-
oxygen#dissociation#curve#depict#in#a#patient#exhibiting#clinical#signs#of#alkalosis?
a. Normal c. Shift#to#the#right
b. Shift#to#the#left d.# None#of#the#above
# 17.# Name#the#main#lipid#components#of#a#red#blood#cell#membrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.# Glycophorin#A
# 18.# The#ABO#blood#groups#were#discovered#in#1901#by#whom?
a. Charles#Drew c. Loutit#and#Mollison
b. Karl#Landsteiner d.# Edward#Lindeman
# 19.#A#standing#order#of#platelets#was#shipped#to#your#facility#by#your#supplier.#It#was#inadvertently#left#in#the#cor
ner#of#the#department#until#discovered#36#hours#later.#What#would#the#appropriate#action#be#for#the#blood#ban
ker?
a. If#the#temperature#in#the#box#was#22#+/-
#2°C#and#the#platelet#swirl#seemed#OK,#it#would#be#OK#to#accept#the#unit#into#inventory.
b. The#platelets#have#fallen#outside#the#supplier’s#quality#assurance.#The#unit#should#be#dis
carded#because#the#pH#has#probably#dropped#too#low#and#platelet#activation#has#been#co
mpromised.
c. If#the#temperature#was#1°C#to#6°C#and#the#platelet#swirl#seemed#OK,#it#would#be#OK#to
This#study#source#was#downloaded#by#100000826342158#from#CourseHero.com#on#09-15-2021#17:54:15#GMT#-
05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
accept#the#unit#into#inventory.
d. If#the#platelets#appeared#OK#and#passed#the#platelet#swirl#test#after#being#placed#on#the#
agitator,#they#could#be#accepted#into#the#inventory.
# 20.# Which#metabolic#pathway#permits#the#accumulation#of#2,3#diphosphoglycerate#(2,3-DPG)?
a. Glycolysis c. Pentose#phosphate#shunt
b. Luebering-Rapoport#shunt d.# Methemoglobin#reductase
# 21.# All#of#the#following#are#consistent#with#a#"shift#to#the#right"#of#the#hemoglobin-oxygen#dissociation#curve
except:
a. Increased#2,3-DPG.
b. 50%#O2# saturation#to#tissues.
c. Decreased#2,3-DPG.
d. Decreased#hemoglobin#affinity#for#O2.
# 22.# What#is#the#normal#platelet#count#range#per#cubic#millimeter?
a. 100#to#350 c. 50,000#to#200,000
b. 150,000#to#350,000 d.# 350,000#to#500,000
# 23.# What#cryoprotective#agent#is#added#to#red#blood#cells#upon#freezing?
a. Dextrose c. Glycerol
b. Adsol d.# All#of#the#above
# 24.# If#platelets#are#to#be#stored#for#5#days#on#a#rotator,#what#is#the#optimal#storage#temperature?
a. 1°C#to#6°C c. 35°C#to#37°C
b. 20°C#to#24°C d.# 1°C#to#10°C
# 25.# What#role#do#platelets#play#in#hemostasis?
a. Maintenance#of#vascular#integrity
b. Initial#arrest#of#bleeding#by#platelet#plug#formation
c. Stabilization#of#the#hemostatic#plug
d. All#of#the#above
# 26.# Which#of#the#following#best#describes#"integral"#membrane#proteins?
a. Reside#at#the#cytoplasmic#surface#of#membrane
b. Span#the#entire#membrane#surface
c. Form#the#red#blood#cell#cytoskeleton
d. None#of#the#above
# 27.# How#is#stroma-free#hemoglobin#solution#prepared?
a. Outdated#red#blood#cells#are#concentrated,#and#stroma#is#removed.
b. Outdated#red#blood#cells#are#diluted#with#saline,#and#stroma#is#removed.
c. Outdated#red#blood#cells#are#lysed,#and#stroma#is#removed.
d. None#of#the#above
# 28.# What#is#the#normal#life#span#of#an#RBC?
a. 100#days c. 120#hours
b. 120#days d.# 2#days
# 29.# Regarding#loss#of#RBC#membrane#deformability,#all#of#the#following#are#true#except:
a. Increase#in#ATP#level.
b. Decrease#in#ATP#level.
This#study#source#was#downloaded#by#100000826342158#from#CourseHero.com#on#09-15-2021#17:54:15#GMT#-
05:00
https://www.coursehero.com/file/25537437/ch01rtf/
