NURS 617 EXAM 1 / QUESTIONS WITH CORRECT
ANSWERS/ 100% VERIFIED ANSWERS WITH
RATIONALES/ 2025 EDITION!!/GRADED A+
A direct result of anaerobic metabolism during hypoxic cell injury is:
a. increased ATP
b. metabolic acidosis
c. tissue ischemia
d. all of the above. - ANSWER b. metabolic acidosis
Rationale: When oxygen is not available, cells switch to anaerobic metabolism, which yields an
acid called lactate, or lactic acid.
Accumulation of which of the following molecules results in irreversible cell injury?
a. Calcium
b. Melanin
c. Lipids
d. Water - ANSWER a. Calcium
Rationale: The accumulation of calcium causes irreversible mitochondrial injury.
Adaptive cellular mechanisms function to:
a. speed up cellular death.
,b. prevent cellular aging.
c. treat disease.
d. protect cells from injury. - ANSWER d.protect cells from injury.
An individual with damage to the spinal cord may experience atrophy of which of the following
organs?
a. Skeletal muscles
b. Skin
c. Liver
d. Brain - ANSWER a. Skeletal muscles
Rationale: Lack of nerve stimulation to skeletal muscles results in muscle atrophy.
Chronic infection of the cervix by the human papillomavirus results in cervical:
a. hormonal hyperplasia.
b. atrophy.
c. dysplasia.
d. metaplasia. - ANSWER c. dysplasia.
Rationale: (Chronic infection or inflammation is a common cause of cervical dysplasia.)
Ethanol (alcohol) causes cell injury by which of the following mechanisms?
a. Cellular dehydration
b. Intracellular sodium loss
c. Lipid accumulation in hepatocytes
,d. Hypoxic injury - ANSWER c. Lipid accumulation in hepatocytes
Rationale: Ethanol metabolism causes lipid accumulation in hepatocytes that decreases liver
function and may result in liver cirrhosis.
In compensatory hyperplasia, growth factors stimulate cell division in response to:
a. decreased hormonal stimulation.
b. ischemia.
c. tissue loss.
d. puberty. - ANSWER c. tissue loss.
Rationale: In response to tissue loss, surrounding cells are stimulated to replace the lost tissue.
In response to an increased workload, such as that caused by high blood pressure
(hypertension), myocardial cells in the left ventricle will adapt through the process of:
a. hyperplasia.
b. hypertrophy.
c. atrophy.
d. dysplasia. - ANSWER b. hypertrophy.
Rationale: In response to the increased workload of hypertension, myocardial cells will
hypertrophy in order to pump harder.
Injury to the endoplasmic reticulum due to hypoxic injury results in:
, a. sodium accumulation.
b. a decrease in protein synthesis.
c. the release of enzymes.
d. lactic acid production. - ANSWER b. a decrease in protein synthesis.
Rationale: Ribosomes are the primary site for protein synthesis. Hypoxic injury and cellular
swelling result in dilation of the rough endoplasmic reticulum, causing the ribosomes to detach.
Loss of the site for protein synthesis results in decreased protein production.
Lead poisoning affects nervous system function by which of the following mechanisms?
a. Lead blocks oxygen delivery to the brain by binding with hemoglobin.
b. Lead interferes with neurotransmitter release.
c. Lead inhibits fatty acid oxidation in the brainstem.
d. Lead causes nervous tissue necrosis. - ANSWER b. Lead interferes with neurotransmitter
release.
Lysosomal rupture during hypoxic injury leads to:
a. autodigestion of cells.
b. cellular acidosis.
c. sodium influx.
d. cellular adaptation - ANSWER a. autodigestion of cells.
Rationale: Lysosomal enzyme release during hypoxic injury causes autodigestion of cells.
Metaplasia involves the replacement of normal cells by:
ANSWERS/ 100% VERIFIED ANSWERS WITH
RATIONALES/ 2025 EDITION!!/GRADED A+
A direct result of anaerobic metabolism during hypoxic cell injury is:
a. increased ATP
b. metabolic acidosis
c. tissue ischemia
d. all of the above. - ANSWER b. metabolic acidosis
Rationale: When oxygen is not available, cells switch to anaerobic metabolism, which yields an
acid called lactate, or lactic acid.
Accumulation of which of the following molecules results in irreversible cell injury?
a. Calcium
b. Melanin
c. Lipids
d. Water - ANSWER a. Calcium
Rationale: The accumulation of calcium causes irreversible mitochondrial injury.
Adaptive cellular mechanisms function to:
a. speed up cellular death.
,b. prevent cellular aging.
c. treat disease.
d. protect cells from injury. - ANSWER d.protect cells from injury.
An individual with damage to the spinal cord may experience atrophy of which of the following
organs?
a. Skeletal muscles
b. Skin
c. Liver
d. Brain - ANSWER a. Skeletal muscles
Rationale: Lack of nerve stimulation to skeletal muscles results in muscle atrophy.
Chronic infection of the cervix by the human papillomavirus results in cervical:
a. hormonal hyperplasia.
b. atrophy.
c. dysplasia.
d. metaplasia. - ANSWER c. dysplasia.
Rationale: (Chronic infection or inflammation is a common cause of cervical dysplasia.)
Ethanol (alcohol) causes cell injury by which of the following mechanisms?
a. Cellular dehydration
b. Intracellular sodium loss
c. Lipid accumulation in hepatocytes
,d. Hypoxic injury - ANSWER c. Lipid accumulation in hepatocytes
Rationale: Ethanol metabolism causes lipid accumulation in hepatocytes that decreases liver
function and may result in liver cirrhosis.
In compensatory hyperplasia, growth factors stimulate cell division in response to:
a. decreased hormonal stimulation.
b. ischemia.
c. tissue loss.
d. puberty. - ANSWER c. tissue loss.
Rationale: In response to tissue loss, surrounding cells are stimulated to replace the lost tissue.
In response to an increased workload, such as that caused by high blood pressure
(hypertension), myocardial cells in the left ventricle will adapt through the process of:
a. hyperplasia.
b. hypertrophy.
c. atrophy.
d. dysplasia. - ANSWER b. hypertrophy.
Rationale: In response to the increased workload of hypertension, myocardial cells will
hypertrophy in order to pump harder.
Injury to the endoplasmic reticulum due to hypoxic injury results in:
, a. sodium accumulation.
b. a decrease in protein synthesis.
c. the release of enzymes.
d. lactic acid production. - ANSWER b. a decrease in protein synthesis.
Rationale: Ribosomes are the primary site for protein synthesis. Hypoxic injury and cellular
swelling result in dilation of the rough endoplasmic reticulum, causing the ribosomes to detach.
Loss of the site for protein synthesis results in decreased protein production.
Lead poisoning affects nervous system function by which of the following mechanisms?
a. Lead blocks oxygen delivery to the brain by binding with hemoglobin.
b. Lead interferes with neurotransmitter release.
c. Lead inhibits fatty acid oxidation in the brainstem.
d. Lead causes nervous tissue necrosis. - ANSWER b. Lead interferes with neurotransmitter
release.
Lysosomal rupture during hypoxic injury leads to:
a. autodigestion of cells.
b. cellular acidosis.
c. sodium influx.
d. cellular adaptation - ANSWER a. autodigestion of cells.
Rationale: Lysosomal enzyme release during hypoxic injury causes autodigestion of cells.
Metaplasia involves the replacement of normal cells by:
