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Test Bank - Genetics Essentials-Concepts and Connections, 5th
Edition (Pierce, 2022), Chapter 1-18 | All Chapters
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,Table of Contents
Chapter 01 Introduction to Genetics
Chapter 02 Chromosomes and Cellular Reproduction
Chapter 03 Basic Principles of Heredity
Chapter 04 Extensions and Modifications of Basic Principles
Chapter 05 Linkage, Recombination, and Eukaryotic Gene Mapping 98
Chapter 06 Chromosome Variation
Chapter 07 Bacterial and Viral Genetic Systems
Chapter 08 DNA-The Chemical Nature of the Gene
Chapter 09 DNA Replication and Recombination
Chapter 10 From DNA to Proteins-Transcription and RNA Processing
Chapter 11 From DNA to Proteins-Translation
Chapter 12 Control of Gene Expression
Chapter 13 Gene Mutations, Transposable Elements, and DNA Repair
Chapter 14 Molecular Genetic Analysis and Biotechnology
Chapter 15 Genomics and Proteomics
Chapter 16 Cancer Genetics
Chapter 17 Quantitative Genetics
Chapter 18 Population and Evolutionary Genetics
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,Chapter 01 Introduction to Genetics
Question:
Why is albinism so rare in most human populations?
A) Albinism is caused by a dominant gene, which is always expressed.
B) Albinism provides a survival advantage in most environments, making it more common.
C) There is strong natural selection against albinism due to the lack of melanin, leading to health
and social disadvantages.
D) Albinism is a recessive trait that is more common in populations with high levels of genetic
diversity.
Answer: C) There is strong natural selection against albinism due to the lack of melanin, leading
to health and social disadvantages.
Rationale:
In most human populations, albinism is rare because it is caused by a recessive allele that does
not provide a survival advantage. People with albinism lack melanin, which makes their skin
more vulnerable to the harmful effects of sunlight and leads to poor eyesight due to the lack of
melanin in the eyes. Additionally, social factors in many cultures, where albinos may be seen as
abnormal, reduce the likelihood of mating and passing on the genes for albinism. As a result,
these alleles are selected against and maintained at low frequencies. The other options do not
accurately explain why albinism is rare in most populations
Question:
Why is albinism much more common among the Hopis of Black Mesa compared to other human
populations?
A) Albinos are valued in Hopi culture, where they are seen as leaders and are celebrated as a
sign of purity, providing them with extra mating opportunities.
,B) The recessive allele for albinism is dominant in the Hopi population, making it more common.
C) There is no selection pressure against albinism in the Hopi population, so the allele remains at
high frequency due to genetic drift.
D) Albinism is a result of a mutation unique to the Hopi people, and genetic isolation has
increased its frequency.
Answer: A) Albinos are valued in Hopi culture, where they are seen as leaders and are
celebrated as a sign of purity, providing them with extra mating opportunities.
Rationale:
In the Hopi villages of Black Mesa, albinos are viewed as special and are considered symbols of
purity, beauty, and intelligence. They often occupy positions of leadership and are excused from
field labor due to their sensitivity to sunlight. This allows them to remain in the village and have
more opportunities to mate, which increases the frequency of the genes for albinism in this
population. In contrast, in most other populations, there is strong natural selection against
albinism due to health disadvantages. The other options (B, C, D) do not accurately describe the
reason why albinism is more common among the Hopis.
Question:
Which one of the following pairings between the subdiscipline of genetics and the phenomenon
is INCORRECT?
A) Evolution — population genetics
B) Gene regulation — molecular genetics
C) Allelic frequency alteration — population genetics
D) Arrangement of genes on chromosome — transmission genetics
E) Chemical nature of the gene — transmission genetics
Answer: E) Chemical nature of the gene — transmission genetics
Rationale:
The correct pairings are:
• Evolution is studied in population genetics, which focuses on genetic variation and how
populations evolve over time.
• Gene regulation is studied in molecular genetics, which deals with the regulation of gene
expression.
, • Allelic frequency alteration is a key concept in population genetics, as it tracks how
allele frequencies change over generations within populations.
• Arrangement of genes on chromosomes falls under transmission genetics, which
focuses on how genes are inherited from one generation to the next.
However, the chemical nature of the gene is not a focus of transmission genetics. Instead, it is
studied in molecular genetics, which looks at the molecular structure of genes and how they
function at a biochemical level. Transmission genetics primarily deals with the inheritance
patterns and how traits are passed down through generations, not the molecular details of the
gene itself.
Question:
The complete genetic makeup of an organism is referred to as its:
A) Chromosome
B) Alleles
C) Locus
D) Genotype
Answer: D) Genotype
Rationale:
The genotype refers to the complete set of genetic material (genes and alleles) of an organism.
It includes all the inherited information, regardless of whether it is expressed as a phenotype
(observable traits).
• Chromosome refers to a structure within the cell that contains a portion of the
organism’s genetic material but doesn't represent the full genetic makeup.
• Alleles are the different versions of a gene, and while they are part of the genotype, they
don’t represent the complete genetic makeup of an organism.
• Locus refers to the specific location of a gene on a chromosome.
Question:
Which one of the following topics of research belongs to the discipline of transmission genetics?
A) Inheritance pattern of gene alleles
B) Mechanism of DNA replication
C) Gene expression patterns
, D) Evolution
E) Chemical modification of nucleic acids
Answer: A) Inheritance pattern of gene alleles
Rationale:
Transmission genetics focuses on how genes and traits are inherited from one generation to the
next. The inheritance pattern of gene alleles is central to this subdiscipline, as it involves
understanding how alleles (different versions of a gene) are passed down, often following
Mendelian inheritance patterns.
The other options pertain to different areas of genetics:
• Mechanism of DNA replication is studied in molecular genetics, as it deals with the
processes that copy DNA.
• Gene expression patterns are studied in molecular genetics as well, focusing on how
genes are turned on and off.
• Evolution falls under population genetics, which deals with how genetic variation
changes over time in populations.
• Chemical modification of nucleic acids is part of epigenetics, which involves changes in
gene expression or function without altering the underlying DNA sequence.
QUESTION
Tall pea plants (T) are dominant over short pea plants (t). In a Mendelian monohybrid cross, the
F2 generation contains 200 short pea plants. Based on Mendel’s laws, approximately how many
tall plants would be expected in the F2 generation?
Rationales:
• A. 200 – Incorrect. This is the number of short plants, which represents only a portion
of the F2 generation. In a 3:1 Mendelian ratio, short plants are 1 out of 4, so the total
population is larger.
• B. 400 – Incorrect. This would mean a total of 600 plants with 2/3 being tall, which
doesn’t align with the expected 3:1 ratio.