PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN 8th Edition Kathryn L. McCance, Sue E. Huether

PATHOPHYSIOLOGY 8TH EDITION MCCANCE Huether TEST BANK



CHAPTER 01 : CELLULAR BIOLOGY



MULTIPLEMCHOICE



1. WhichMstatementMbestMdescribesMtheMcellularMfunctionMofMmetabolicMabsorption?
a. CellsMcanMproduceMproteins. c. CellsMcanMtakeMinMandMuseMnutrients.
b. CellsMcanMsecreteMdigestiveMenzymes. d.M CellsMcanMsynthesizeMfats.

ANS:M C

InMmetabolicMabsorption,MallMcellsMtakeMinMandMuseMnutrientsMandMotherMsubstances
MfromMtheirMsurroundings.MTheMremainingMoptionsMareMnotMinclusiveMinMtheirMdescri
ptionsMofMcellularMmetabolicMabsorption.



PTS:MMM 1 REF:M PageM2



2. MostMofMaMcell’sMgeneticMinformation,MincludingMRNAMandMDNA,MisMcontainedMinMthe:
a. Mitochondria c. Nucleolus
b. Ribosome d.MMM Lysosome

ANS:M C

TheMnucleusMcontainsMtheMnucleolus,MaMsmallMdenseMstructureMcomposedMlargelyMo
fMRNA,MmostMofMtheMcellularMDNA,MandMtheMDNA-
bindingMproteins,MsuchMasMtheMhistones,MwhichMregulateMitsMactivity.MTheMotherMopt
ionsMdoMnotMcontainMmostMofMaMcell’sMgeneticMinformation.



PTS:MMM 1 REF:M PageM2



3. WhichMcomponentMofMtheMcellMprodNuU
ceRsSIhNyGdTroBg.CenOM
peroxideM(H2O2)MbyMusingMoxy
genMtoMremoveMhydrogenMatomsMfromMspecificMsubstratesMinManMoxidativeMrea
ction?
a. Lysosomes c. Ribosomes
b. Peroxisomes d.M Oxyhydrosomes

ANS:M B


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PeroxisomesMareMsoMnamedMbecauseMtheyMusuallyMcontainMenzymesMthatMuseMoxyge
nMtoMremoveMhydrogenMatomsMfromMspecificMsubstratesMinManMoxidativeMreactionMth
atMproducesMH2O2,MwhichMisMaMpowerfulMoxidantMandMpotentiallyMdestructiveMifMitMa
ccumulatesMorMescapesMfromMperoxisomes.MRibosomesMareMRNA-
proteinMcomplexesM(nucleoproteins)MthatMareMsynthesizedMinMtheMnucleolusMandMsecre
tedMintoMtheMcytoplasmMthroughMporesMinMtheMnuclearMenvelopeMcalledMnuclearMpore
Mcomplexes.MLysosomesMareMsaclikeMstructuresMthatMoriginateMfromMtheMGolgiMcompl
exMandMcontainMmoreMthanM40MdigestiveMenzymesMcalledMhydrolases,MwhichMcatalyz
eMbondsMinMproteins,Mlipids,MnucleicMacids,MandMcarbohydrates.MOxyhydrosomesMareMi
nvolvedMinMenzymeMproduction.



PTS:MMM 1 REF:M PageM8



4. WhichMcellMcomponentMisMcapableMofMcellularMautodigestionMwhenMitMisMreleased
MduringMcellMinjury?
a. Ribosome c. SmoothMendoplasmicMreticulum
b. GolgiMcomplex d.M Lysosomes

ANS:M D




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TheMlysosomalMmembraneMactsMasMaMprotectiveMshieldMbetweenMtheMpowerfulMdiges
tiveMenzymesMwithinMtheMlysosomeMandMtheMcytoplasm,MpreventingMtheirMleakageMi
ntoMtheMcytoplasmicMmatrix.MDisruptionMofMtheMmembraneMbyMvariousMtreatmentsMo
rMcellularMinjuryMleadsMtoMaMreleaseMofMtheMlysosomalMenzymes,MwhichMcanMthenMr
eactMwithMtheirMspecificMsubstrates,McausingMcellularMself-
digestion.MTheMotherMoptionsMdoMnotMcorrectlyMdescribeMthisMprocess.



PTS:MMM 1 REF:M PagesM7-8



5. WhatMisMtheMsequenceMofMstepsMinMtheMdevelopmentMofMaMdigestiveMenzymeMby
MtheMpancreasMcellsMfromMtheMinitialMtranscriptionMtoMtheMreleaseMfromMtheMcell?
a. TheMenzymeMisMtranscribedMfromMDNAMbyMRNAMinMtheMnucleus,Mprocee
dsMtoMtheMribosomeMforMsynthesis,MandMisMtransportedMinMaMsecretoryM
vesicleMtoMtheMcellMmembrane.
b. TheMenzymeMisMtranscribedMfromMRNAMbyMDNAMinMtheMnucleus,MproceedsMt
oMtheMlysosomeMforMsynthesis,MandMisMtransportedMinManMencapsulatedMme
mbraneMtoMtheMcellMmembrane.
c. TheMenzymeMisMtranscribedMbyMtheMmitochondriaMinMtheMnucleus,Mproceed
sMtoMtheMribosomeMforMsynthesis,MandMisMtransportedMinMaMcytoskeletonMt
oMtheMcellMmembrane.
d. TheMenzymeMisMtranscribedMfromMDNAMbyMRNAMinMtheMnucleus,MproceedsM
toMtheMGolgiMcomplexMforMsynthesis,MandMisMtransportedMinMaMcytosolMtoMt
heMcellMmembrane.
ANS:M A

TheMenzymeMisMtranscribedMfromMDNAMbyMRNAMinMtheMnucleus,MproceedsMtoMth
eMribosomeMforMsynthesis,MandMisMtransportedMinMaMsecretoryMvesicleMtoMtheMcellM
membrane.MTheMotherMoptionsMdoMnotMcorrectlyMdescribeMthisMprocess.
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PTS:MMM 1 REF:M PageM7M|MFigureM1-5



6. DuringMwhichMphaseMofMtheMcellMcycleMisMDNAMsynthesized?
a. G1 c. G2
b. S d.M M

ANS:M B

TheMfourMdesignatedMphasesMofMtheMcellMcycleMare:M(1)MtheMG1MphaseM(GM=Mgap),M
whichMisMtheMperiodMbetweenMtheMMMphaseM(MM=Mmitosis)MandMtheMstartMofMDNA

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Msynthesis;M(2)MtheMSMphaseM(SM=Msynthesis),MduringMwhichMDNAMisMsynthesizedMin
MtheMcellMnucleus;M(3)MtheMG2Mphase,MduringMwhichMRNAMandMproteinMsynthesisMoc

curs,MtheMperiodMbetweenMtheMcompletionMofMDNAMsynthesisMandMtheMnextMphaseM(
M);MandM(4)MtheMMMphase,MwhichMincludesMnuclearMandMcytoplasmicMdivision.



PTS:MMM 1 REF:M PageM37



7. WhatMorganicMcompoundMfacilitatesMtransportationMacrossMcellMmembranesMby
MactingMasMreceptors,MtransportMchannelsMforMelectrolytes,MandMenzymesMtoMdri
veMactiveMpumps?
a. Lipids c. Proteins
b. Proteases d.M Carbohydrates

ANS:M C




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