TOP OCN 2025 UPDATE OCN EXAM WITH Q&A 100% CORRECT ANSWERS {CLEANEST VERSION}

TOP OCN 2025 UPDATE OCN EXAM WITH Q&A 100% CORRECT ANSWERS {CLEANEST VERSION} " B Symptoms": Associated w lymphoma diagnoses - CORRECT ANSWER-Fever Night-sweats Weight loss Prurirtus Carry a poorer prognosis Tyrosine Kinase Inhibitors - CORRECT ANSWER-antineoplastic agents- interfere w cell communication and growth by inhibiting the tyrosine kinase enzymeex: Sunitinib ( used in gastric stroma tumors & renal cell ca) Common CA w/ Brain metastases - CORRECT ANSWER-Melanoma Breast Lung Renal Colon Neoplastic Cardiac Tamponade - CORRECT ANSWER-Fluid collection around the heartmost common in breast ca, leukemia, and lymphoma ONC EMERGENCY Neoplastic Cardiac tamponade s/s - CORRECT ANSWER-Tachycardia Decreased SBP Increased CVP Vasoconstriction Pulsus paradoxus JVD Beck's triad for cardiac tamponade. - CORRECT ANSWER-(1) HYPOTENSION (2) MUFFLED or DISTANT HEART SOUNDS (3) JUGULAR VENOUS DISTENSION (JVD) w/ Increased CVP Tx: PERICARDIOCENTESIS TX of choice in bladder CA that has invaded surrounding muscle - CORRECT ANSWER-Radical Cystectomy renal cell carcinoma s/s - CORRECT ANSWER-HTN Cushings Non-metastatic Hepatopathy Hypercalcemia Erythrocytosis Pyrexia Galactorrhea Gynecomastia Serum glucose abnormalities Plummer-Vinson syndrome - CORRECT ANSWER-(ass. with gastric CA) weakness and difficulty swallowing d/t small growths of tissue in esophagus Renal Cell Metastases sites - CORRECT ANSWER-Bone Soft tissue Liver Lung Most commonly diagnosed CA in US - CORRECT ANSWER-Prostate CA (increased prevalence in AA men) radical prostatectomy - CORRECT ANSWER-Not indicated in advanced disease Advanced prostate cancer treatment - CORRECT ANSWER-Chemotherapy, Clinical trials, external beam radiation, hormonal therapy Stage T2 - Prostate Cancer - CORRECT ANSWER-clinically palpable tumor confined to prostate Cabazitaxel (Jevtana) - CORRECT ANSWER-Indicated in hormone refectory metastatic prostate ca Leuprolide acetate (Lupron) - CORRECT ANSWER-Gonadotropin relating hormone used in palliative tx of advanced prostate ca Cryptochidism - CORRECT ANSWER-undescended testes; the condition in which the testes do not descend to the scrotum as they should during prenatal development x5 increase for testicular ca s/s of testicular cancer - CORRECT ANSWER-scrotal "fullness or heaviness," may NOT experience pain, dull ache in lower abdomen, groin, or back, lump in testicle, gynocomastia tumor lysis syndrome - CORRECT ANSWER-Increased risk in hematological CA w/ Increased LDH & increased tumor burden It is characterized by hyperphosphatemia, hypocalcemia, hyperkalemia (EKG changes), and hyperuricemia. Prevention of tumor lysisi syndrome invovles hydration and the use of hypouricemic agents such as allopurinol or rasburicase Disseminated Intravascular Coagulation (DIC) - CORRECT ANSWER-a bleeding disorder that disrupts the bodies ability to clot, resulting in acceleration of clotting cascade and subsequent thrombosis. In DIC increased thrombin results in multiple fibrin clots in circulation that traps platelets- disrupting normal coagulation and decreasing plt count EGFR - CORRECT ANSWER-epidermal growth factor receptor Increase in EGFR associated with more aggressive tumors, poorer prognosis, recurrence, and resistance to endocrine treatment Lapatinib (Tykerb) - CORRECT ANSWER-Tyrosine kinase inhibitor EGFR inhibitor used in treatment of breast CA conjugated monoclonal antibodies - CORRECT ANSWER-- joined to drugs, toxins, or radioactive atoms (cannot be joined to hormones) - used as delivery vehicles to take those substances directly to cancer cells ex. Iodine-131 tositumomab ( Bexxar)- Follicular NHL (not w/ Rituxan) ibritumomab tiuxetan (Zevalin)- NHL ( in combo w/ Rituxan) gemtuzumab ozogamicin (mylotarg)- cd33+ AML unconjugated monoclonal antibodies ex. - CORRECT ANSWER-transtuzumab (Herceptin)- Her2+ Breast CA alemtuzumab ( Lemtrada) - CD52 B cell CLL Estrogen receptor + tumors - CORRECT ANSWER-well differentiated, less likely to respond to single agent chemotherapy - more likely to respond to endocrine therapy - prolonged survival compared to ER - Leading cause of cancer death in women - CORRECT ANSWER-1. Lung CA 2. Breast Ca 3. Colorectal Ca Anxiety causes in advanced disease - CORRECT ANSWER-Disease stage Hormone recreating tumors Hypoxia poorly controlled pain physiological changes Tx regimens Finaical Concerns Family issues Finances Anxiety tx - CORRECT ANSWER-relaxation techniques should be taught when anxiety level is low, pharmacological intervention preferred in moderate- severe anxiety Bone mets - CORRECT ANSWER-Approx 85% of pts w/ bone mets have breast or prostate CA ( also common w lung CA) Biphosphonates - CORRECT ANSWER-Can treat both osteoblastic and osteolytic Used as a preventative measure in its with bone metastases Effective in relieving bone pain