BIOD331 Pathophysiology (Mod 2) Final Test Review 2025 ( With Solns)

BIOD331 Pathophysiology (Module 2)

Final Test Review (Qns & Ans)

2025



1. What is the term for the development of new blood vessels that
support tumor growth?
A. Apoptosis
B. Angiogenesis
C. Dysplasia
D. Anaplasia
ANS: B. Angiogenesis
Rationale: Angiogenesis supplies oxygen and nutrients to the
growing tumor by forming new blood vessels.


2. Which gene functions to suppress tumors by regulating cell
cycle checkpoints?
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, A. BRCA1
B. RAS
C. TP53
D. HER2
ANS: C. TP53
Rationale: TP53, known as the "guardian of the genome," is a
tumor suppressor gene that prevents abnormal cell proliferation.


3. What characteristic distinguishes a malignant tumor from a
benign tumor?
A. Encapsulation
B. Ability to metastasize
C. Slow growth rate
D. Differentiation
ANS: B. Ability to metastasize
Rationale: Malignant tumors invade surrounding tissues and
metastasize, whereas benign tumors remain localized.


4. What is the medical term for cancer of glandular epithelial
tissue?
A. Carcinoma
B. Sarcoma
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, C. Adenocarcinoma
D. Melanoma
ANS: C. Adenocarcinoma
Rationale: "Adeno-" refers to glandular structures, and
"carcinoma" pertains to cancer of epithelial origin.


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True/False Questions
5. Oncogenes are mutated forms of normal proto-oncogenes that
promote uncontrolled cell growth.
ANS: True
Rationale: Oncogenes are derived from proto-oncogenes and
drive unregulated proliferation when activated.


6. Dysplasia is a reversible cellular change that always progresses
to cancer.
ANS: False
Rationale: While dysplasia can progress to cancer, it is not
inevitable and may regress if the stimulus is removed.




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