Know the route of administration for newer agent asenapine (Saphris) and what instructions
should be given to the patient regarding administration. - ANSWER Sublingual
Know and describe the top atypical antipsychotic with greatest incidence of prolonged QTc
interval. - ANSWER Ziprasidone (Geodon).
Know which antipsychotics have specific instructions for minimum food intake or diet
restrictions. - ANSWER Lurasidone (Latuda)
Know an alternative atypical antipsychotic for a patient who has developed diabetes and has a
significant weight gain from treatment with olanzapine. - ANSWER Aripiprazole (Abilify)
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's
granulocyte count is less than 500mm3. What is the most appropriate recommendation for drug
therapy? - ANSWER Discontinue and do not re-start
Know the common effects of smoking along with antipsychotic drug therapy such as olanzapine.
- ANSWER Decreases the plasma levels of Olanzapine (Zyprexa) because of its metabolism at
CYP450 enzyme.
Know what a painful muscle spasm with neck muscles pulling a patient's head to the side called
and Name a common drug therapy to relieve this symptom. - ANSWER Dystonia
Know the role of buspirone in the treatment of anxiety and the recommended dose and time
for onset of action. - ANSWER Takes 3 to 4 weeks for full effect
should be given to the patient regarding administration. - ANSWER Sublingual
Know and describe the top atypical antipsychotic with greatest incidence of prolonged QTc
interval. - ANSWER Ziprasidone (Geodon).
Know which antipsychotics have specific instructions for minimum food intake or diet
restrictions. - ANSWER Lurasidone (Latuda)
Know an alternative atypical antipsychotic for a patient who has developed diabetes and has a
significant weight gain from treatment with olanzapine. - ANSWER Aripiprazole (Abilify)
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's
granulocyte count is less than 500mm3. What is the most appropriate recommendation for drug
therapy? - ANSWER Discontinue and do not re-start
Know the common effects of smoking along with antipsychotic drug therapy such as olanzapine.
- ANSWER Decreases the plasma levels of Olanzapine (Zyprexa) because of its metabolism at
CYP450 enzyme.
Know what a painful muscle spasm with neck muscles pulling a patient's head to the side called
and Name a common drug therapy to relieve this symptom. - ANSWER Dystonia
Know the role of buspirone in the treatment of anxiety and the recommended dose and time
for onset of action. - ANSWER Takes 3 to 4 weeks for full effect
