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Therapeutic outcome raloxifene (Evista) - (answers)decreases bone reabsorption; slows down
bone loss and preserves mineral density in postmenopausal osteoporosis
Also used to protect again breast cancer
Penicillin adverse effects: - (answers)Allergies/anaphylaxis , renal impairment
Macrolide Prototype Drug - (answers)erythromycin (e-mycin)
Airflow Disorders: Teaching About Theophylline - (answers)If dysrhythmias or seizure occur,
stop medication.
Periodic blood levels are needed.
Report nausea, diarrhea, or restlessness.
Avoid consuming caffeinated beverages.
digoxin toxicity symptoms - (answers)fatigue, weakness, vision changes, GI effects
digoxin level - (answers)0.5 to 2.0 ng/mL
How to give digoxin - (answers)infuse over at least 5 min, and monitor client for dysrhythmias.
Management of digoxin toxicity - (answers)Digoxin and potassium-sparing medication should be
stopped immediately.
Monitor K+ levels. For levels less than 3.5 mEq/L, administer potassium IV or by mouth. Do not
,give any further K+ if the level is greater than 5.0 mEq/L.
Treat dysrhythmias with phenytoin (Dilantin) or lidocaine.
Treat bradycardia with atropine.
For excessive overdose, activated charcoal, cholestyramine, or Digibind can be used to bind
digoxin and prevent absorption
How to Treat dysrhythmias for digoxin toxicity patients - (answers)Phenytoin
Lidocaine
Cyclophosphamide Alkylating agent (nitrogen mustard)
Adverse effects: - (answers)Bone marrow suppression
Gi discomfort (N/V)
Acute hemorrhagic cystitis > monitor for hematuria, mesna can be given
Alopecia
Cyclophosphamide interactions - (answers)Succinylcholine > increased neuromuscular blockade
Tricyclic Antidepressants Adverse Reactions - (answers)-Orthostatic hypotension
-Anticholinergic effects
-Sedation
-Toxicity
, -Decrease seizure threshold
-Excessive sweating
controlled substances - (answers)Each level has a decreasing risk of abuse & dependence. For
example, morphine (Duramorph) is a schedule II medication that has greater risk of abuse &
dependence than phenobarbital (Luminal), which is a Schedule IV medication
-Us Food & Drug Administration Pregnancy Risk Category (A, B, C, D, X) classifies medication
in terms of their potential harm during pregnancy, with Category A being safest & Category X
the most dangerous. Teratogenesis is most likely to occur during 1st trimester. Before giving any
medication to a woman who is pregnant or could be pregnant, determine whether or not it is safe
for administration during pregnancy
Tricyclic Antidepressants (TCAs) - (answers)Imipramine (Tofranil)
Doxepin (Sinequan)
Nortriptyline (Aventyl)
Amoxapine (Asendin)
Trimipramine (Surmontil)
Anticholinergic effects Sx - (answers)Dry mouth, blurred vision, photophobia, urinary hesitancy
or retention, constipation, tachycardia
Anticholinergic effects Interventions: - (answers)-Chew sugarless gum, sip water, wear
sunglasses, eat high fiber foods, regular exercise, drink 2-3 L a day, void just before taking
medication
What medications should be avoided while taking TCAs? - (answers)MAOIs, St. John's wort
What interaction do TCAs and antihistamines have? - (answers)Additive anticholinergic effects