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Ileocecal Sphincter The area where food passes from the small intestine into the large
intestine
Distention of the terminal ileum causes relaxation to allow contents to enter the large intestine
Large Intestine Includes the appendix, ascending colon, transverse colon, descending
colon, sigmoid colon and rectum
The mucosa of the large intestine does not have villi and does not produce digestive enzymes:
True
*Contains only absorptive cells to absorb water and electrolytes, goblet cells from mucous and
non-hormonal producing endocrine cells
,Motility of the GI tract is due to contraction of 2 layers of smooth muscle: Longitudinal
and circular
Two Types of GI Motility Propulsive (peristalsis)
Mixing (segmental)
*GI motility is regulated by the enteric nervous system, autonomic nervous system and
hormones
Turnover of large intestine cells: 3-8 days
Turnover of small intestine cells: 48-72 hours
Dysphagia Difficulty swallowing
Causes: mechanical obstruction (stenosis or stricture), tumor or diverticula
, Risk: stroke, bulimia, aspiration, achalasia (LES cannot open properly)
Gastroesphageal Reflux Disease Caused by back flow from the stomach into the
esophagus
Occurs via the lower esophageal spinchter (red and painful)
GERD Complications Inflammation
Pain - burning
Ulceration
Scarring
Strictures
Barrett's esophagus - at risk for cancer
GERD Etiology Fatty foods
Caffeine