TEST BANK
LILLEY'S PHARMACOLOGY FOR CANADIAN HEALTH CARE PRACTICE
KARA SEALOCK
4th Edition
TEST BANK
, lOMoAR cPSD| 3013804
lOMoAR cPSD| 3013804
Chapter 01: Nursing Practice in Canada and Drug Therapy
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
MULTIPLE CHOICE
1. Which is a judgement about a particular patient’s potential need or problem?
a. A goal
b. An assessment
c. Subjective data
d. A nursing diagnosis
ANS: D
Nursing diagnosis is the phase of the nursing process during which a clinical judgement is made about
heath conditions and life processes or vulnerability for that response.
DIF: Cognitive Level: Knowledge
2. The patient is to receive oral furosemide (Lasix) every day; however, because the patient is unable to sw
medication orally, as ordered. The nurse needs to contact the physician. What type of problem is this?
a. A “right time” problem
b. A “right dose” problem
c. A “right route” problem
d. A “right medication” problem
ANS: C
This is a “right route” problem: the nurse cannot assume the route and must clarify the route with the p
time” problem because the ordered frequency has not changed. This is not a “right dose” problem beca
an inability to swallow. This is not a “right medication” problem because the medication ordered will n
DIF: Cognitive Level: Application
3. The nurse has been monitoring the patient’s progress on his new drug regimen since the first dose and h
of possible adverse effects. What nursing process phase is the nurse practising?
a. Planning
b. Evaluation
c. Implementation
d. Nursing diagnosis
ANS: B
Monitoring the patient’s progress is part of the evaluation phase. Planning, implementation, and nursing
illustrated by this example.
DIF: Cognitive Level: Application
4. The nurse is caring for a patient who has been newly diagnosed with type 1 diabetes mellitus. Which st
outcome criterion for this patient?
a. The patient will follow instructions.
b. The patient will not experience complications.
c. The patient adheres to the new insulin treatment regimen.
d. The patient demonstrates safe insulin self-administration technique.
ANS: D
Having the patient demonstrate safe insulin self-administration technique is a specific and measurable o
instructions and avoiding complications are not specific criteria. Adherence to the new insulin treatmen
and would be difficult to measure.
DIF: Cognitive Level: Application
, lOMoAR cPSD| 3013804
6. The nurse is working during a very busy night shift, and the health care provider has just given the nurs
the telephone, but the nurse does not recall the route. What is the best way for the nurse to avoid medic
a. Recopy the order neatly on the order sheet, with the most common route indicated
b. Consult with the pharmacist for clarification about the most common route
c. Call the health care provider to clarify the route of administration
d. Withhold the drug until the health care provider visits the patient
ANS: C
If a medication order does not include the route, the nurse must ask the health care provider to clarify it
administration.
DIF: Cognitive Level: Application | Cognitive Level: Analysis
7. Which constitutes the traditional Five Rights of medication administration?
a. Right drug, right route, right dose, right time, and right patient
b. Right drug, the right effect, the right route, the right time, and the right patient
c. Right patient, right strength, right diagnosis, right drug, and right route
d. Right patient, right diagnosis, right drug, right route, and right time
ANS: A
The traditional Five Rights of medication administration were considered to be Right drug, Right route
Right patient. Right effect, right strength, and right diagnosis are not part of the traditional Five Rights.
DIF: Cognitive Level: Comprehension
8. What correctly describes the nursing process?
a. Diagnosing, planning, assessing, implementing, and finally evaluating
b. Assessing, then diagnosing, implementing, and ending with evaluating
c. A linear direction that begins with assessing and continues through diagnosing,
planning, and finally implementing
d. An ongoing process that begins with assessing and continues with diagnosing,
planning, implementing, and evaluating
ANS: D
The nursing process is an ongoing, flexible, adaptable, and adjustable five-step process that begins with
through diagnosing, planning, implementing, and finally evaluating, which may then lead back to any o
DIF: Cognitive Level: Application
9. When the nurse is considering the timing of a drug dose, which is most important to assess?
a. The patient’s identification
b. The patient’s weight
c. The patient’s last meal
d. Any drug or food allergies
ANS: C
The pharmacokinetic and pharmacodynamic properties of the drug need to be assessed with regard to a
compatibility issues. The patient’s identification, weight, and drug or food allergies are not affected by
DIF: Cognitive Level: Application
10. The nurse is writing nursing diagnoses for a plan of care. Which reflects the correct format for her nurs
a. Anxiety
b. Anxiety related to new drug therapy
c. Anxiety related to anxious feelings about drug therapy, as evidenced by
statements such as “I’m upset about having to give myself shots”
d. Anxiety related to new drug therapy, as evidenced by statements such as “I’m
upset about having to give myself shots”
ANS: D
Formulation of nursing diagnoses is usually a three-step process. The only complete answer is “Anxiet
, lOMoAR cPSD| 3013804
Chapter 02: Pharmacological Principles
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
MULTIPLE CHOICE
1. A patient is receiving two different drugs, which, at their current dose forms and dosages, are both abso
identical amounts. Which term best denotes that the drugs have the same absorption rates?
a. Equivalent
b. Synergistic
c. Compatible
d. Bioequivalent
ANS: D
Two drugs absorbed into the circulation at the same amount (in specific dosage forms) have the same b
bioequivalent. “Equivalent” is incorrect because the term “bioavailability” is used to express the extent
“Synergistic” is incorrect because this term refers to two drugs given together whose resulting effect is
effects of each drug given alone. “Compatible” is incorrect because this term is a general term used to
do not have a chemical reaction when mixed (or given, in the case of drugs) together.
DIF: Cognitive Level: Comprehension
2. A patient is receiving medication via intravenous injection. Which information should the nurse provid
a. The medication will cause fewer adverse effects when given intravenously.
b. The medication will be absorbed slowly into the tissues over time.
c. The medication’s action will begin faster when given intravenously.
d. Most of the drug is inactivated by the liver before it reaches the target area.
ANS: C
Intravenous injections are the fastest route of absorption. The intravenous route does not affect the num
intravenous route is not a slow route of absorption, and the intravenous route does not cause inactivatio
before it reaches the target area.
DIF: Cognitive Level: Comprehension
3. Which is true regarding parenteral drugs?
a. They bypass the first-pass effect.
b. They decrease blood flow to the stomach.
c. They are altered by the presence of food in the stomach.
d. They exert their effects while circulating in the bloodstream.
ANS: A
Drugs given by the parenteral route bypass the first-pass effect, but they still must be absorbed into cell
exert their effects. Enteral drugs (drugs taken orally), not parenteral drugs, decrease blood flow to the s
the presence of food in the stomach. Parenteral drugs must be absorbed into cells and tissues from the c
exert their effects; they do not exert their effects while circulating in the bloodstream.
DIF: Cognitive Level: Analysis
4. A drug’s half-life is best defined as
a. The time it takes for the drug to elicit half its therapeutic response.
b. The time it takes one-half of the original amount of a drug to reach the target
cells.
c. The time it takes one-half of the original amount of a drug to be removed from the
body.
d. The time it takes one-half of the original amount of a drug to be absorbed into the
circulation.
ANS: C
A drug’s half-life is the time it takes for one-half of the original amount of a drug to be removed from t
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6. A fdrug finteracts fwith fenzymes fby
a. altering fcell fmembrane fpermeability.
b. “fooling” fa freceptor fon fthe fcell fwall.
c. enhancing fthe fdrug’s feffectiveness fwithin fthe fcells.
d. “fooling” fthe fenzyme finto fbinding fwith fit finstead fof fits fnormal ftarget fcell.
ANS: fD
When fdrugs finteract fwith fenzymes, fthey finhibit fthe faction fof fa fspecific fenzyme fby f“fooling” fth
fit finstead fof fto fits fnormal ftarget fcell. fThus, fthe ftarget fcells fare fprotected ffrom fthe f action fof f th
fdrug feffect. fThe
alteration fof fcell fmembrane fpermeability, fthe f“fooling” fof fa freceptor fon fthe fcell fwall, fand fthe fe
feffectiveness fof fdrugs fwithin fcells fdo fnot foccur fwith fselective fenzyme f interactions.
DIF: Cognitive fLevel: fComprehension
7. When fadministering fa fnew fmedication fto fa fpatient, fthe fnurse freads fthat fit fis fhighly fprotein fbou
fwill fresult f from fthis fprotein f binding?
a. Renal fexcretion fwill ftake flonger.
b. The fdrug fwill fbe fmetabolized fquickly.
c. The fduration fof faction fof fthe fmedication fwill fbe flonger.
d. The fduration fof faction fof fthe fmedication fwill fbe fshorter.
ANS: fC
Drugs fthat fare fbound fto fplasma fproteins fare fcharacterized fby fa flonger fduration fof faction. fProtei
frenal fexcretion f longer fand fdoes f not fincrease f metabolism fof fthe fdrug. fProtein f binding fof fa fdrug
fof faction f is f longer, f not fshorter.
DIF: Cognitive fLevel: fApplication
8. When fmonitoring fa fpatient fon fan finsulin fdrip fto freduce fblood fglucose flevels, fthe fnurse fnotes fth
fglucose flevel f is fextremely f low, fand fthe fpatient f is f lethargic fand fdifficult fto fawaken. fWhich f adv
fthe fnurse fobserving?
a. An fadverse feffect
b. An fallergic freaction
c. An fidiosyncratic freaction
d. A fpharmacological freaction
ANS: fD
A fpharmacological freaction fis fan fextension fof fthe fdrug’s fnormal feffects fin fthe fbody. fIn fthis fca
fthe fpatient’s f blood fglucose f levels ftoo fmuch. f An fadverse feffect f is fa fpredictable, fwell-known fad
fresults f in f minor for fno fchanges f in fpatient f management. fAn fallergic freaction f(also fknown fas fa f
f involves fthe fpatient’s f immune fsystem. fAn fidiosyncratic freaction fis funexpected fand fis fdefined fa
fabnormal fresponse fto fnormal fdosages fof fa fdrug.
DIF: Cognitive fLevel: fComprehension
9. A fpatient fis fexperiencing fchest fpain fand fneeds fto ftake fa fsublingual fform fof fnitroglycerin. fWher
fthe fpatient fto fplace fthe ftablet?
a. Under fthe ftongue
b. In fthe fspace fbetween fthe fcheek fand fgum
c. At fthe fback fof fthe fthroat, ffor feasy fswallowing
d. On fa fnon-hairy farea fon fthe fchest
ANS: fA
Drugs ftaken fby fthe fsublingual froute fare fplaced funder fthe ftongue. fPlacing fthe ftablet fin fthe fsp
fgum f is fdone f for fthe f buccal froute; fplacing fthe ftablet fat fthe f back fof fthe fthroat f(for feasy fswal
froute; fand fplacing fthe ftablet fon fa f non-hairy farea fon fthe fchest fis fdone f in fthe ftopical for ftransde
DIF: Cognitive fLevel: fComprehension
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Chapter f03: fLegal fand fEthical fConsiderations
Sealock: fLilley’s fPharmacology ffor fCanadian fHealth fCare fPractice, f4th fEdition
MULTIPLE fCHOICE
1. In fthe fdevelopment fof fa fnew fdrug fby fa fpharmaceutical fcompany, fthe fresearcher fmust fensure fth
fexperimental fdrug fstudies fdo fnot fhave funrealistic fexpectations fof fthe fnew fdrug’s fusefulness. fW
finclude fin fthe fdesign fof fthe fstudy fto fprevent fbias fthat f may foccur?
a. A fplacebo
b. Health fCanada fapproval
c. Informed fconsent
d. Efficacy finformation
ANS: f A
To fprevent fbias fthat fmay foccur fas fa fresult fof funrealistic fexpectations fof fan finvestigational fnew
fincorporated finto fthe fstudy. fHealth fCanada fapproval, f if fgiven, fdoes fnot fbe fobtained funtil fafter
fInformed fconsent f is frequired f in fall fdrug fstudies. fEfficacy f information f is f not fdetermined funtil f t
DIF: Cognitive fLevel: fComprehension
2. A fmember fof fan finvestigational fdrug fstudy fteam fis fworking fwith fhealthy fvolunteers fwhose fpart
fdetermine fthe foptimal fdosage frange fand fpharmacokinetics fof fthe fdrug. fIn fwhat ftype fof fstudy f i
fparticipating?
a. Phase fI
b. Phase fII
c. Phase fIII
d. Phase fIV
ANS: f A
Phase fI fstudies finvolve fsmall fnumbers fof fhealthy fvolunteers fto fdetermine fthe foptimal fdosage fran
fpharmacokinetics fof fthe fdrug. fPhases fII, fIII, fand fIV f involve fprogressively f larger f numbers fof f v
fdisease for failment fthat fthe fdrug f is fdesigned fto fdiagnose for ftreat.
DIF: Cognitive fLevel: fApplication
3. A fpatient fhas fa fprescription ffor fa fdrug fclassified fas fSchedule fF. fWhat fimportant finformation fsh
fpatient fabout fobtaining frefills f for fthis f medication?
a. No fprescription frefills fare fpermitted.
b. Refills fmay fbe fobtained fvia ftelephone forder.
c. Refills fare findicated fby fthe fprescriber.
d. The fpatient fmay fhave fno fmore fthan fsix frefills fin fa f12-month fperiod.
ANS: f C
Schedule fF fcontains fa flist fof fdrugs fthat fcan fbe fsold fand frefilled fonly fon fprescription; fprescripti
foften fas f indicated f by fthe fprescriber.
DIF: Cognitive fLevel: fAnalysis
4. A fpatient fhas fbeen fchosen fto fbe fa frecipient fof fan finvestigational fdrug ffor fheart ffailure fand fhas
fconsent. fWhich f is f indicated fby fthe fpatient’s f informed f consent?
a. The fpatient fhas fbeen finformed fof fthe fpossible fbenefits fof fthe fnew ftherapy.
b. The fpatient fwill fbe finformed fof fthe fdetails fof fthe fstudy fas fthe fresearch fcontinues.
c. The fpatient fwill fnot fbe fassured fof freceiving fthe factual fdrug fduring fthe fexperiment.
d. The fpatient fhas freceived fan fexplanation fof fthe fstudy’s fpurpose,
fprocedures, fand fthe fbenefits fand frisks f involved.
ANS: f D
Informed fconsent finvolves fthe fcareful fexplanation fof fthe fpurpose fof fthe fstudy, fprocedures fto fbe
fbenefits fand frisks f involved. fBeing f informed fof fthe fpossible f benefits fof fthe f new ftherapy, f being
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6. What fpotential ffailure fis fidentified fwhen fa fpatient fwith fa fdocumented fpenicillin fallergy freceives
a. Failure fto fassess
b. Failure fto fevaluate
c. Failure fto fensure fsafety
d. Failure fto fidentify fthe fpatient
ANS: fC
Failure fto fensure fsafety fincludes flack fof fadequate fmonitoring, ffailure fto fidentify fpatient fallergie
frelated fto fmedication ftherapy, f inappropriate fdrug fadministration ftechnique, fand f failure fto fimplem
factions fbecause fof f improper fassessment fof fthe fpatient’s fcondition. fWhereas f failure fto fassess for
fto fsee fsignificant fchanges f in fthe fpatient’s fcondition fafter ftaking fa f medication, f failure fto freport f
ftake fa fcomplete fmedication fhistory fand f nursing fassessment/history, fand f failure fto fmonitor fthe fp
fadministration. fFailure fto fidentify fthe fpatient’s f identity f is fa f medication ferror.
DIF: Cognitive fLevel: fApplication
7. Which fstatement fcorrectly fdescribes fdrugs fin fPart fG, fPart fII fof fthe fFood fand fDrugs fAct?
a. They fare fdrugs fwith fhigh fpotential ffor fmisuse fthat fhave fan faccepted fmedical fuse.
b. They fare fdrugs fwith fhigh fpotential ffor fmisuse fthat fdo fnot fhave fan
faccepted f medical fuse.
c. They fare fmedically faccepted fdrugs fthat fmay fcause fmild fphysical for
fpsychological fdependence.
d. They fare fmedically faccepted fdrugs fwith fvery flimited fpotential ffor fcausing
fmild fphysical for fpsychological fdependence.
ANS: fA
Part fG, fPart fII fdrugs fare fthose fwith fhigh fpotential ffor fmisuse fthat fhave fan faccepted fmedical fus
DIF: Cognitive fLevel: fComprehension
8. Miss fKnox, fa f26-year-old, fhas freturned fto fthe fsurgical funit fpost fappendectomy. fThe fphysician f
f(IV) fmorphine ffor fpain. fAccording fto fthe fControlled fDrugs fand fSubstances fACT f(CDSA), fmorp
fwhich fschedule?
a. Schedule fI
b. Schedule fIV
c. Schedule fV
d. Schedule fIII
ANS: fA
The fCDSA fis fbased fon feight fschedules fthat flist fcontrolled fdrugs fand fsubstances fbased fon fpoten
for fhow feasy fthey f are fto fmanufacture finto fillicit fsubstances. fA f summary fof fSchedule fI fcontains
fdrugs, f including fopiates f(opium, f heroin, f morphine, fcocaine), f fentanyls, f and f methamphetamine.
DIF: Cognitive fLevel: fComprehension
MULTIPLE fRESPONSE
1. Which fare felements fof fethical fprinciples fin fnursing fand fhealth fcare faccording fto fthe fCanadian fN
f(CNA) fCode fof fEthics? f(Select fall fthat fapply.)
a. Promoting fjustice
b. Maintaining fanonymity
c. Demonstrating fresponsibility
d. Preserving fdignity
e. Promoting fhealth fand fwell-being
ANS: fA, fD, fE
Elements fof fethical fprinciples fin fnursing fand fhealth fcare faccording fto fthe fCNA fCode fof fEthics
fcompassionate, fcompetent, fand fethical fnursing fcare; fmaintaining fprivacy fand fconfidentiality; fpro
faccountable, fpreserving fdignity, fand fpromoting fand frespecting f informed fdecision f making; fand f p
being.
LILLEY'S PHARMACOLOGY FOR CANADIAN HEALTH CARE PRACTICE
KARA SEALOCK
4th Edition
TEST BANK
, lOMoAR cPSD| 3013804
lOMoAR cPSD| 3013804
Chapter 01: Nursing Practice in Canada and Drug Therapy
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
MULTIPLE CHOICE
1. Which is a judgement about a particular patient’s potential need or problem?
a. A goal
b. An assessment
c. Subjective data
d. A nursing diagnosis
ANS: D
Nursing diagnosis is the phase of the nursing process during which a clinical judgement is made about
heath conditions and life processes or vulnerability for that response.
DIF: Cognitive Level: Knowledge
2. The patient is to receive oral furosemide (Lasix) every day; however, because the patient is unable to sw
medication orally, as ordered. The nurse needs to contact the physician. What type of problem is this?
a. A “right time” problem
b. A “right dose” problem
c. A “right route” problem
d. A “right medication” problem
ANS: C
This is a “right route” problem: the nurse cannot assume the route and must clarify the route with the p
time” problem because the ordered frequency has not changed. This is not a “right dose” problem beca
an inability to swallow. This is not a “right medication” problem because the medication ordered will n
DIF: Cognitive Level: Application
3. The nurse has been monitoring the patient’s progress on his new drug regimen since the first dose and h
of possible adverse effects. What nursing process phase is the nurse practising?
a. Planning
b. Evaluation
c. Implementation
d. Nursing diagnosis
ANS: B
Monitoring the patient’s progress is part of the evaluation phase. Planning, implementation, and nursing
illustrated by this example.
DIF: Cognitive Level: Application
4. The nurse is caring for a patient who has been newly diagnosed with type 1 diabetes mellitus. Which st
outcome criterion for this patient?
a. The patient will follow instructions.
b. The patient will not experience complications.
c. The patient adheres to the new insulin treatment regimen.
d. The patient demonstrates safe insulin self-administration technique.
ANS: D
Having the patient demonstrate safe insulin self-administration technique is a specific and measurable o
instructions and avoiding complications are not specific criteria. Adherence to the new insulin treatmen
and would be difficult to measure.
DIF: Cognitive Level: Application
, lOMoAR cPSD| 3013804
6. The nurse is working during a very busy night shift, and the health care provider has just given the nurs
the telephone, but the nurse does not recall the route. What is the best way for the nurse to avoid medic
a. Recopy the order neatly on the order sheet, with the most common route indicated
b. Consult with the pharmacist for clarification about the most common route
c. Call the health care provider to clarify the route of administration
d. Withhold the drug until the health care provider visits the patient
ANS: C
If a medication order does not include the route, the nurse must ask the health care provider to clarify it
administration.
DIF: Cognitive Level: Application | Cognitive Level: Analysis
7. Which constitutes the traditional Five Rights of medication administration?
a. Right drug, right route, right dose, right time, and right patient
b. Right drug, the right effect, the right route, the right time, and the right patient
c. Right patient, right strength, right diagnosis, right drug, and right route
d. Right patient, right diagnosis, right drug, right route, and right time
ANS: A
The traditional Five Rights of medication administration were considered to be Right drug, Right route
Right patient. Right effect, right strength, and right diagnosis are not part of the traditional Five Rights.
DIF: Cognitive Level: Comprehension
8. What correctly describes the nursing process?
a. Diagnosing, planning, assessing, implementing, and finally evaluating
b. Assessing, then diagnosing, implementing, and ending with evaluating
c. A linear direction that begins with assessing and continues through diagnosing,
planning, and finally implementing
d. An ongoing process that begins with assessing and continues with diagnosing,
planning, implementing, and evaluating
ANS: D
The nursing process is an ongoing, flexible, adaptable, and adjustable five-step process that begins with
through diagnosing, planning, implementing, and finally evaluating, which may then lead back to any o
DIF: Cognitive Level: Application
9. When the nurse is considering the timing of a drug dose, which is most important to assess?
a. The patient’s identification
b. The patient’s weight
c. The patient’s last meal
d. Any drug or food allergies
ANS: C
The pharmacokinetic and pharmacodynamic properties of the drug need to be assessed with regard to a
compatibility issues. The patient’s identification, weight, and drug or food allergies are not affected by
DIF: Cognitive Level: Application
10. The nurse is writing nursing diagnoses for a plan of care. Which reflects the correct format for her nurs
a. Anxiety
b. Anxiety related to new drug therapy
c. Anxiety related to anxious feelings about drug therapy, as evidenced by
statements such as “I’m upset about having to give myself shots”
d. Anxiety related to new drug therapy, as evidenced by statements such as “I’m
upset about having to give myself shots”
ANS: D
Formulation of nursing diagnoses is usually a three-step process. The only complete answer is “Anxiet
, lOMoAR cPSD| 3013804
Chapter 02: Pharmacological Principles
Sealock: Lilley’s Pharmacology for Canadian Health Care Practice, 4th Edition
MULTIPLE CHOICE
1. A patient is receiving two different drugs, which, at their current dose forms and dosages, are both abso
identical amounts. Which term best denotes that the drugs have the same absorption rates?
a. Equivalent
b. Synergistic
c. Compatible
d. Bioequivalent
ANS: D
Two drugs absorbed into the circulation at the same amount (in specific dosage forms) have the same b
bioequivalent. “Equivalent” is incorrect because the term “bioavailability” is used to express the extent
“Synergistic” is incorrect because this term refers to two drugs given together whose resulting effect is
effects of each drug given alone. “Compatible” is incorrect because this term is a general term used to
do not have a chemical reaction when mixed (or given, in the case of drugs) together.
DIF: Cognitive Level: Comprehension
2. A patient is receiving medication via intravenous injection. Which information should the nurse provid
a. The medication will cause fewer adverse effects when given intravenously.
b. The medication will be absorbed slowly into the tissues over time.
c. The medication’s action will begin faster when given intravenously.
d. Most of the drug is inactivated by the liver before it reaches the target area.
ANS: C
Intravenous injections are the fastest route of absorption. The intravenous route does not affect the num
intravenous route is not a slow route of absorption, and the intravenous route does not cause inactivatio
before it reaches the target area.
DIF: Cognitive Level: Comprehension
3. Which is true regarding parenteral drugs?
a. They bypass the first-pass effect.
b. They decrease blood flow to the stomach.
c. They are altered by the presence of food in the stomach.
d. They exert their effects while circulating in the bloodstream.
ANS: A
Drugs given by the parenteral route bypass the first-pass effect, but they still must be absorbed into cell
exert their effects. Enteral drugs (drugs taken orally), not parenteral drugs, decrease blood flow to the s
the presence of food in the stomach. Parenteral drugs must be absorbed into cells and tissues from the c
exert their effects; they do not exert their effects while circulating in the bloodstream.
DIF: Cognitive Level: Analysis
4. A drug’s half-life is best defined as
a. The time it takes for the drug to elicit half its therapeutic response.
b. The time it takes one-half of the original amount of a drug to reach the target
cells.
c. The time it takes one-half of the original amount of a drug to be removed from the
body.
d. The time it takes one-half of the original amount of a drug to be absorbed into the
circulation.
ANS: C
A drug’s half-life is the time it takes for one-half of the original amount of a drug to be removed from t
, lOMoAR cPSD| 3013804
6. A fdrug finteracts fwith fenzymes fby
a. altering fcell fmembrane fpermeability.
b. “fooling” fa freceptor fon fthe fcell fwall.
c. enhancing fthe fdrug’s feffectiveness fwithin fthe fcells.
d. “fooling” fthe fenzyme finto fbinding fwith fit finstead fof fits fnormal ftarget fcell.
ANS: fD
When fdrugs finteract fwith fenzymes, fthey finhibit fthe faction fof fa fspecific fenzyme fby f“fooling” fth
fit finstead fof fto fits fnormal ftarget fcell. fThus, fthe ftarget fcells fare fprotected ffrom fthe f action fof f th
fdrug feffect. fThe
alteration fof fcell fmembrane fpermeability, fthe f“fooling” fof fa freceptor fon fthe fcell fwall, fand fthe fe
feffectiveness fof fdrugs fwithin fcells fdo fnot foccur fwith fselective fenzyme f interactions.
DIF: Cognitive fLevel: fComprehension
7. When fadministering fa fnew fmedication fto fa fpatient, fthe fnurse freads fthat fit fis fhighly fprotein fbou
fwill fresult f from fthis fprotein f binding?
a. Renal fexcretion fwill ftake flonger.
b. The fdrug fwill fbe fmetabolized fquickly.
c. The fduration fof faction fof fthe fmedication fwill fbe flonger.
d. The fduration fof faction fof fthe fmedication fwill fbe fshorter.
ANS: fC
Drugs fthat fare fbound fto fplasma fproteins fare fcharacterized fby fa flonger fduration fof faction. fProtei
frenal fexcretion f longer fand fdoes f not fincrease f metabolism fof fthe fdrug. fProtein f binding fof fa fdrug
fof faction f is f longer, f not fshorter.
DIF: Cognitive fLevel: fApplication
8. When fmonitoring fa fpatient fon fan finsulin fdrip fto freduce fblood fglucose flevels, fthe fnurse fnotes fth
fglucose flevel f is fextremely f low, fand fthe fpatient f is f lethargic fand fdifficult fto fawaken. fWhich f adv
fthe fnurse fobserving?
a. An fadverse feffect
b. An fallergic freaction
c. An fidiosyncratic freaction
d. A fpharmacological freaction
ANS: fD
A fpharmacological freaction fis fan fextension fof fthe fdrug’s fnormal feffects fin fthe fbody. fIn fthis fca
fthe fpatient’s f blood fglucose f levels ftoo fmuch. f An fadverse feffect f is fa fpredictable, fwell-known fad
fresults f in f minor for fno fchanges f in fpatient f management. fAn fallergic freaction f(also fknown fas fa f
f involves fthe fpatient’s f immune fsystem. fAn fidiosyncratic freaction fis funexpected fand fis fdefined fa
fabnormal fresponse fto fnormal fdosages fof fa fdrug.
DIF: Cognitive fLevel: fComprehension
9. A fpatient fis fexperiencing fchest fpain fand fneeds fto ftake fa fsublingual fform fof fnitroglycerin. fWher
fthe fpatient fto fplace fthe ftablet?
a. Under fthe ftongue
b. In fthe fspace fbetween fthe fcheek fand fgum
c. At fthe fback fof fthe fthroat, ffor feasy fswallowing
d. On fa fnon-hairy farea fon fthe fchest
ANS: fA
Drugs ftaken fby fthe fsublingual froute fare fplaced funder fthe ftongue. fPlacing fthe ftablet fin fthe fsp
fgum f is fdone f for fthe f buccal froute; fplacing fthe ftablet fat fthe f back fof fthe fthroat f(for feasy fswal
froute; fand fplacing fthe ftablet fon fa f non-hairy farea fon fthe fchest fis fdone f in fthe ftopical for ftransde
DIF: Cognitive fLevel: fComprehension
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Chapter f03: fLegal fand fEthical fConsiderations
Sealock: fLilley’s fPharmacology ffor fCanadian fHealth fCare fPractice, f4th fEdition
MULTIPLE fCHOICE
1. In fthe fdevelopment fof fa fnew fdrug fby fa fpharmaceutical fcompany, fthe fresearcher fmust fensure fth
fexperimental fdrug fstudies fdo fnot fhave funrealistic fexpectations fof fthe fnew fdrug’s fusefulness. fW
finclude fin fthe fdesign fof fthe fstudy fto fprevent fbias fthat f may foccur?
a. A fplacebo
b. Health fCanada fapproval
c. Informed fconsent
d. Efficacy finformation
ANS: f A
To fprevent fbias fthat fmay foccur fas fa fresult fof funrealistic fexpectations fof fan finvestigational fnew
fincorporated finto fthe fstudy. fHealth fCanada fapproval, f if fgiven, fdoes fnot fbe fobtained funtil fafter
fInformed fconsent f is frequired f in fall fdrug fstudies. fEfficacy f information f is f not fdetermined funtil f t
DIF: Cognitive fLevel: fComprehension
2. A fmember fof fan finvestigational fdrug fstudy fteam fis fworking fwith fhealthy fvolunteers fwhose fpart
fdetermine fthe foptimal fdosage frange fand fpharmacokinetics fof fthe fdrug. fIn fwhat ftype fof fstudy f i
fparticipating?
a. Phase fI
b. Phase fII
c. Phase fIII
d. Phase fIV
ANS: f A
Phase fI fstudies finvolve fsmall fnumbers fof fhealthy fvolunteers fto fdetermine fthe foptimal fdosage fran
fpharmacokinetics fof fthe fdrug. fPhases fII, fIII, fand fIV f involve fprogressively f larger f numbers fof f v
fdisease for failment fthat fthe fdrug f is fdesigned fto fdiagnose for ftreat.
DIF: Cognitive fLevel: fApplication
3. A fpatient fhas fa fprescription ffor fa fdrug fclassified fas fSchedule fF. fWhat fimportant finformation fsh
fpatient fabout fobtaining frefills f for fthis f medication?
a. No fprescription frefills fare fpermitted.
b. Refills fmay fbe fobtained fvia ftelephone forder.
c. Refills fare findicated fby fthe fprescriber.
d. The fpatient fmay fhave fno fmore fthan fsix frefills fin fa f12-month fperiod.
ANS: f C
Schedule fF fcontains fa flist fof fdrugs fthat fcan fbe fsold fand frefilled fonly fon fprescription; fprescripti
foften fas f indicated f by fthe fprescriber.
DIF: Cognitive fLevel: fAnalysis
4. A fpatient fhas fbeen fchosen fto fbe fa frecipient fof fan finvestigational fdrug ffor fheart ffailure fand fhas
fconsent. fWhich f is f indicated fby fthe fpatient’s f informed f consent?
a. The fpatient fhas fbeen finformed fof fthe fpossible fbenefits fof fthe fnew ftherapy.
b. The fpatient fwill fbe finformed fof fthe fdetails fof fthe fstudy fas fthe fresearch fcontinues.
c. The fpatient fwill fnot fbe fassured fof freceiving fthe factual fdrug fduring fthe fexperiment.
d. The fpatient fhas freceived fan fexplanation fof fthe fstudy’s fpurpose,
fprocedures, fand fthe fbenefits fand frisks f involved.
ANS: f D
Informed fconsent finvolves fthe fcareful fexplanation fof fthe fpurpose fof fthe fstudy, fprocedures fto fbe
fbenefits fand frisks f involved. fBeing f informed fof fthe fpossible f benefits fof fthe f new ftherapy, f being
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6. What fpotential ffailure fis fidentified fwhen fa fpatient fwith fa fdocumented fpenicillin fallergy freceives
a. Failure fto fassess
b. Failure fto fevaluate
c. Failure fto fensure fsafety
d. Failure fto fidentify fthe fpatient
ANS: fC
Failure fto fensure fsafety fincludes flack fof fadequate fmonitoring, ffailure fto fidentify fpatient fallergie
frelated fto fmedication ftherapy, f inappropriate fdrug fadministration ftechnique, fand f failure fto fimplem
factions fbecause fof f improper fassessment fof fthe fpatient’s fcondition. fWhereas f failure fto fassess for
fto fsee fsignificant fchanges f in fthe fpatient’s fcondition fafter ftaking fa f medication, f failure fto freport f
ftake fa fcomplete fmedication fhistory fand f nursing fassessment/history, fand f failure fto fmonitor fthe fp
fadministration. fFailure fto fidentify fthe fpatient’s f identity f is fa f medication ferror.
DIF: Cognitive fLevel: fApplication
7. Which fstatement fcorrectly fdescribes fdrugs fin fPart fG, fPart fII fof fthe fFood fand fDrugs fAct?
a. They fare fdrugs fwith fhigh fpotential ffor fmisuse fthat fhave fan faccepted fmedical fuse.
b. They fare fdrugs fwith fhigh fpotential ffor fmisuse fthat fdo fnot fhave fan
faccepted f medical fuse.
c. They fare fmedically faccepted fdrugs fthat fmay fcause fmild fphysical for
fpsychological fdependence.
d. They fare fmedically faccepted fdrugs fwith fvery flimited fpotential ffor fcausing
fmild fphysical for fpsychological fdependence.
ANS: fA
Part fG, fPart fII fdrugs fare fthose fwith fhigh fpotential ffor fmisuse fthat fhave fan faccepted fmedical fus
DIF: Cognitive fLevel: fComprehension
8. Miss fKnox, fa f26-year-old, fhas freturned fto fthe fsurgical funit fpost fappendectomy. fThe fphysician f
f(IV) fmorphine ffor fpain. fAccording fto fthe fControlled fDrugs fand fSubstances fACT f(CDSA), fmorp
fwhich fschedule?
a. Schedule fI
b. Schedule fIV
c. Schedule fV
d. Schedule fIII
ANS: fA
The fCDSA fis fbased fon feight fschedules fthat flist fcontrolled fdrugs fand fsubstances fbased fon fpoten
for fhow feasy fthey f are fto fmanufacture finto fillicit fsubstances. fA f summary fof fSchedule fI fcontains
fdrugs, f including fopiates f(opium, f heroin, f morphine, fcocaine), f fentanyls, f and f methamphetamine.
DIF: Cognitive fLevel: fComprehension
MULTIPLE fRESPONSE
1. Which fare felements fof fethical fprinciples fin fnursing fand fhealth fcare faccording fto fthe fCanadian fN
f(CNA) fCode fof fEthics? f(Select fall fthat fapply.)
a. Promoting fjustice
b. Maintaining fanonymity
c. Demonstrating fresponsibility
d. Preserving fdignity
e. Promoting fhealth fand fwell-being
ANS: fA, fD, fE
Elements fof fethical fprinciples fin fnursing fand fhealth fcare faccording fto fthe fCNA fCode fof fEthics
fcompassionate, fcompetent, fand fethical fnursing fcare; fmaintaining fprivacy fand fconfidentiality; fpro
faccountable, fpreserving fdignity, fand fpromoting fand frespecting f informed fdecision f making; fand f p
being.
