Embryology
Heart morphogenesis is 1stfunctional organ invertebrateembryos
beats spontaneouslybyweek 4 ofdevelopment
Cardiaclooping 10 tubeloops to establish L R polarity
begins in week 4 development
Defect in L R Dynein Dextocardia as seen in Kartagenersyndrome
I ciliaryDyskinesia
Septationof chambers
Atria complex
1 septumprimumgrowstowardendocardial
cushions narrowingforamenprimum 10
2 foramensecundum 20 forms in
septumprimum foramen10regresses
3 septumsecundum 20 develops on R side ofseptumprimum 10
residualforamen foramen ovale
fft
4 septuntrsetunatimunizitiplandisntisiers mist ramensecundum120
S remainingportionofseptumprimum 10 forms 1 way valve of
foramen ovale
6 septumprimum 10 closesagainstseptumsecundum 20 sealingthe
foramen soonafterbirth d t T LA pressure I RA pressure
7 septumsecundum 20 septumprimum 10 fuse during
infancyearlychildhood forming atrial septum
Patentforamenovale caused by failure of septumprimum 10 t
septum secundum 20 tofusepost birth
most left untreated
can paradoxical emboli venousthromboembolienteringcirculation
, ventricles verysimple
1 muscularintraventricular septumforms
2 aorticopulm septumrotates fuses w
muse vent septum closing
intraventricularforamen
3 growth ofendocardialcushion separates atria fromvents and
contributes to both atrial septation membranous portion of
intraventricular septum
outflowtract formation
neuralcrest endocardialcellmigration truncal bulbar ridgesthat
spiral fuseto form
asc aorta palm trunk formation a aorticopulm septum
Valvedevelopment
aortic palm SL deriv from endocardialcushions
mitral tri AV deriv from fused endocardial cushions
of AV canal
Heartembryology
embryonic structure gives rise to
truncusarteriosus asc aorta palm trunk
bulbus cordis smoothparts outflowtract of
L t R vents
primitive 10 vent trabeculatedpartof Lt R vents
primitive 10 atria trabeculatedpartof Lt 12 atria
L horn ofsinus venous coronary sinus
R hornofsinus venous smooth part of R atrium
sinus venarum
endocardial cushion atrial septum memberintravent septum
AV SL valves
R common cardinal v Rant SVC
cardinal vein
Post subcardinal supracardinal IVC
veins
primitive110 palmvein smooth partof left atrium
Heart morphogenesis is 1stfunctional organ invertebrateembryos
beats spontaneouslybyweek 4 ofdevelopment
Cardiaclooping 10 tubeloops to establish L R polarity
begins in week 4 development
Defect in L R Dynein Dextocardia as seen in Kartagenersyndrome
I ciliaryDyskinesia
Septationof chambers
Atria complex
1 septumprimumgrowstowardendocardial
cushions narrowingforamenprimum 10
2 foramensecundum 20 forms in
septumprimum foramen10regresses
3 septumsecundum 20 develops on R side ofseptumprimum 10
residualforamen foramen ovale
fft
4 septuntrsetunatimunizitiplandisntisiers mist ramensecundum120
S remainingportionofseptumprimum 10 forms 1 way valve of
foramen ovale
6 septumprimum 10 closesagainstseptumsecundum 20 sealingthe
foramen soonafterbirth d t T LA pressure I RA pressure
7 septumsecundum 20 septumprimum 10 fuse during
infancyearlychildhood forming atrial septum
Patentforamenovale caused by failure of septumprimum 10 t
septum secundum 20 tofusepost birth
most left untreated
can paradoxical emboli venousthromboembolienteringcirculation
, ventricles verysimple
1 muscularintraventricular septumforms
2 aorticopulm septumrotates fuses w
muse vent septum closing
intraventricularforamen
3 growth ofendocardialcushion separates atria fromvents and
contributes to both atrial septation membranous portion of
intraventricular septum
outflowtract formation
neuralcrest endocardialcellmigration truncal bulbar ridgesthat
spiral fuseto form
asc aorta palm trunk formation a aorticopulm septum
Valvedevelopment
aortic palm SL deriv from endocardialcushions
mitral tri AV deriv from fused endocardial cushions
of AV canal
Heartembryology
embryonic structure gives rise to
truncusarteriosus asc aorta palm trunk
bulbus cordis smoothparts outflowtract of
L t R vents
primitive 10 vent trabeculatedpartof Lt R vents
primitive 10 atria trabeculatedpartof Lt 12 atria
L horn ofsinus venous coronary sinus
R hornofsinus venous smooth part of R atrium
sinus venarum
endocardial cushion atrial septum memberintravent septum
AV SL valves
R common cardinal v Rant SVC
cardinal vein
Post subcardinal supracardinal IVC
veins
primitive110 palmvein smooth partof left atrium
