TEST BANK Test Bank For Basic and Clinical Pharmacology 14th Edition by Bertram Katzung
Table of Contents:
Section I: Basic principles
Chapter 1: Introduction: the nature of drugs & drug development & regulation
BASIC AND CLINICAL
Chapter 2: Drug receptors & pharmacodynamics
Chapter 3: Pharmacokinetics & pharmacodynamics: rational dosing & the time course of
drug action
PHARMACOLOGY
Chapter 4: Drug biotransformation
Chapter 5: Pharmacogenomics
Section II: Autonomic drugs
Chapter 6: Introduction to autonomic pharmacology
14th Edition Chapter 7: Cholinoceptor-activating & cholinesterase-inhibiting drugs
Chapter 8: Cholinoceptor-blocking drugs
By: Bertram Katzung Chapter 9: Adrenoceptor agonists & sympathomimetic drugs
Chapter 10: Adrenoceptor antagonist drugs
Section III: Cardiovascular-renal drugs
Chapter 11: Antihypertensive agents
Chapter 12: Vasodilators & the treatment of angina pectoris
Chapter 13: Drugs used in heart failure
Chapter 14: Agents used in cardiac arrhythmias
Chapter 15: Diuretic agents
Section IV: Drugs with important actions on smooth muscle
Chapter 16: Histamine, serotonin, & the ergot alkaloids
Chapter 17: Vasoactive peptides
Chapter 18: The Eicosanoids: prostaglandins, thromboxanes, leukotrienes, & related
compounds
Chapter 19: Nitric oxide
Chapter 20: Drugs used in asthma
Section V: Drugs that act in the central nervous system
Chapter 21: Introduction to the pharmacology of cns drugs
Chapter 22: Sedative-hypnotic drugs
Chapter 23: The Alcohols
Chapter 24: Antiseizure drugs
Chapter 25: General anesthetics
Chapter 26: Local anesthetics
Chapter 27: Skeletal muscle relaxants
Chapter 28: Pharmacologic management of parkinsonism & other movement disorders
Chapter 29: Antipsychotic agents & lithium
Chapter 30: Antidepressant agents
Chapter 31: Opioid agonists & antagonists
TEST BANK
Chapter 32: Drugs of abuse
,Section VI: Drugs used to treat diseases of the blood, inflammation, & gout Test Bank For Basic and Clinical Pharmacology 14th Edition by Bertram Katzung
Chapter 33: Agents used in cytopenias; hematopoietic growth factors Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
Chapter 34: Drugs used in disorders of coagulation
Chapter 35: Agents used in dyslipidemia
Chapter 36: Nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic 1. A nurse working in radiology administers iodine to a patient who is having a
drugs, nonopioid analgesics, & drugs used in gout computed tomography (CT) scan. The nurse working on the oncology unit
Section VII: Endocrine drugs
administers chemotherapy to patients who have cancer. At the Public Health
Chapter 37: Hypothalamic & pituitary hormones
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
Chapter 38: Thyroid & antithyroid drugs
a 14-month-old child as a routine immunization. Which branch of
Chapter 39: Adrenocorticosteroids & adrenocortical antagonists
pharmacology best describes the actions of all three nurses?
Chapter 40: The Gonadal hormones & inhibitors
Chapter 41: Pancreatic hormones & antidiabetic drugs A) Pharmacoeconomics
Chapter 42: Agents that affect bone mineral homeostasis
Section VIII: Chemotherapeutic drugs B) Pharmacotherapeutics
Chapter 43: Beta-lactam & other cell wall- & membrane-active antibiotics C) Pharmacodynamics
Chapter 44: Tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, &
oxazolidinones D) Pharmacokinetics
Chapter 45: Aminoglycosides & spectinomycin
Ans: B
Chapter 46: Sulfonamides, trimethoprim, & quinolones
Chapter 47: Antimycobacterial drugs Feedback:
Chapter 48: Antifungal agents
Chapter 49: Antiviral agents Pharmacology is the study of the biologic effects of chemicals. Nurses are
Chapter 50: Miscellaneous antimicrobial agents; disinfectants, antiseptics, & sterilants involved with clinical pharmacology or pharmacotherapeutics, which is a
Chapter 51: Clinical use of antimicrobial agents branch of pharmacology that deals with the uses of drugs to treat, prevent,
Chapter 52: Antiprotozoal drugs and diagnose disease. The radiology nurse is administering a drug to help
Chapter 53: Clinical pharmacology of the antihelminthic drugs diagnose a disease. The oncology nurse is administering a drug to help treat a
Chapter 54: Cancer chemotherapy disease. Pharmacoeconomics includes any costs involved in drug therapy.
Chapter 55: Immunopharmacology Pharmacodynamics involves how a drug affects the body and
Section IX: Toxicology pharmacokinetics is how the body acts on the body.
Chapter 56: Introduction to toxicology: occupational & environmental
Chapter 57: Heavy metal intoxication & chelators
Chapter 58: Management of the poisoned patient 2. A physician has ordered intramuscular (IM) injections of morphine, a
Section X: Special topics narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
Chapter 59: Special aspects of perinatal & pediatric pharmacology The nurse is aware this drug has a high abuse potential. Under what category
Chapter 60: Special aspects of geriatric pharmacology would morphine be classified?
Chapter 61: Dermatologic pharmacology
A) Schedule I
Chapter 62: Drugs used in the treatment of gastrointestinal diseases
Chapter 63: Therapeutic & toxic potential of over-the-counter agents B) Schedule II
Chapter 64: Dietary supplements & herbal medications
Chapter 65: Rational prescribing & prescription writing
Chapter 66: Important drug interactions & their mechanisms
WWW.THENURSINGMASTERY.COM
,C) Schedule III B) Critical concentration
D) Schedule IV C) Distribution
Ans: B D) Half-life
Feedback: Ans: A
Narcotics with a high abuse potential are classified as Schedule II drugs Feedback:
because of severe dependence liability. Schedule I drugs have high abuse
Bioavailability is the portion of a dose of a drug that reaches the systemic
potential and no accepted medical use. Schedule III drugs have a lesser
circulation and is available to act on body cells. Binders used in a generic
abuse potential than II and an accepted medical use. Schedule IV drugs have
drug may not be the same as those used in the brand name drug. Therefore,
low abuse potential and limited dependence liability.
the way the body breaks down and uses the drug may differ, which may
eliminate a generic drug substitution. Critical concentration is the amount of
3. When involved in phase III drug evaluation studies, what responsibilities a drug that is needed to cause a therapeutic effect and should not differ
would the nurse have? between generic and brand name medications. Distribution is the phase of
pharmacokinetics, which involves the movement of a drug to the bodys
A) Working with animals who are given experimental drugs tissues and is the same in generic and brand name drugs. A drugs half-life is
B) Choosing appropriate patients to be involved in the drug study the time it takes for the amount of drug to decrease to half the peak level,
which should not change when substituting a generic medication.
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug 5. A nurse is assessing the patients home medication use. After listening to the
Ans: C patient list current medications, the nurse asks what priority question?
Feedback: A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
Phase III studies involve use of a drug in a vast clinical population in which
patients are asked to record any symptoms they experience while taking the C) Are these medications safe to take during pregnancy?
drugs. Nurses may be responsible for helping collect and analyze the
information to be shared with the Food and Drug Administration (FDA) but D) Do you take any over-the-counter medications?
would not conduct research independently because nurses do not prescribe Ans: D
medications. Use of animals in drug testing is done in the preclinical trials.
Select patients who are involved in phase II studies to participate in studies Feedback:
where the participants have the disease the drug is intended to treat. These
It is important for the nurse to specifically question use of over-the-counter
patients are monitored closely for drug action and adverse effects. Phase I
medications because patients may not consider them important. The patient
studies involve healthy human volunteers who are usually paid for their
is unlikely to know the meaning of orphan drugs unless they too are health
participation. Nurses may observe for adverse effects and toxicity.
care providers. Safety during pregnancy, use of a generic medication, or
classification of orphan drugs are things the patient would be unable to
4. What concept is considered when generic drugs are substituted for brand answer but could be found in reference books if the nurse wishes to research
name drugs? them.
A) Bioavailability
WWW.THENURSINGMASTERY.COM WWW.THENURSINGMASTERY.COM
, 6. After completing a course on pharmacology for nurses, what will the nurse Feedback:
know?
Category B indicates that animal studies have not demonstrated a risk to the
A) Everything necessary for safe and effective medication administration fetus. However, there have not been adequate studies in pregnant women to
B) Current pharmacologic therapy; the nurse will not require ongoing demonstrate risk to a fetus during the first trimester of pregnancy and no
education for 5 years. evidence of risk in later trimesters. Category A indicates that adequate
studies in pregnant women have not demonstrated a risk to the fetus in the
C) General drug information; the nurse can consult a drug guide for specific first trimester or in later trimesters. Category C indicates that animal studies
drug information. have shown an adverse effect on the fetus, but no adequate studies in
humans. Category D reveals evidence of human fetal risk, but the potential
D) The drug actions that are associated with each classification of
benefits from the use of the drugs in pregnant women may outweigh
medication
potential risks.
Ans: C
Feedback: 8. Discharge planning for patients leaving the hospital should include
instructions on the use of over-the-counter (OTC) drugs. Which comment by
After completing a pharmacology course nurses will have general drug
the patient would demonstrate a good understanding of OTC drugs?
information needed for safe and effective medication administration but will
need to consult a drug guide for specific drug information before A) OTC drugs are safe and do not cause adverse effects if taken properly.
administering any medication. Pharmacology is constantly changing, with
B) OTC drugs have been around for years and have not been tested by the
new drugs entering the market and new uses for existing drugs identified.
Food and Drug Administration (FDA).
Continuing education in pharmacology is essential to safe practice. Nurses
tend to become familiar with the medications they administer most often, but C) OTC drugs are different from any drugs available by prescription and
there will always be a need to research new drugs and also those the nurse is cost less.
not familiar with because no nurse knows all medications.
D) OTC drugs could cause serious harm if not taken according to directions.
Ans: D
7. A nurse is instructing a pregnant patient concerning the potential risk to her
fetus from a Pregnancy Category B drug. What would the nurse inform the Feedback:
patient?
It is important to follow package directions because OTCs are medications
A) Adequate studies in pregnant women have demonstrated there is no risk that can cause serious harm if not taken properly. OTCs are drugs that have
to the fetus. been determined to be safe when taken as directed; however, all drugs can
B) Animal studies have not demonstrated a risk to the fetus, but there have produce adverse effects even when taken properly. They may have originally
been no adequate studies in pregnant women. been prescription drugs that were tested by the FDA or they may have been
grandfathered in when the FDA laws changed. OTC education should
C) Animal studies have shown an adverse effect on the fetus, but there are always be included as a part of the hospital discharge instructions.
no adequate studies in pregnant women.
D) There is evidence of human fetal risk, but the potential benefits from use 9. What would be the best source of drug information for a nurse?
of the drug may be acceptable despite potential risks.
A) Drug Facts and Comparisons
Ans: B
B) A nurses drug guide
WWW.THENURSINGMASTERY.COM WWW.THENURSINGMASTERY.COM
Table of Contents:
Section I: Basic principles
Chapter 1: Introduction: the nature of drugs & drug development & regulation
BASIC AND CLINICAL
Chapter 2: Drug receptors & pharmacodynamics
Chapter 3: Pharmacokinetics & pharmacodynamics: rational dosing & the time course of
drug action
PHARMACOLOGY
Chapter 4: Drug biotransformation
Chapter 5: Pharmacogenomics
Section II: Autonomic drugs
Chapter 6: Introduction to autonomic pharmacology
14th Edition Chapter 7: Cholinoceptor-activating & cholinesterase-inhibiting drugs
Chapter 8: Cholinoceptor-blocking drugs
By: Bertram Katzung Chapter 9: Adrenoceptor agonists & sympathomimetic drugs
Chapter 10: Adrenoceptor antagonist drugs
Section III: Cardiovascular-renal drugs
Chapter 11: Antihypertensive agents
Chapter 12: Vasodilators & the treatment of angina pectoris
Chapter 13: Drugs used in heart failure
Chapter 14: Agents used in cardiac arrhythmias
Chapter 15: Diuretic agents
Section IV: Drugs with important actions on smooth muscle
Chapter 16: Histamine, serotonin, & the ergot alkaloids
Chapter 17: Vasoactive peptides
Chapter 18: The Eicosanoids: prostaglandins, thromboxanes, leukotrienes, & related
compounds
Chapter 19: Nitric oxide
Chapter 20: Drugs used in asthma
Section V: Drugs that act in the central nervous system
Chapter 21: Introduction to the pharmacology of cns drugs
Chapter 22: Sedative-hypnotic drugs
Chapter 23: The Alcohols
Chapter 24: Antiseizure drugs
Chapter 25: General anesthetics
Chapter 26: Local anesthetics
Chapter 27: Skeletal muscle relaxants
Chapter 28: Pharmacologic management of parkinsonism & other movement disorders
Chapter 29: Antipsychotic agents & lithium
Chapter 30: Antidepressant agents
Chapter 31: Opioid agonists & antagonists
TEST BANK
Chapter 32: Drugs of abuse
,Section VI: Drugs used to treat diseases of the blood, inflammation, & gout Test Bank For Basic and Clinical Pharmacology 14th Edition by Bertram Katzung
Chapter 33: Agents used in cytopenias; hematopoietic growth factors Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
Chapter 34: Drugs used in disorders of coagulation
Chapter 35: Agents used in dyslipidemia
Chapter 36: Nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic 1. A nurse working in radiology administers iodine to a patient who is having a
drugs, nonopioid analgesics, & drugs used in gout computed tomography (CT) scan. The nurse working on the oncology unit
Section VII: Endocrine drugs
administers chemotherapy to patients who have cancer. At the Public Health
Chapter 37: Hypothalamic & pituitary hormones
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
Chapter 38: Thyroid & antithyroid drugs
a 14-month-old child as a routine immunization. Which branch of
Chapter 39: Adrenocorticosteroids & adrenocortical antagonists
pharmacology best describes the actions of all three nurses?
Chapter 40: The Gonadal hormones & inhibitors
Chapter 41: Pancreatic hormones & antidiabetic drugs A) Pharmacoeconomics
Chapter 42: Agents that affect bone mineral homeostasis
Section VIII: Chemotherapeutic drugs B) Pharmacotherapeutics
Chapter 43: Beta-lactam & other cell wall- & membrane-active antibiotics C) Pharmacodynamics
Chapter 44: Tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, &
oxazolidinones D) Pharmacokinetics
Chapter 45: Aminoglycosides & spectinomycin
Ans: B
Chapter 46: Sulfonamides, trimethoprim, & quinolones
Chapter 47: Antimycobacterial drugs Feedback:
Chapter 48: Antifungal agents
Chapter 49: Antiviral agents Pharmacology is the study of the biologic effects of chemicals. Nurses are
Chapter 50: Miscellaneous antimicrobial agents; disinfectants, antiseptics, & sterilants involved with clinical pharmacology or pharmacotherapeutics, which is a
Chapter 51: Clinical use of antimicrobial agents branch of pharmacology that deals with the uses of drugs to treat, prevent,
Chapter 52: Antiprotozoal drugs and diagnose disease. The radiology nurse is administering a drug to help
Chapter 53: Clinical pharmacology of the antihelminthic drugs diagnose a disease. The oncology nurse is administering a drug to help treat a
Chapter 54: Cancer chemotherapy disease. Pharmacoeconomics includes any costs involved in drug therapy.
Chapter 55: Immunopharmacology Pharmacodynamics involves how a drug affects the body and
Section IX: Toxicology pharmacokinetics is how the body acts on the body.
Chapter 56: Introduction to toxicology: occupational & environmental
Chapter 57: Heavy metal intoxication & chelators
Chapter 58: Management of the poisoned patient 2. A physician has ordered intramuscular (IM) injections of morphine, a
Section X: Special topics narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
Chapter 59: Special aspects of perinatal & pediatric pharmacology The nurse is aware this drug has a high abuse potential. Under what category
Chapter 60: Special aspects of geriatric pharmacology would morphine be classified?
Chapter 61: Dermatologic pharmacology
A) Schedule I
Chapter 62: Drugs used in the treatment of gastrointestinal diseases
Chapter 63: Therapeutic & toxic potential of over-the-counter agents B) Schedule II
Chapter 64: Dietary supplements & herbal medications
Chapter 65: Rational prescribing & prescription writing
Chapter 66: Important drug interactions & their mechanisms
WWW.THENURSINGMASTERY.COM
,C) Schedule III B) Critical concentration
D) Schedule IV C) Distribution
Ans: B D) Half-life
Feedback: Ans: A
Narcotics with a high abuse potential are classified as Schedule II drugs Feedback:
because of severe dependence liability. Schedule I drugs have high abuse
Bioavailability is the portion of a dose of a drug that reaches the systemic
potential and no accepted medical use. Schedule III drugs have a lesser
circulation and is available to act on body cells. Binders used in a generic
abuse potential than II and an accepted medical use. Schedule IV drugs have
drug may not be the same as those used in the brand name drug. Therefore,
low abuse potential and limited dependence liability.
the way the body breaks down and uses the drug may differ, which may
eliminate a generic drug substitution. Critical concentration is the amount of
3. When involved in phase III drug evaluation studies, what responsibilities a drug that is needed to cause a therapeutic effect and should not differ
would the nurse have? between generic and brand name medications. Distribution is the phase of
pharmacokinetics, which involves the movement of a drug to the bodys
A) Working with animals who are given experimental drugs tissues and is the same in generic and brand name drugs. A drugs half-life is
B) Choosing appropriate patients to be involved in the drug study the time it takes for the amount of drug to decrease to half the peak level,
which should not change when substituting a generic medication.
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug 5. A nurse is assessing the patients home medication use. After listening to the
Ans: C patient list current medications, the nurse asks what priority question?
Feedback: A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
Phase III studies involve use of a drug in a vast clinical population in which
patients are asked to record any symptoms they experience while taking the C) Are these medications safe to take during pregnancy?
drugs. Nurses may be responsible for helping collect and analyze the
information to be shared with the Food and Drug Administration (FDA) but D) Do you take any over-the-counter medications?
would not conduct research independently because nurses do not prescribe Ans: D
medications. Use of animals in drug testing is done in the preclinical trials.
Select patients who are involved in phase II studies to participate in studies Feedback:
where the participants have the disease the drug is intended to treat. These
It is important for the nurse to specifically question use of over-the-counter
patients are monitored closely for drug action and adverse effects. Phase I
medications because patients may not consider them important. The patient
studies involve healthy human volunteers who are usually paid for their
is unlikely to know the meaning of orphan drugs unless they too are health
participation. Nurses may observe for adverse effects and toxicity.
care providers. Safety during pregnancy, use of a generic medication, or
classification of orphan drugs are things the patient would be unable to
4. What concept is considered when generic drugs are substituted for brand answer but could be found in reference books if the nurse wishes to research
name drugs? them.
A) Bioavailability
WWW.THENURSINGMASTERY.COM WWW.THENURSINGMASTERY.COM
, 6. After completing a course on pharmacology for nurses, what will the nurse Feedback:
know?
Category B indicates that animal studies have not demonstrated a risk to the
A) Everything necessary for safe and effective medication administration fetus. However, there have not been adequate studies in pregnant women to
B) Current pharmacologic therapy; the nurse will not require ongoing demonstrate risk to a fetus during the first trimester of pregnancy and no
education for 5 years. evidence of risk in later trimesters. Category A indicates that adequate
studies in pregnant women have not demonstrated a risk to the fetus in the
C) General drug information; the nurse can consult a drug guide for specific first trimester or in later trimesters. Category C indicates that animal studies
drug information. have shown an adverse effect on the fetus, but no adequate studies in
humans. Category D reveals evidence of human fetal risk, but the potential
D) The drug actions that are associated with each classification of
benefits from the use of the drugs in pregnant women may outweigh
medication
potential risks.
Ans: C
Feedback: 8. Discharge planning for patients leaving the hospital should include
instructions on the use of over-the-counter (OTC) drugs. Which comment by
After completing a pharmacology course nurses will have general drug
the patient would demonstrate a good understanding of OTC drugs?
information needed for safe and effective medication administration but will
need to consult a drug guide for specific drug information before A) OTC drugs are safe and do not cause adverse effects if taken properly.
administering any medication. Pharmacology is constantly changing, with
B) OTC drugs have been around for years and have not been tested by the
new drugs entering the market and new uses for existing drugs identified.
Food and Drug Administration (FDA).
Continuing education in pharmacology is essential to safe practice. Nurses
tend to become familiar with the medications they administer most often, but C) OTC drugs are different from any drugs available by prescription and
there will always be a need to research new drugs and also those the nurse is cost less.
not familiar with because no nurse knows all medications.
D) OTC drugs could cause serious harm if not taken according to directions.
Ans: D
7. A nurse is instructing a pregnant patient concerning the potential risk to her
fetus from a Pregnancy Category B drug. What would the nurse inform the Feedback:
patient?
It is important to follow package directions because OTCs are medications
A) Adequate studies in pregnant women have demonstrated there is no risk that can cause serious harm if not taken properly. OTCs are drugs that have
to the fetus. been determined to be safe when taken as directed; however, all drugs can
B) Animal studies have not demonstrated a risk to the fetus, but there have produce adverse effects even when taken properly. They may have originally
been no adequate studies in pregnant women. been prescription drugs that were tested by the FDA or they may have been
grandfathered in when the FDA laws changed. OTC education should
C) Animal studies have shown an adverse effect on the fetus, but there are always be included as a part of the hospital discharge instructions.
no adequate studies in pregnant women.
D) There is evidence of human fetal risk, but the potential benefits from use 9. What would be the best source of drug information for a nurse?
of the drug may be acceptable despite potential risks.
A) Drug Facts and Comparisons
Ans: B
B) A nurses drug guide
WWW.THENURSINGMASTERY.COM WWW.THENURSINGMASTERY.COM
