PHARMACOLOGY ASSESSMENT
EXAMS WITH CORRECT
QUESTIONS AND ANSWERS.
What is a bland aerosol? - ✔️✔️Non-medicated aerosols such as sterile water
Advantages of the inhalation route - ✔️✔S️ maller required doses.
Quick drug response.
Fewer, less severe side effects.
Painless and convenient.
Disadvantages of the inhalation route - ✔️✔D
️ ifficult to deliver consistent precise dose.
Requires patient compliance and education.
Equipment and maintenance.
What is an aerosol? - ✔️✔️Suspension of solid or liquid particles within a gas.
What is aerosol therapy? - ✔️✔D
️ elivers either solid or liquid aerosol particles into the respiratory tract
for therapeutic purposes.
What are three main goals of aerosol therapy? - ✔️✔H
️ umidify inspired gas.
Improve the mobilization and elimination of secretions.
Deliver medications to the respiratory tract.
What is a medicated aerosol? - ✔️✔️A suspension of a solid or liquid drug in a carrier gas.
, What are the four factors that influence drug delivery within the lungs? - ✔️✔️Stability.
Penetration.
Deposition.
Inertial impact.
What is stability? - ✔️✔️Tendency of an aerosol to remain in suspension.
What is penetration? - ✔️✔H
️ ow far into the lungs the aerosol particles travel.
What is deposition? - ✔️✔️The aerosol particles falling out of suspension.
What is inertial impact? - ✔️✔A ️ function of particle size and velocity. Inertial impaction increases with
larger size and higher velocities.
What is a micron? - ✔️✔️1 millionth of a meter.
What size of particles would be used for a nasal spray? - ✔️✔️10 to 15 microns.
What size of particles would be used to penetrate the large bronchi? - ✔️✔️5 to 10 microns.
What size particles would be used to penetrate the lower airways? - ✔️✔️1 to 5 microns.
Why don't medications contains particle sizes under 1 micron? - ✔️✔️Because they are so stable they
never fall out of suspension for absorption and are exhaled.
Factors that determine particle size in aerosols - ✔️✔D
️ esign of nebulizer.
Flow and density of gas.
Dead volume of the nebulizer.
The volume of diluent used.