II! II! II! II! II! II!
Pathophysiology, Canadian Edition,
II! II! II! II!
2nd Edition by Kelly Power-Kean,
II! II! II! II! II!
Chapter 1 - 42 II! II! II! II!
,Table of Contents II! II!
PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
II! II! II! II! II!
Unit 1: The Cell
II! II! II!
1. Cellular Biology II!
2. Genes and Genetic Diseases
II! II! II!
3. Epigenetics and Disease II! II!
4. Altered Cellular and Tissue Biology
II! II! II! II!
5. Fluids and Electrolytes, Acids and Bases
II! II! II! II! II!
Unit 2: Mechanisms of Self-Defense
II! II! II! II!
6. Innate Immunity: Inflammation and Wound Healing
II! II! II! II! II!
7. Adaptive Immunity II!
8. Infection and Defects in Mechanisms of DefenseII! II! II! II! II! II!
9. Stress and Disease II! II!
Unit 3: Cellular Proliferation: Cancer
II! II! II! II!
10. Biology of Cancer II! II!
11. Cancer Epidemiology II!
12. Cancer in Children and Adolescents II! II! II! II!
PART TWO: BODY SYSTEMS AND DISEASES
II! II! II! II! II!
Unit 4: The Neurologic System
II! II! II! II!
13. Structure and Function of the Neurologic System II! II! II! II! II! II!
14. Pain, Temperature, Sleep, and Sensory Function
II! II! II! II! II!
15. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function II! II! II! II! II! II! II! II!
16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
II! II! II! II! II! II! II! II! II! II!
17. Alterations of Neurologic Function in Children II! II! II! II! II!
Unit 5: The Endocrine System
II! II! II! II!
18. Mechanisms of Hormonal Regulation II! II! II!
19. Alterations of Hormonal Regulation II! II! II!
Unit 6: The Hematologic System
II! II! II! II!
20. Structure and Function of the Hematologic System II! II! II! II! II! II!
21. Alterations in Hematologic Function II! II! II!
22. Alterations of Hematologic Function in Children II! II! II! II! II!
Unit 7: The Cardiovascular and Lymphatic Systems
II! II! II! II! II! II!
23. Structure and Function of the Cardiovascular and Lymphatic Systems
II! II! II! II! II! II! II! II!
24. Alterations of Cardiovascular Function II! II! II!
25. Alterations of Cardiovascular Function in Children II! II! II! II! II!
Unit 8: The Pulmonary System
II! II! II! II!
26. Structure and Function of the Pulmonary System II! II! II! II! II! II!
27. Alterations of Pulmonary Function II! II! II!
28. Alterations of Pulmonary Function in Children II! II! II! II! II!
Unit 9: The Renal and Urologic Systems
II! II! II! II! II! II!
29. Structure and Function of the Renal and Urologic Systems II! II! II! II! II! II! II! II!
30. Alterations of Renal and Urinary Tract Function II! II! II! II! II! II!
31. Alterations of Renal and Urinary Tract Function in Children II! II! II! II! II! II! II! II!
,Unit 10: The Reproductive Systems
II! II! II! II!
32. Structure and Function of the Reproductive Systems
II! II! II! II! II! II!
33. Alterations of the Female Reproductive System
II! II! II! II! II!
34. Alterations of the Male Reproductive System
II! II! II! II! II!
Unit 11: The Digestive System
II! II! II! II!
35. Structure and Function of the Digestive System
II! II! II! II! II! II!
36. Alterations of Digestive Function
II! II! II!
37. Alterations in Digestive Function in Children
II! II! II! II! II!
Unit 12: The Musculoskeletal and Integumentary Systems
II! II! II! II! II! II!
38. Structure and Function of the Musculoskeletal System
II! II! II! II! II! II!
39. Alterations of Musculoskeletal Function
II! II! II!
40. Alterations of Musculoskeletal Function in Children
II! II! II! II! II!
41. Structure, Function, and Disorders of the Integument
II! II! II! II! II! II!
42. Alterations of the Integument in Children
II! II! II! II! II!
, Chapter 01: Cellular Biology
II! II! II!
MULTIPLE CHOICE II!
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
II! II! II! II! II! II! II! II! II! II! II! II! II! II! II!
with histones. Which of the following would also be observed by the student?
II! II! II! II! II! II! II! II! II! II! II! II! II!
a. A single circular chromosome II! II! II!
b. A nucleus II!
c. Free-floating nuclear material II! II!
d. No organelles II!
ANS: B I I !
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
II! II! II! II! II! II! II! II! II! II! II! II! II! II! II! II!
nucleus; thus, the nucleus should be observed. A single circular chromosome called a
II! II! II! II! II! II! II! II! II! II! II! II! II!
prokaryote contains free-floating nuclear material but has no organelles.
II! II! II! II! II! II! II! II! II!
REF: I I ! p. 2 II!
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
II! II! II! II! II! II! II! II! II! II! II! II! II! II!
II! describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
II! II! II! II! II! II! II! II! II! II! II! II! II! II!
a. Metabolic absorption II!
b. Communication
c. Secretion
d. Respiration
ANS: I I ! D NURSINGTB.COM
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
II! II! II! II! II! II! II! II! II! II! II! II! II! II!
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
II! II! II! II! II! II! II! II! II! II! II!
secretion allows for the synthesizing of new substances.
II! II! II! II! II! II! II! II!
REF: I I ! p. 2 II!
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the
II! II! II! II! II! II! II! II! II! II! II! II! II! II! II! II!
genetic information be contained?
II! II! II! II!
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm II!
ANS: C I I !
The region of the cell that contains genetic material, including a large amount of ribonucleic acid,
II! II! II! II! II! II! II! II! II! II! II! II! II! II! II!
most of the DNA, and DNA-binding proteins, is the nucleolus, which is located within the cell’s
II! II! II! II! II! II! II! II! II! II! II! II! II! II! II! II!
nucleus. Mitochondria is associated with cellular respiration, while ribosomes are involved
II! II! II! II! II! II! II! II! II! II! II!
with protein manufacturing. Cytoplasm is a fluid filling that is a component of the cell.
II! II! II! II! II! II! II! II! II! II! II! II! II! II! II!
REF: I I ! p. 2 II!
NURSINGTB.COM