https://www.stuvia.com/
TEST BANK FOR MODERN BLOOD BANKING
m m m m m m
& TRANSFUSION PRACTICES 7TH EDITION B
m m m m m
Y DENISE M HARMENING
m m m
9780803668881 CHAPTER 1- m m
29 COMPLETE GUIDE
m m
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
m m m m m m m m m m
MultiplemChoice
Identifymthemchoicemthatmbestmcompletesmthemstatementmormanswersmthemquestion.
1. Whichmmetabolicmpathwaymismresponsiblemformgeneratingm90%mofmthemATPmformthemRBC?
a. Pentosemphosphatemshunt c. Glycolysis
b. Luebering-Rapoportmshunt d.m Methemoglobinmreductase
2. Amunitmofmbloodmwasmreturnedmtomthembloodmbankmbeforemitmwasmspiked.mApparentlymthempatient’smIVmfailed.
mThemunitmofmbloodmwasmoutsidemthembloodmbankmform35mminutes.mWhichmofmthemstatementsmbelowmismmost
maccurate?
a. Themunitmofmbloodmshouldmbemdiscardedmimmediately.
b. Themunitmofmbloodmcanmbemreturnedmtominventory.
c. Themunitmofmbloodmmustmbemtransfusedmwithinm4mhoursmormbemdiscardedmatmthemendmofmthatmtime.
d. Themunitmofmbloodmmustmbemtransfusedmwithm24mhours.
3. Whatmismthemaveragemdiametermofmamplatelet?
a. 5mtom10mµm c. 1mtom2mµm
b. 2mtom4mµm d.m m 4mtom6mµm
4. Inmthemnormalmhemoglobin-
oxygenmdissociationmcurve,mwhatmpercentagemofmoxygenmismreleasedmtomthemtissuesmwhenmPO2m averagesm
40mmmmHg?
a. 75% c. 100%
b. 25% d.m 50%
5. Whatmfactorsmaremknownmtominfluencemplateletmmetabolismmandmfunction?
a. Storagemtemperature c. Plateletmcount
b. InitialmpH d.m Allmofmthemabove
6. Whichmofmthemfollowingmredmbloodmcellmmorphologiesmmaymbempresentmonmthemperipheralmbloodmsmearmasmamr
esultmofmlossmofmRBCmmembrane?
a. Spherocytes c. Burrmcells
b. Targetmcells d.m Schistocytes
7. Whatmdoesmthemtermmautologousmtransfusionmrefermto?
a. Amparentmdonatingmbloodmformhismormhermchild
b. Anmindividualmdonatingmbloodmformamfriend
c. Anmindividualmdonatingmbloodmformamrelative
d. Anmindividualmdonatingmbloodmformhismormhermownmtransfusion
8. Whatmismthemprimarymfunctionmofmhemoglobin?
a. Ironmmetabolism c. Oxygenmtransport
b. Porphyrinmsynthesis d.m Signalmtransduction
9. Allmofmthemfollowingmareasmofmredmbloodmcellmbiologymaremcrucialmformnormalmerythrocytemsurvivalm except:
a. Cellularmmetabolism. c. SitemofmthemABOmantigenmattachment.
b. RBCmmembrane. d.m Hemoglobinmstructure.
Thismstudymsourcemwasmdownloadedmbym100000826342158mfrommCourseHero.commonm09-15-
2021m17:54:15mGMTm-05:00
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,https://www.stuvia.com/
m 10.m WhatmismthemcorrectmbiochemicalmcompositionmofmthemRBCmmembrane?
a. 52%mprotein,m40%mlipid,m8%mcarbohydrate
b. 40%mprotein,m8%mlipid,m52%mcarbohydrate
c. 8%mprotein,m52%mlipid,m40%mcarbohydrate
d. 8%mlipid,m40%mcarbohydrate,m52%mprotein
m 11.m Allmofmthemfollowingmbiochemicalmchangesmaremassociatedmwithmlossmofmredmbloodmcellmviabilitymuponmstorage
except:
a. DecreasedmpH. c. IncreasedmATPmlevel.
b. Lossmofmredmbloodmcellmfunction. d.m Decreasedmglucosemconsumption.
m 12.m Whichmredmbloodmcellmpreservativemhasmamstoragemtimemofm35mdays?
a. ACD c. AS-1
b. CPDA-1 d.m m CPD
m 13.m ThemRBCmmembranemismrelativelympermeablemtomallmofmthemfollowingmexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.m Water.
m 14.mWhatmpercentagemofmplateletsmismsequesteredminmthemspleenmasmfunctionalmreservemaftermbeingmreleasedmfro
mmthembonemmarrow?
a. 30% c. 10%
b. 50% d.m m 25%
m 15.m Whatmismthemmajormbiochemicalmconsiderationminmplateletmstorage?
a. Glucosemmetabolism c. Productionmofmcarbonmdioxide
b. Oxygenmsupply d.m RegulationmofmpH
m 16.mWhatmwouldmthemhemoglobin-
oxygenmdissociationmcurvemdepictminmampatientmexhibitingmclinicalmsignsmofmalkalosis?
a. Normal c. Shiftmtomthemright
b. Shiftmtomthemleft d.m Nonemofmthemabove
m 17.m Namemthemmainmlipidmcomponentsmofmamredmbloodmcellmmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.m GlycophorinmA
m 18.m ThemABOmbloodmgroupsmweremdiscoveredminm1901mbymwhom?
a. CharlesmDrew c. LoutitmandmMollison
b. KarlmLandsteiner d.m EdwardmLindeman
m 19.mAmstandingmordermofmplateletsmwasmshippedmtomyourmfacilitymbymyourmsupplier.mItmwasminadvertentlymleftminmt
hemcornermofmthemdepartmentmuntilmdiscoveredm36mhoursmlater.mWhatmwouldmthemappropriatemactionmbemformth
embloodmbanker?
a. Ifmthemtemperatureminmthemboxmwasm22m+/-
m2°CmandmthemplateletmswirlmseemedmOK,mitmwouldmbemOKmtomacceptmthemunitmintominvento
ry.
b. Themplateletsmhavemfallenmoutsidemthemsupplier’smqualitymassurance.mThemunitmshouldmbe
mdiscardedmbecausemthempHmhasmprobablymdroppedmtoomlowmandmplateletmactivationmhasm
beenmcompromised.
c. Ifmthemtemperaturemwasm1°Cmtom6°CmandmthemplateletmswirlmseemedmOK,mitmwouldmbemOKmto
Thismstudymsourcemwasmdownloadedmbym100000826342158mfrommCourseHero.commonm09-15-
2021m17:54:15mGMTm-05:00
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,https://www.stuvia.com/
acceptmthemunitmintominventory.
d. IfmthemplateletsmappearedmOKmandmpassedmthemplateletmswirlmtestmaftermbeingmplacedmon
mthemagitator,mtheymcouldmbemacceptedmintomtheminventory.
m 20.m Whichmmetabolicmpathwaympermitsmthemaccumulationmofm2,3mdiphosphoglyceratem(2,3-DPG)?
a. Glycolysis c. Pentosemphosphatemshunt
b. Luebering-Rapoportmshunt d.m Methemoglobinmreductase
m 21.m Allmofmthemfollowingmaremconsistentmwithmam"shiftmtomthemright"mofmthemhemoglobin-oxygenmdissociationmcurve
except:
a. Increasedm2,3-DPG.
b. 50%mO2m saturationmtomtissues.
c. Decreasedm2,3-DPG.
d. DecreasedmhemoglobinmaffinitymformO2.
m 22.m Whatmismthemnormalmplateletmcountmrangempermcubicmmillimeter?
a. 100mtom350 c. 50,000mtom200,000
b. 150,000mtom350,000 d.m 350,000mtom500,000
m 23.m Whatmcryoprotectivemagentmismaddedmtomredmbloodmcellsmuponmfreezing?
a. Dextrose c. Glycerol
b. Adsol d.m Allmofmthemabove
m 24.m Ifmplateletsmaremtombemstoredmform5mdaysmonmamrotator,mwhatmismthemoptimalmstoragemtemperature?
a. 1°Cmtom6°C c. 35°Cmtom37°C
b. 20°Cmtom24°C d.m 1°Cmtom10°C
m 25.m Whatmrolemdomplateletsmplayminmhemostasis?
a. Maintenancemofmvascularmintegrity
b. Initialmarrestmofmbleedingmbymplateletmplugmformation
c. Stabilizationmofmthemhemostaticmplug
d. Allmofmthemabove
m 26.m Whichmofmthemfollowingmbestmdescribesm"integral"mmembranemproteins?
a. Residematmthemcytoplasmicmsurfacemofmmembrane
b. Spanmthementiremmembranemsurface
c. Formmthemredmbloodmcellmcytoskeleton
d. Nonemofmthemabove
m 27.m Howmismstroma-freemhemoglobinmsolutionmprepared?
a. Outdatedmredmbloodmcellsmaremconcentrated,mandmstromamismremoved.
b. Outdatedmredmbloodmcellsmaremdilutedmwithmsaline,mandmstromamismremoved.
c. Outdatedmredmbloodmcellsmaremlysed,mandmstromamismremoved.
d. Nonemofmthemabove
m 28.m WhatmismthemnormalmlifemspanmofmanmRBC?
a. 100mdays c. 120mhours
b. 120mdays d.m 2mdays
m 29.m RegardingmlossmofmRBCmmembranemdeformability,mallmofmthemfollowingmaremtruemexcept:
a. IncreaseminmATPmlevel.
b. DecreaseminmATPmlevel.
Thismstudymsourcemwasmdownloadedmbym100000826342158mfrommCourseHero.commonm09-15-
2021m17:54:15mGMTm-05:00
https://www.coursehero.com/file/25537437/ch01rtf/
TEST BANK FOR MODERN BLOOD BANKING
m m m m m m
& TRANSFUSION PRACTICES 7TH EDITION B
m m m m m
Y DENISE M HARMENING
m m m
9780803668881 CHAPTER 1- m m
29 COMPLETE GUIDE
m m
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
m m m m m m m m m m
MultiplemChoice
Identifymthemchoicemthatmbestmcompletesmthemstatementmormanswersmthemquestion.
1. Whichmmetabolicmpathwaymismresponsiblemformgeneratingm90%mofmthemATPmformthemRBC?
a. Pentosemphosphatemshunt c. Glycolysis
b. Luebering-Rapoportmshunt d.m Methemoglobinmreductase
2. Amunitmofmbloodmwasmreturnedmtomthembloodmbankmbeforemitmwasmspiked.mApparentlymthempatient’smIVmfailed.
mThemunitmofmbloodmwasmoutsidemthembloodmbankmform35mminutes.mWhichmofmthemstatementsmbelowmismmost
maccurate?
a. Themunitmofmbloodmshouldmbemdiscardedmimmediately.
b. Themunitmofmbloodmcanmbemreturnedmtominventory.
c. Themunitmofmbloodmmustmbemtransfusedmwithinm4mhoursmormbemdiscardedmatmthemendmofmthatmtime.
d. Themunitmofmbloodmmustmbemtransfusedmwithm24mhours.
3. Whatmismthemaveragemdiametermofmamplatelet?
a. 5mtom10mµm c. 1mtom2mµm
b. 2mtom4mµm d.m m 4mtom6mµm
4. Inmthemnormalmhemoglobin-
oxygenmdissociationmcurve,mwhatmpercentagemofmoxygenmismreleasedmtomthemtissuesmwhenmPO2m averagesm
40mmmmHg?
a. 75% c. 100%
b. 25% d.m 50%
5. Whatmfactorsmaremknownmtominfluencemplateletmmetabolismmandmfunction?
a. Storagemtemperature c. Plateletmcount
b. InitialmpH d.m Allmofmthemabove
6. Whichmofmthemfollowingmredmbloodmcellmmorphologiesmmaymbempresentmonmthemperipheralmbloodmsmearmasmamr
esultmofmlossmofmRBCmmembrane?
a. Spherocytes c. Burrmcells
b. Targetmcells d.m Schistocytes
7. Whatmdoesmthemtermmautologousmtransfusionmrefermto?
a. Amparentmdonatingmbloodmformhismormhermchild
b. Anmindividualmdonatingmbloodmformamfriend
c. Anmindividualmdonatingmbloodmformamrelative
d. Anmindividualmdonatingmbloodmformhismormhermownmtransfusion
8. Whatmismthemprimarymfunctionmofmhemoglobin?
a. Ironmmetabolism c. Oxygenmtransport
b. Porphyrinmsynthesis d.m Signalmtransduction
9. Allmofmthemfollowingmareasmofmredmbloodmcellmbiologymaremcrucialmformnormalmerythrocytemsurvivalm except:
a. Cellularmmetabolism. c. SitemofmthemABOmantigenmattachment.
b. RBCmmembrane. d.m Hemoglobinmstructure.
Thismstudymsourcemwasmdownloadedmbym100000826342158mfrommCourseHero.commonm09-15-
2021m17:54:15mGMTm-05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
m 10.m WhatmismthemcorrectmbiochemicalmcompositionmofmthemRBCmmembrane?
a. 52%mprotein,m40%mlipid,m8%mcarbohydrate
b. 40%mprotein,m8%mlipid,m52%mcarbohydrate
c. 8%mprotein,m52%mlipid,m40%mcarbohydrate
d. 8%mlipid,m40%mcarbohydrate,m52%mprotein
m 11.m Allmofmthemfollowingmbiochemicalmchangesmaremassociatedmwithmlossmofmredmbloodmcellmviabilitymuponmstorage
except:
a. DecreasedmpH. c. IncreasedmATPmlevel.
b. Lossmofmredmbloodmcellmfunction. d.m Decreasedmglucosemconsumption.
m 12.m Whichmredmbloodmcellmpreservativemhasmamstoragemtimemofm35mdays?
a. ACD c. AS-1
b. CPDA-1 d.m m CPD
m 13.m ThemRBCmmembranemismrelativelympermeablemtomallmofmthemfollowingmexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.m Water.
m 14.mWhatmpercentagemofmplateletsmismsequesteredminmthemspleenmasmfunctionalmreservemaftermbeingmreleasedmfro
mmthembonemmarrow?
a. 30% c. 10%
b. 50% d.m m 25%
m 15.m Whatmismthemmajormbiochemicalmconsiderationminmplateletmstorage?
a. Glucosemmetabolism c. Productionmofmcarbonmdioxide
b. Oxygenmsupply d.m RegulationmofmpH
m 16.mWhatmwouldmthemhemoglobin-
oxygenmdissociationmcurvemdepictminmampatientmexhibitingmclinicalmsignsmofmalkalosis?
a. Normal c. Shiftmtomthemright
b. Shiftmtomthemleft d.m Nonemofmthemabove
m 17.m Namemthemmainmlipidmcomponentsmofmamredmbloodmcellmmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.m GlycophorinmA
m 18.m ThemABOmbloodmgroupsmweremdiscoveredminm1901mbymwhom?
a. CharlesmDrew c. LoutitmandmMollison
b. KarlmLandsteiner d.m EdwardmLindeman
m 19.mAmstandingmordermofmplateletsmwasmshippedmtomyourmfacilitymbymyourmsupplier.mItmwasminadvertentlymleftminmt
hemcornermofmthemdepartmentmuntilmdiscoveredm36mhoursmlater.mWhatmwouldmthemappropriatemactionmbemformth
embloodmbanker?
a. Ifmthemtemperatureminmthemboxmwasm22m+/-
m2°CmandmthemplateletmswirlmseemedmOK,mitmwouldmbemOKmtomacceptmthemunitmintominvento
ry.
b. Themplateletsmhavemfallenmoutsidemthemsupplier’smqualitymassurance.mThemunitmshouldmbe
mdiscardedmbecausemthempHmhasmprobablymdroppedmtoomlowmandmplateletmactivationmhasm
beenmcompromised.
c. Ifmthemtemperaturemwasm1°Cmtom6°CmandmthemplateletmswirlmseemedmOK,mitmwouldmbemOKmto
Thismstudymsourcemwasmdownloadedmbym100000826342158mfrommCourseHero.commonm09-15-
2021m17:54:15mGMTm-05:00
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,https://www.stuvia.com/
acceptmthemunitmintominventory.
d. IfmthemplateletsmappearedmOKmandmpassedmthemplateletmswirlmtestmaftermbeingmplacedmon
mthemagitator,mtheymcouldmbemacceptedmintomtheminventory.
m 20.m Whichmmetabolicmpathwaympermitsmthemaccumulationmofm2,3mdiphosphoglyceratem(2,3-DPG)?
a. Glycolysis c. Pentosemphosphatemshunt
b. Luebering-Rapoportmshunt d.m Methemoglobinmreductase
m 21.m Allmofmthemfollowingmaremconsistentmwithmam"shiftmtomthemright"mofmthemhemoglobin-oxygenmdissociationmcurve
except:
a. Increasedm2,3-DPG.
b. 50%mO2m saturationmtomtissues.
c. Decreasedm2,3-DPG.
d. DecreasedmhemoglobinmaffinitymformO2.
m 22.m Whatmismthemnormalmplateletmcountmrangempermcubicmmillimeter?
a. 100mtom350 c. 50,000mtom200,000
b. 150,000mtom350,000 d.m 350,000mtom500,000
m 23.m Whatmcryoprotectivemagentmismaddedmtomredmbloodmcellsmuponmfreezing?
a. Dextrose c. Glycerol
b. Adsol d.m Allmofmthemabove
m 24.m Ifmplateletsmaremtombemstoredmform5mdaysmonmamrotator,mwhatmismthemoptimalmstoragemtemperature?
a. 1°Cmtom6°C c. 35°Cmtom37°C
b. 20°Cmtom24°C d.m 1°Cmtom10°C
m 25.m Whatmrolemdomplateletsmplayminmhemostasis?
a. Maintenancemofmvascularmintegrity
b. Initialmarrestmofmbleedingmbymplateletmplugmformation
c. Stabilizationmofmthemhemostaticmplug
d. Allmofmthemabove
m 26.m Whichmofmthemfollowingmbestmdescribesm"integral"mmembranemproteins?
a. Residematmthemcytoplasmicmsurfacemofmmembrane
b. Spanmthementiremmembranemsurface
c. Formmthemredmbloodmcellmcytoskeleton
d. Nonemofmthemabove
m 27.m Howmismstroma-freemhemoglobinmsolutionmprepared?
a. Outdatedmredmbloodmcellsmaremconcentrated,mandmstromamismremoved.
b. Outdatedmredmbloodmcellsmaremdilutedmwithmsaline,mandmstromamismremoved.
c. Outdatedmredmbloodmcellsmaremlysed,mandmstromamismremoved.
d. Nonemofmthemabove
m 28.m WhatmismthemnormalmlifemspanmofmanmRBC?
a. 100mdays c. 120mhours
b. 120mdays d.m 2mdays
m 29.m RegardingmlossmofmRBCmmembranemdeformability,mallmofmthemfollowingmaremtruemexcept:
a. IncreaseminmATPmlevel.
b. DecreaseminmATPmlevel.
Thismstudymsourcemwasmdownloadedmbym100000826342158mfrommCourseHero.commonm09-15-
2021m17:54:15mGMTm-05:00
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