Hypersensitivity is best defined as a(an) correct answers c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: correct answers
Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins? correct answers IgE
Which type of antibody is involved in type I hypersensitivity reaction? correct answers IgE
Blood transfusion reactions are an example of: correct answers Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? correct answers
c.
Eosinophils
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a result of
which receptor action? correct answers Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed to
develop allergies? correct answers c.
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions? correct answers d.
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the erythrocytes are
destroyed by correct answers a.
Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood cells are
destroyed by: correct answers Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a result of:
correct answers d.
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction? correct answers d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity reaction?
correct answers Modulation
,Type III hypersensitivity reactions are a result of which of the following? correct answers b.
Antibodies binding to soluble antigens that were released into body fluids and the immune
complexes being deposited in the tissues
A type IV hypersensitivity reaction causes which result? correct answers .
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes that are
deposited in tissues are a result of: correct answers Complement activation
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to: correct
answers a.
Immune complexes that are deposited in capillary beds, blocking circulation
Deficiencies in which element can produce depression of both B- and T-cell function? correct
answers Zinc
When the maternal immune system becomes sensitized against antigens expressed by the fetus,
what reaction occurs? correct answers Alloimmunity
Tissue damage caused by the deposition of circulating immune complexes containing an
antibody against the host DNA is the cause of which disease? correct answers Systemic lupus
erythematosus
Why does tissue damage occurs in acute rejection after organ transplantation? correct answers a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly
attack the endothelial cells of the transplanted tissue.
Which blood cell carries the carbohydrate antigens for blood type? correct answers Erythrocytes
A person with type O blood is likely to have high titers of which anti-antibodies? correct answers
A and B
Which class of immunoglobulins forms isohemagglutinins? correct answers IgM
Which component of the immune system is deficient in individuals with infections caused by
viruses, fungi, or yeast? correct answers T cells
In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity?
correct answers DiGeorge syndrome
How many months does it take for the newborn to be sufficiently protected by antibodies
produced by its own B cells? correct answers 6 to 8
, Considering the effects of nutritional deficiencies on the immune system, severe deficits in
calories and protein lead to deficiencies in the formation of which immune cells? correct answers
T cells
Urticaria are a manifestation of a which type of hypersensitivity reaction? correct answers Type I
Graves disease is a result of: correct answers c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites
Raynaud phenomenon is an example of which type of hypersensitivity? correct answers Type III
Which statement is true concerning an atopic individual? correct answers They tend to produce
more Fc receptors.
Which statement is true regarding immunodeficiency? correct answers a.
Immunodeficiency is generally not present in other family members
A person with type O blood is considered to be the universal blood donor because type O blood
contains which of the following? correct answers No antigens
Immunoglobulin E (IgE) is associated with which type of hypersensitivity reaction? correct
answers Type I
Graves disease is an autoimmune disease that results in which maternal antibody? correct
answers b.
Affecting the receptor for TSH, causing neonatal hyperthyroidism
When a tuberculin skin test is positive, the hard center and erythema surrounding the induration
are a result of which of the following? (Select all that apply.) correct answers T lymphocytes and
Macrophages
Exposure to which of the following could result in a type IV hypersensitivity reaction? (Select all
that apply.) correct answers Poison Ivy, Neomycin, Nickel, Detergents
Which disorders are considered autoimmune? (Select all that apply correct answers Crohns,
Addisons, Rheumatoid arthritis, systemic lupus erythematosus
Which statements best define acute rejection? (Select all that apply.) correct answers c.
Immunosuppressive drugs delay or lessen the intensity of an acute rejection.
d.
Acute rejection is associated with the body's response to an organ transplant.
e.
Acute rejection is a response against unmatched human leukocyte antigens (HLAs
a. Acute rejection is a cell-mediated immune response
Which action is a purpose of the inflammatory process? correct answers c.