Bio 272 exam 4 questions and answers
G1 phase - Correct Answers -cells grow and increase the mass of proteins and
organelles
S phase - Correct Answers -DNA replication, centrosome duplication
G2 phase - Correct Answers -DNA exists as chromatids, centrosome separation begins
M phase - Correct Answers -mitosis
Order of Mitosis Phases - Correct Answers -prophase, prometaphase, metaphase,
anaphase, telophase, cytokinesi Mcdk phosphorylates __, which triggers disassembly of
nuclear lamina - Correct Answers -nuclear lamins
Mcdk phosphorylates __, promoting their disassembly - Correct Answers -nuclear pore
complexes
kinetochore is built upon - Correct Answers -centromere DNA region of each
chromosome
plus ends of kinetochore MTs are embedded in __ - Correct Answers -MT attachment
sites
each duplicated chromosome has __ kinetochores - Correct Answers -2
prophase - Correct Answers -centrosome migration, mitotic spindle begins to form,
chromosomes begin to condense and appear as long threads
Prometaphase - Correct Answers -nuclear envelope breaks down, chromosome
condensation completes, chromosomes attach to spindle MTs via their kinetochores
metaphase - Correct Answers -chromosomes align at the equitorial plane of the bipolar
spindle
Anaphase - Correct Answers -chromosome separation, kinetochore MTs shorten and
spindle poles move apart
telophase - Correct Answers -chromosomes decondense, nuclear envelope reforms,
spindles disassemble
, cytokinesis initiation happens during __ - Correct Answers -anaphase
cytokinesis - Correct Answers -cytoplasmic division by the actomyosin contractile ring,
interphase MT array re-forms
during flow cytometry, cells are stained with __ - Correct Answers -DNA dye
G1/S checkpoint checks for - Correct Answers -sufficient nutrients, signal molecules
present
G2/M checkpoint checks for - Correct Answers -all DNA replicated, DNA damage
repaired
M checkpoint checks for - Correct Answers -chromosome attachment to spindle
cyclin-dependent kinase - Correct Answers -key regulators of the cell cycle control
system
CDKs are __ kinases - Correct Answers -serine/threonine
CDKs form complexes with - Correct Answers -cyclins
(with/without) cyclin, CDK is active - Correct Answers -with
(with/without) cyclin, CDK is inactive - Correct Answers -without
active Cdk triggers __ by __ - Correct Answers -cell-cycle events; phosphorylating
target proteins to initiate them
of the CDK complex, cyclins are the __ subunit - Correct Answers -regulatory
of the CDK complex, Cdks are the __ subunit - Correct Answers -catalytic
every cyclin-Cdk complex phosphorylates __ target proteins - Correct Answers -different
M-Cdk (a.k.a. MPF) = __ - Correct Answers -cyclin B/Cdk1
__ undergo a cycle of synthesis and degradation in each cell cycle. - Correct Answers -
cyclins
__ protein concentration cycles - increases throughout interphase and early mitosis,
then drops abruptly partway through mitosis. - Correct Answers -M-cyclin (cyclin B)
Cdk1 protein concentration is __ throughout the cell cycle - Correct Answers -constant
G1 phase - Correct Answers -cells grow and increase the mass of proteins and
organelles
S phase - Correct Answers -DNA replication, centrosome duplication
G2 phase - Correct Answers -DNA exists as chromatids, centrosome separation begins
M phase - Correct Answers -mitosis
Order of Mitosis Phases - Correct Answers -prophase, prometaphase, metaphase,
anaphase, telophase, cytokinesi Mcdk phosphorylates __, which triggers disassembly of
nuclear lamina - Correct Answers -nuclear lamins
Mcdk phosphorylates __, promoting their disassembly - Correct Answers -nuclear pore
complexes
kinetochore is built upon - Correct Answers -centromere DNA region of each
chromosome
plus ends of kinetochore MTs are embedded in __ - Correct Answers -MT attachment
sites
each duplicated chromosome has __ kinetochores - Correct Answers -2
prophase - Correct Answers -centrosome migration, mitotic spindle begins to form,
chromosomes begin to condense and appear as long threads
Prometaphase - Correct Answers -nuclear envelope breaks down, chromosome
condensation completes, chromosomes attach to spindle MTs via their kinetochores
metaphase - Correct Answers -chromosomes align at the equitorial plane of the bipolar
spindle
Anaphase - Correct Answers -chromosome separation, kinetochore MTs shorten and
spindle poles move apart
telophase - Correct Answers -chromosomes decondense, nuclear envelope reforms,
spindles disassemble
, cytokinesis initiation happens during __ - Correct Answers -anaphase
cytokinesis - Correct Answers -cytoplasmic division by the actomyosin contractile ring,
interphase MT array re-forms
during flow cytometry, cells are stained with __ - Correct Answers -DNA dye
G1/S checkpoint checks for - Correct Answers -sufficient nutrients, signal molecules
present
G2/M checkpoint checks for - Correct Answers -all DNA replicated, DNA damage
repaired
M checkpoint checks for - Correct Answers -chromosome attachment to spindle
cyclin-dependent kinase - Correct Answers -key regulators of the cell cycle control
system
CDKs are __ kinases - Correct Answers -serine/threonine
CDKs form complexes with - Correct Answers -cyclins
(with/without) cyclin, CDK is active - Correct Answers -with
(with/without) cyclin, CDK is inactive - Correct Answers -without
active Cdk triggers __ by __ - Correct Answers -cell-cycle events; phosphorylating
target proteins to initiate them
of the CDK complex, cyclins are the __ subunit - Correct Answers -regulatory
of the CDK complex, Cdks are the __ subunit - Correct Answers -catalytic
every cyclin-Cdk complex phosphorylates __ target proteins - Correct Answers -different
M-Cdk (a.k.a. MPF) = __ - Correct Answers -cyclin B/Cdk1
__ undergo a cycle of synthesis and degradation in each cell cycle. - Correct Answers -
cyclins
__ protein concentration cycles - increases throughout interphase and early mitosis,
then drops abruptly partway through mitosis. - Correct Answers -M-cyclin (cyclin B)
Cdk1 protein concentration is __ throughout the cell cycle - Correct Answers -constant
