ONS ONCC CHEMO FINAL PAPER 2025/2026 QUESTIONS
AND ANSWERS GUARANTEE A+
✔✔Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin - ✔✔DNA Binding Irritants
✔✔Amsacrine
Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine - ✔✔DNA Nonbinding vessicants
✔✔Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures. - ✔✔Extravasciation Alkylating / Mechlorethamine tx
✔✔Apply warm compresses.
Dexamethasone
8 mg twice daily
for 14 days - ✔✔Extravasciation Alkylating: Oxaliplatin
✔✔Totect
Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of extravasation.
Infused over 1-2 hours for three days in an area other
than the extravasation site
The dose recommended is based on the patients' body
surface area.
• Day 1: 1,000 mg/m2
, • Day 2: 1,000 mg/m2
• Day 3: 500 mg/m - ✔✔Extravasation Tx: Anthracyclines --- Daunorubicin,
doxorubicin, epirubicin,
idarubicin
✔✔Hyaluronidase
Apply warm pack for
15-20 minutes four times
daily the next 24-48
hours and keep extremity
elevated.
Administer 1 ml of hyaluronidase subcutaneously in five
separate injections, each containing 0.2 ml of the solution
using a 25 gauge or smaller needle. - ✔✔Extravasation Tx: Plant alkaloid Vinblastine,
vincristine,
vindesine,
vinorelbine
✔✔Apply ice pack for 15-20
minutes four times daily
the first 24 hours.
No known antidote - ✔✔Extravascation Tx: Taxanes Docetaxel, paclitaxe
✔✔include aching and tightness along a peripheral vein above the administration site
that occurs as the drug infuses, as well as potential redness or darkening of the vein
without swelling and ulceration. Blood return is typically present; if not, an infiltration
may have occurred - ✔✔Signs of symptoms of venous irritation:
✔✔warm compress - ✔✔Most sources recommend the application of heat using
_______________ to help reduce local discomfort and the restart of the peripheral IV in
a larger vein (Polovich et al., 2014).
✔✔irinotecan - ✔✔The manufacturer of ______________ recommends topical flushing
of the skin with sterile water and application of ice in the event of extravasation of the
drug (Pfizer Inc., 2012).
✔✔Burning, stinging pain around the administration site, although it is important to note
that some patients do not experience any pain with vesicant extravasation and may in
fact experience a feeling of coolness at the site (Polovich et al., 2014). -
✔✔Extravasation signs and symptoms can include
✔✔Constipation is not a likely side effect with the agents that Mrs. Turner is to receive.
Actually diarrhea is more likely when receiving both of the targeted therapies in this
AND ANSWERS GUARANTEE A+
✔✔Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin - ✔✔DNA Binding Irritants
✔✔Amsacrine
Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine - ✔✔DNA Nonbinding vessicants
✔✔Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures. - ✔✔Extravasciation Alkylating / Mechlorethamine tx
✔✔Apply warm compresses.
Dexamethasone
8 mg twice daily
for 14 days - ✔✔Extravasciation Alkylating: Oxaliplatin
✔✔Totect
Apply ice pack (remove 15
minutes prior to Totect
treatment).
Infusion should be initiated within six hours of extravasation.
Infused over 1-2 hours for three days in an area other
than the extravasation site
The dose recommended is based on the patients' body
surface area.
• Day 1: 1,000 mg/m2
, • Day 2: 1,000 mg/m2
• Day 3: 500 mg/m - ✔✔Extravasation Tx: Anthracyclines --- Daunorubicin,
doxorubicin, epirubicin,
idarubicin
✔✔Hyaluronidase
Apply warm pack for
15-20 minutes four times
daily the next 24-48
hours and keep extremity
elevated.
Administer 1 ml of hyaluronidase subcutaneously in five
separate injections, each containing 0.2 ml of the solution
using a 25 gauge or smaller needle. - ✔✔Extravasation Tx: Plant alkaloid Vinblastine,
vincristine,
vindesine,
vinorelbine
✔✔Apply ice pack for 15-20
minutes four times daily
the first 24 hours.
No known antidote - ✔✔Extravascation Tx: Taxanes Docetaxel, paclitaxe
✔✔include aching and tightness along a peripheral vein above the administration site
that occurs as the drug infuses, as well as potential redness or darkening of the vein
without swelling and ulceration. Blood return is typically present; if not, an infiltration
may have occurred - ✔✔Signs of symptoms of venous irritation:
✔✔warm compress - ✔✔Most sources recommend the application of heat using
_______________ to help reduce local discomfort and the restart of the peripheral IV in
a larger vein (Polovich et al., 2014).
✔✔irinotecan - ✔✔The manufacturer of ______________ recommends topical flushing
of the skin with sterile water and application of ice in the event of extravasation of the
drug (Pfizer Inc., 2012).
✔✔Burning, stinging pain around the administration site, although it is important to note
that some patients do not experience any pain with vesicant extravasation and may in
fact experience a feeling of coolness at the site (Polovich et al., 2014). -
✔✔Extravasation signs and symptoms can include
✔✔Constipation is not a likely side effect with the agents that Mrs. Turner is to receive.
Actually diarrhea is more likely when receiving both of the targeted therapies in this
