BIO CHEMISTRY EXAM 2025 QUESTIONS AND
ANSWERS GRADED A+
Which of the following elevates carboxyhemoglobin?
a. nitrite poisoning
b. exposure to carbon monoxide
c. sulfa drug toxicity
d. sickle cell anemia
b
The reason carbon monoxide is so toxic is because it:
a. is a protoplasmic poison
b. comibines with cytochrome oxidase
c. has 200 times the affinity of oxygen for hemoglobin binding sites
d. sensitizes the myocardium
c
Cocain is metabolized to:
a. carbamazepinne
b. codeine
c. hydrocodone
d. benzoylecgonine
,d
The metabolite 11-nor-etrahydrocannabinol-9-COOH- can be detected by immunoassay 3-5 days
after a single use of:
a. methamphetamine
b. cocaine
c. benzodiazepine
d. marijuana
d
A 3 year old child was evaluated for abdominal pain and anorexia by a physician. A CBC
revealed a hemoglobin of 9.8 g/dL and basophilic stippling of the RBCs. The doctor should order
further tests to check for poisoning from:
a. arsenic
b. iron
c. mercury
d. lead
d
Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood
concentration of:
a. lead
b. mercury
c. arsenic
,d. beryllium
a
A salicylate level is performed to detect toxicity caused by ingestion of excess:
a. acetominophen
b. aspirin
c. ibuprofen
d. pseudoephedrine
b
Testing for the diagnosis of lead poisoning should include:
a. erythrocyte protoporphyrin (EPP)
b. urine delta-aminolevulinic acid
c. whole blood lead
d. zinc protoporphryin (ZPP)
c
Upon development of a thin layer chromatogram for the drug analysis, all drug spots (including
the standards) had migrated with the solvent front. The most probable cause for this would be:
a. environmental temperature too warm
b. incorrect aqueous to non aqueous solvent mixture
, c. too much sample applied
d. chromatogram dried too quickly
b
To detect barbiturate abuse when analyzing urine specimens, immunoassay is the method of
choice for screening. The method of choice for confirmation is:
a. nephelometry
b. thin-layer chromatography
c. gas chromatography/mass spec
d. ultraviolet absorption spectroscopy
c
Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
a. <70 mg/dL
b. <60 mg/dL
c. <55 mg/dL
d. <45 mg/dL
c
The preparation of a patient for standard glucose tolerance testing should include:
a. a high carbohydrate diet for 3 days
b. a low carbohydrate diet for 3 days
ANSWERS GRADED A+
Which of the following elevates carboxyhemoglobin?
a. nitrite poisoning
b. exposure to carbon monoxide
c. sulfa drug toxicity
d. sickle cell anemia
b
The reason carbon monoxide is so toxic is because it:
a. is a protoplasmic poison
b. comibines with cytochrome oxidase
c. has 200 times the affinity of oxygen for hemoglobin binding sites
d. sensitizes the myocardium
c
Cocain is metabolized to:
a. carbamazepinne
b. codeine
c. hydrocodone
d. benzoylecgonine
,d
The metabolite 11-nor-etrahydrocannabinol-9-COOH- can be detected by immunoassay 3-5 days
after a single use of:
a. methamphetamine
b. cocaine
c. benzodiazepine
d. marijuana
d
A 3 year old child was evaluated for abdominal pain and anorexia by a physician. A CBC
revealed a hemoglobin of 9.8 g/dL and basophilic stippling of the RBCs. The doctor should order
further tests to check for poisoning from:
a. arsenic
b. iron
c. mercury
d. lead
d
Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood
concentration of:
a. lead
b. mercury
c. arsenic
,d. beryllium
a
A salicylate level is performed to detect toxicity caused by ingestion of excess:
a. acetominophen
b. aspirin
c. ibuprofen
d. pseudoephedrine
b
Testing for the diagnosis of lead poisoning should include:
a. erythrocyte protoporphyrin (EPP)
b. urine delta-aminolevulinic acid
c. whole blood lead
d. zinc protoporphryin (ZPP)
c
Upon development of a thin layer chromatogram for the drug analysis, all drug spots (including
the standards) had migrated with the solvent front. The most probable cause for this would be:
a. environmental temperature too warm
b. incorrect aqueous to non aqueous solvent mixture
, c. too much sample applied
d. chromatogram dried too quickly
b
To detect barbiturate abuse when analyzing urine specimens, immunoassay is the method of
choice for screening. The method of choice for confirmation is:
a. nephelometry
b. thin-layer chromatography
c. gas chromatography/mass spec
d. ultraviolet absorption spectroscopy
c
Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
a. <70 mg/dL
b. <60 mg/dL
c. <55 mg/dL
d. <45 mg/dL
c
The preparation of a patient for standard glucose tolerance testing should include:
a. a high carbohydrate diet for 3 days
b. a low carbohydrate diet for 3 days
