Regis NU641 Adv Pharmacology Exam Questions
With Correct Answers 2025 Marking Scheme New
Update
hyperlipidemia - Answer-high cholesterol levels in the blood, which can lead to heart dz,
stroke and other problems caused by block arteries
/.Atherosclerosis - Answer-Changes in the walls of large arteries consisting of lipid
deposits on the artery walls, which incidences can be reduced with proper treatment of
hyperlipidemia
/.Treatment goal of hyperlipidemia - Answer-lowering of the cholesterol to appropriate
levels to decrease the risk of heart attack and stroke
/.Non-pharmacology treatment - Answer-Therapeutic Lifestyle Changes (TLC) important
part of treatment and are not futile
/.Pharmacology - Answer-Medications
/.Statins - Answer-lower cholesterol in the blood and reduce its production in the liver by
blocking the enzyme that produces it; has adverse effects that can occur more
frequently at higher doses.
/.LDL cholesterol - Answer-goal of < 70 in high risk patients
goal of < 100 in mod high-risk patients
/.DM pts w/ acute coronary artery syndrome & multiple or uncontrolled risk factors; Tx =
- Answer-TLC, changes in diet restrict refined carbs (sugar & liquid calories), wgt loss
(pt will not be able to participate in aerobic activity if had previous MI), decreased insulin
resistance, decreased BP, improved cardiovascular conditioning, limit/ restrict ETOH
consumption.
/.Which patients are easier to manage? - Answer-Patients at low risk for developing
heart dz.
/.What med is recommended if the LDL cannot be decreased by a high dose of potent
statin? - Answer-Nicotinic acid
/.Med combination to lower triglycerides and increase the HDL - Answer-a
fibrate/nicotinic acid with statin
, /.Patient Education for Statin - Answer-Pt to report report extreme fatigue, darked-color
urine, ck elevated, rhabdomylitis (muscle aches); if reported stop immediately and
check LFT(Liver Fxn Test)
/.lescol (Statin) - Answer-This med can affect liver function and increase liver enzymes
as well cause the pt to feel weak, fatigue and have muscle aches checking the LFT is
recommended
/.Acute drug induced hepatitis - Answer-the Liver enzymes are elevated w/ the use of
statin
/.If pt has acute and chronic hepatitis, liver disease cirrhosis and alcoholism; or
pregnant/breastfeeding mothers - Answer-DO NOT PRESCRIBE STATINS
/.First-line therapy for hyperlipidemia - Answer-Therapeutic Life Changes (TLC) Such
as: balanced diet, weight loss, minimize risk factors before medications
/.Which drug class is most effective for the management of hyperlipidemia with
concurrent elevated triglycerides (TGs)? - Answer-Fibrates
/.How do you identify the potential serious adverse drug reactions with hyperlipidemia
agents? - Answer-Monitor BP within 1 to 3 hours of administration to check for
hypotensive affect
/.What type of counseling would you give to a pt who just started on hyperlipidemia
agents, such as an HMG Co-A reductase inhibitor (statin), etc? - Answer-myopathy and
hepatatoxicity
/.What is the second line treatment options if a patient fails a statin? - Answer-Bile acid-
binding resins
/.Patient factors which preclude use of an HMG Co-A reductase inhibitor - Answer-
*patients with active hepatic disease or unexplained persistent elevations in
aminotransferase levels
* in pregnancy and during breastfeeding as cholesterol is an essential component for
fetal and infant synthesis of steroids and cell membrane development
*caution is necessary for patients with already increased blood glucose *levels or
increased Hba1c levels.
can increase the risk of statin-induced myopathy
/.Which hyperlipidemia agents are appropriate for use in pregnancy with respect to risk
to fetus as well as mother? - Answer-Fibrates
/.Which drug (statin) decrease LDL at a greatest percentage? - Answer-Rosuvastatin
/.Post MI dose of ASA - Answer-BMI > 29 = 325mg ASA
With Correct Answers 2025 Marking Scheme New
Update
hyperlipidemia - Answer-high cholesterol levels in the blood, which can lead to heart dz,
stroke and other problems caused by block arteries
/.Atherosclerosis - Answer-Changes in the walls of large arteries consisting of lipid
deposits on the artery walls, which incidences can be reduced with proper treatment of
hyperlipidemia
/.Treatment goal of hyperlipidemia - Answer-lowering of the cholesterol to appropriate
levels to decrease the risk of heart attack and stroke
/.Non-pharmacology treatment - Answer-Therapeutic Lifestyle Changes (TLC) important
part of treatment and are not futile
/.Pharmacology - Answer-Medications
/.Statins - Answer-lower cholesterol in the blood and reduce its production in the liver by
blocking the enzyme that produces it; has adverse effects that can occur more
frequently at higher doses.
/.LDL cholesterol - Answer-goal of < 70 in high risk patients
goal of < 100 in mod high-risk patients
/.DM pts w/ acute coronary artery syndrome & multiple or uncontrolled risk factors; Tx =
- Answer-TLC, changes in diet restrict refined carbs (sugar & liquid calories), wgt loss
(pt will not be able to participate in aerobic activity if had previous MI), decreased insulin
resistance, decreased BP, improved cardiovascular conditioning, limit/ restrict ETOH
consumption.
/.Which patients are easier to manage? - Answer-Patients at low risk for developing
heart dz.
/.What med is recommended if the LDL cannot be decreased by a high dose of potent
statin? - Answer-Nicotinic acid
/.Med combination to lower triglycerides and increase the HDL - Answer-a
fibrate/nicotinic acid with statin
, /.Patient Education for Statin - Answer-Pt to report report extreme fatigue, darked-color
urine, ck elevated, rhabdomylitis (muscle aches); if reported stop immediately and
check LFT(Liver Fxn Test)
/.lescol (Statin) - Answer-This med can affect liver function and increase liver enzymes
as well cause the pt to feel weak, fatigue and have muscle aches checking the LFT is
recommended
/.Acute drug induced hepatitis - Answer-the Liver enzymes are elevated w/ the use of
statin
/.If pt has acute and chronic hepatitis, liver disease cirrhosis and alcoholism; or
pregnant/breastfeeding mothers - Answer-DO NOT PRESCRIBE STATINS
/.First-line therapy for hyperlipidemia - Answer-Therapeutic Life Changes (TLC) Such
as: balanced diet, weight loss, minimize risk factors before medications
/.Which drug class is most effective for the management of hyperlipidemia with
concurrent elevated triglycerides (TGs)? - Answer-Fibrates
/.How do you identify the potential serious adverse drug reactions with hyperlipidemia
agents? - Answer-Monitor BP within 1 to 3 hours of administration to check for
hypotensive affect
/.What type of counseling would you give to a pt who just started on hyperlipidemia
agents, such as an HMG Co-A reductase inhibitor (statin), etc? - Answer-myopathy and
hepatatoxicity
/.What is the second line treatment options if a patient fails a statin? - Answer-Bile acid-
binding resins
/.Patient factors which preclude use of an HMG Co-A reductase inhibitor - Answer-
*patients with active hepatic disease or unexplained persistent elevations in
aminotransferase levels
* in pregnancy and during breastfeeding as cholesterol is an essential component for
fetal and infant synthesis of steroids and cell membrane development
*caution is necessary for patients with already increased blood glucose *levels or
increased Hba1c levels.
can increase the risk of statin-induced myopathy
/.Which hyperlipidemia agents are appropriate for use in pregnancy with respect to risk
to fetus as well as mother? - Answer-Fibrates
/.Which drug (statin) decrease LDL at a greatest percentage? - Answer-Rosuvastatin
/.Post MI dose of ASA - Answer-BMI > 29 = 325mg ASA
